BrainPharm: Computational model - Theta-gamma phase amplitude coupling in a hippocampal CA1 microcircuit (Ponzi et al. 2023)

Computational model

Data

Name

Theta-gamma phase amplitude coupling in a hippocampal CA1 microcircuit (Ponzi et al. 2023)

Submitter name

Michele Migliore

Pipeline ID

Model File

scanzres [1937346]

Notes

Using a data-driven model of a hippocampal microcircuit, we demonstrate that theta-gamma phase amplitude coupling (PAC) can naturally emerge from a single feedback mechanism involving an inhibitory and excitatory neuron population, which interplay to generate theta frequency periodic bursts of higher frequency gamma..

Model Neurons

Hippocampus CA1 pyramidal GLU cell Show Other

More Cells

Hippocampus CA1 stratum oriens lacunosum-moleculare interneuron Show Other
Hippocampus CA1 basket cell Show Other

Model Currents

I h Show Other
I K,Ca Show Other
I K Show Other
I Calcium Show Other
I CAN Show Other
I M Show Other
I Na,t Show Other
Ca pump Show Other
I A Show Other
I T low threshold Show Other
I L high threshold Show Other
I_KD Show Other

Model Receptors

Gaba Show Other
Glutamate Show Other

Model Type

Realistic Network Show Other

Model Concept

Oscillations Show Other
Gamma oscillations Show Other
Theta oscillations Show Other

Simulator software

NetPyNE Show Other

Model papers

Ponzi A, Dura-Bernal S, Migliore M (accepted) Show Other

Gene

hg folder name (applicable when in ModelDB hg)

Region Organism

Hippocampus Show Other

Model ID Number

Gap Junctions

Implemented by

Public Submitter Email Address

michele.migliore@pa.ibf.cnr.it

Other Neuron

Model Neurotransmitters

Glutamate Show Other
Gaba Show Other

Other Receptor

Other Current

Other Neurotransmitter

Other Model Type

Other Concept

Other Simulator

Other Implementer

Alternative Version

Citation

Theta-gamma phase amplitude coupling in a hippocampal CA1 microcircuit, Adam Ponzi, Salvador Dura-Bernal, Michele Migliore. PLoS CB 2023

Default File Notes

Other Gene

Simulation Platform ID

Has Model View

False

Component

RAM

Hide Auto-launch button

False

Run Protocols

ICG Channel Details

Species

Other categories referring to Theta-gamma phase amplitude coupling in a hippocampal CA1 microcircuit (Ponzi et al. 2023)

Revisions:	7
Last Time:	3/6/2023 5:00:59 PM
Reviewer:	System Administrator
Owner:	Michele Migliore