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Data
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Active dendrites and spike propagation in a hippocampal interneuron (Saraga et al 2003)
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We create multi-compartment models of an Oriens-Lacunosum/Moleculare (O-LM) hippocampal interneuron using passive properties, channel kinetics, densities and distributions specific to this cell type, and explore its signaling characteristics. We find that spike initiation depends on both location and amount of input, as well as the intrinsic properties of the interneuron. Distal synaptic input always produces strong back-propagating spikes whereas proximal input could produce both forward and back-propagating spikes depending on the input strength. Please see paper for more details.
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Hippocampus CA1 interneuron oriens alveus GABA cell Show
Other
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Neuron or other electrically excitable cell Show
Other
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Saraga F, Wu CP, Zhang L, Skinner FK (2003) Show
Other
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OLMmodel
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Saraga, Fernanda [Fernanda.Saraga at utoronto.ca] Show
Other
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148
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