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Respiratory central pattern generator including Kolliker-Fuse nucleus (Wittman et al 2019)
Jonathan Rubin
We present three highly reduced conductance-based models for the core of the respiratory CPG. All successfully simulate respiratory outputs across eupnoeic and vagotomized conditions and show that loss of inhibition to the pontine Kolliker-Fuse nucleus reproduces the key respiratory alterations associated with Rett syndrome.
  • Wittman S, Abdala AP, Rubin JE (2019) Show Other
WittmanEtAl2019
  • Wittman, Samuel [swittman52 at gmail.com] Show Other
jonrubin@pitt.edu
Respiratory CPG
Rhythmic network
Rhythm generation
Wittman, Samuel
Wittman, S., Abdala, A. P., & Rubin, J. E. (2019). Reduced computational modelling of Kölliker-Fuse contributions to breathing patterns in Rett syndrome. The Journal of Physiology, 597(10), 2651-2672.
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Revisions: 7
Last Time: 10/15/2019 3:19:52 PM
Reviewer: Tom Morse - MoldelDB admin
Owner: Tom Morse - MoldelDB admin