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A computational model of action selection in the basal ganglia (Suryanarayana et al 2019)
Shreyas Suryanarayana
" ... Here, we incorporate newly revealed subgroups of neurons within the GPe into an existing computational model of the basal ganglia, and investigate their role in action selection. Three main results ensued. First, using previously used metrics for selection, the new extended connectivity improved the action selection performance of the model. Second, low frequency theta oscillations were observed in the subpopulation of the GPe (the TA or ‘arkypallidal’ neurons) which project exclusively to the striatum. These oscillations were suppressed by increased dopamine activity — revealing a possible link with symptoms of Parkinson’s disease. Third, a new phenomenon was observed in which the usual monotonic relationship between input to the basal ganglia and its output within an action ‘channel’ was, under some circumstances, reversed. ..."
  • Suryanarayana SM, Hellgren Kotaleski J, Grillner S, Gurney KN (2019) Show Other
  • Suryanarayana, Shreyas [shreyas.suryanarayana at ki.se] Show Other
  • Gurney, Kevin [K.Gurney at shef.ac.uk] Show Other
shreyas.suryanarayana@ki.se
PMID: 30414556
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Revisions: 9
Last Time: 1/12/2019 10:30:38 AM
Reviewer: Tom Morse - MoldelDB admin
Owner: Tom Morse - MoldelDB admin