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Data
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Hyperpolarization-activated inward current and dynamic range of electrical synapse (Stein et al '22)
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Wolfgang Stein
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Electrical synaptic transmission and voltage-gated ionic currents are often studied independently from one another. This model allows to study the interactions between the hyperpolarization-activated inward ionic current and a rectifying electrical synapse. Two single compartment nonspiking neurons are coupled through a rectifying electrical synapse. Current pulses are applied into the presynaptic neuron. The amplitude of the electrical postsynaptic potentials is measured. Ih can be added to either the pre- or postsynaptic neuron, or both. The cells represent the the MCN1 and LG neurons in the crab stomatogastric ganglion.
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Stomatogastric Ganglion (STG) Modulatory commissural neuron 1 (MCN1) Show
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Stomatogastric Ganglion (STG) Lateral Gastric (LG) cell Show
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Hodgkin-Huxley neuron Show
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Stein W, DeMaegd ML, Braun LY, Vidal-Gadea A, Harris AL, Städele C (2022) Show
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wstein@ilstu.edu
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The hyperpolarization-activated current shifts the dynamic range of a voltage-dependent electrical synapse
Wolfgang Stein, Margaret L. DeMaegd, Lena Yolanda Braun, Andrés Vidal-Gadea, Allison L. Harris, Carola Städele
bioRxiv 2021.12.16.472972; doi: https://doi.org/10.1101/2021.12.16.472972
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