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Electrodecrements in in vitro model of infantile spasms (Traub et al 2020)
Roger Traub
plateauVFO11 [7152432]
The code is an extension of the thalamocortical model of Traub et al. (2005) J Neurophysiol. It is here applied to an in vitro model of the electrodecremental response seen in the EEG of children with infantile spasms (West syndrome)
  • Thalamus geniculate nucleus/lateral principal GLU cell Show Other
  • Thalamus reticular nucleus GABA cell Show Other
  • Neocortex U1 L6 pyramidal corticalthalamic GLU cell Show Other
  • Neocortex U1 L2/6 pyramidal intratelencephalic GLU cell Show Other
  • Neocortex layer 4 pyramidal cell Show Other
  • Neocortex fast spiking (FS) interneuron Show Other
  • Neocortex spiking regular (RS) neuron Show Other
  • Neocortex spiking low threshold (LTS) neuron Show Other
  • Neocortex spiny stellate cell Show Other
  • Traub RD, Moeller F, Rosch R, Baldeweg T, Whittington MA, Hall SP (2020) Show Other
  • Hall S, Hunt M, Simon A, Cunnington LG, Carracedo LM, Schofield IS, Forsyth R, Traub RD, Whittington MA (2015) Show Other
  • Carracedo LM, Kjeldsen H, Cunnington L, Jenkins A, Schofield I, Cunningham MO, Davies CH, Traub RD, Whittington MA (2013) Show Other
  • Traub, Roger D [rtraub at us.ibm.com] Show Other
rtraub@us.ibm.com
Code written by RD Traub, rtraub@us.ibm.com
Seizure initiation in infantile spasms vs. focal seizures: proposed common cellular mechanisms. Traub RD, Moeller F, Rosch R, Baldeweg T, Whittington MA, Hall SP. Rev Neurosci. 2020 Jan 28;31(2):181-200. doi: 10.1515/revneuro-2019-0030. Unbalanced Peptidergic Inhibition in Superficial Neocortex Underlies Spike and Wave Seizure Activity. Hall S, Hunt M, Simon A, Cunnington LG, Carracedo LM, Schofield IS, Forsyth R, Traub RD, Whittington MA. A neocortical delta rhythm facilitates reciprocal interlaminar interactions via nested theta rhythms. Carracedo LM, Kjeldsen H, Cunnington L, Jenkins A, Schofield I, Cunningham MO, Davies CH, Traub RD, Whittington MA. J Neurosci. 2013 Jun 26;33(26):10750-61. doi: 10.1523/JNEUROSCI.0735-13.2013. J Neurosci. 2015 Jun 24;35(25):9302-14. doi: 10.1523/JNEUROSCI.4245-14.2015.
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Revisions: 5
Last Time: 4/15/2020 1:48:03 PM
Reviewer: Tom Morse - MoldelDB admin
Owner: Tom Morse - MoldelDB admin