|
|
|
Data
|
CA1 pyr cell: phenomenological NMDAR-based model of synaptic plasticity (Dainauskas et al 2023)
|
Ausra Saudargiene
|
|
|
|
|
This Python code implements a phenomenological NMDA receptor-based voltage-dependent model of synaptic plasticity for CA3-CA1 synapse and shows weight changes of a synapse placed on a two-compartmental model of a hippocampal CA1 pyramidal neuron for spike-timing-dependent synaptic plasticity (STDP) and frequency-dependent synaptic plasticity stimulation protocols. The developed model predicts altered learning rules in synapses formed on the apical dendrites of the detailed compartmental model of CA1 pyramidal neuron in the presence of the GluN2B-NMDA receptor hypofunction.
|
-
Hippocampus CA1 pyramidal GLU cell Show
Other
|
|
|
|
|
|
|
|
|
|
|
|
|
-
Dainauskas JJ, Marie H, Migliore M, Saudargiene A Show
Other
|
|
|
|
|
|
|
|
|
|
|
|
ausra.saudargiene@lsmu.lt
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Dainauskas, Justinas [justinas.dainauskas at gmail.com]
Saudargiene, Ausra [ausra.saudargiene at lsmu.lt]
|
|
|
Dainauskas JJ, Marie H, Migliore M and Saudargiene A. GluN2B-NMDAR subunit contribution on synaptic plasticity: a phenomenological model for CA3-CA1 synapses. Frontiers in Synaptic Neuroscience 2023. DOI: 10.3389/fnsyn.2023.1113957
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
