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Data
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Axonal subthreshold voltage signaling along hippocampal mossy fiber (Kamiya 2022)
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Haruyuki Kamiya
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Subthreshold depolarization of soma passively propagates into the axons for a substantial distance and thereby caused enhancement of the transmitter release from the axon terminals of hippocampal mossy fibers. Here we developed the granule cell-mossy fiber model implemented with axonal sodium potassium and calcium channels and explored the mechanisms underlying analog modulation of the action potential-evoked transmitter release by subthreshold voltage signaling along the axons. Action potential-induced calcium entry to the terminals was reduced, while subthreshold depolarization itself caused small calcium entry.
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Kamiya, Haruyuki [kamiya at med.hokudai.ac.j] Show
Other
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kamiya@med.hokudai.ac.jp
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Subthreshold signaling
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Front. Cell. Neurosci., 2022
https://doi.org/10.3389/fncel.2022.966636
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