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Relating anatomical and biophysical properties to motoneuron excitabilty (Moustafa et al. 2023)
Ted Carnevale
Nonlinear dynamical analysis of spinal motoneuron reveals effects of SK, CaL channels, and cell morphology on excitability, with implications for pathophysiology of ALS.
  • Moustafa M, Mousa MH, Saad MS, Basha T, Elbasiouny SM Show Other
https://github.com/fnsneuralsimulator
ted.carnevale@yale.edu
Spinal motor neuron, not otherwise specified
Reduced model
CaL warmup & stochast gat
Stuff that didn't fit the above fields: Concepts should include F-I curve hysteresis, co-localization of CaL and SK channels, CaL warm-up and stochastic gating (phenomena displayed by L channels, important to motoneuron function).
Moustafa, Muhammad and Mousa, Mohamed H and Saad, Mohamed S and Basha, Tamer and Elbasiouny, Sherif M Front Cell Neurosci. 2023 Feb 16;17:1093199. doi: 10.3389/fncel.2023.1093199. eCollection 2023.
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Other categories referring to Relating anatomical and biophysical properties to motoneuron excitabilty (Moustafa et al. 2023)
Revisions: 27
Last Time: 4/5/2023 11:04:59 AM
Reviewer: Rhea Rajvansh
Owner: Tom Morse - MoldelDB admin