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Gamma genesis in the basolateral amygdala (Feng et al 2019)
Feng Feng
FengEtAl2019_r1 [7039452]
Using in vitro and in vivo data we develop the first large-scale biophysically and anatomically realistic model of the basolateral amygdala nucleus (BL), which reproduces the dynamics of the in vivo local field potential (LFP). Significantly, it predicts that BL intrinsically generates the transient gamma oscillations observed in vivo. The model permitted exploration of the poorly understood synaptic mechanisms underlying gamma genesis in BL, and the model's ability to compute LFPs at arbitrary numbers of recording sites provided insights into the characteristics of the spatial properties of gamma bursts. Furthermore, we show how gamma synchronizes principal cells to overcome their low firing rates while simultaneously promoting competition, potentially impacting their afferent selectivity and efferent drive, and thus emotional behavior.
  • Feng F, Headley DB , Amir A, Kanta V, Chen Z, Pare D, Nair S (2019) Show Other
FengEtAl2019
  • Feng, Feng [ffvxb at mail.missouri.edu] Show Other
ffvxb@mail.missouri.edu
basolateral amygdala neurons
I K-DR
LFP
ffvxb@mail.missouri.edu
False
False
Other categories referring to Gamma genesis in the basolateral amygdala (Feng et al 2019)
Revisions: 10
Last Time: 2/7/2019 6:02:04 PM
Reviewer: Tom Morse - MoldelDB admin
Owner: Tom Morse - MoldelDB admin