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Data
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Kenyon cells in the honeybee (Wustenberg et al 2004)
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The mushroom body of the insect brain is an important locus for olfactory information
processing and associative learning. ... Current- and voltage-clamp analyses were
performed on cultured Kenyon cells from honeybees. ... Voltage-clamp analyses characterized a
fast transient Na+ current (INa), a delayed rectifier K+ current (IK,V) and a fast transient K+ current
(IK,A). Using the neurosimulator SNNAP, a Hodgkin-Huxley type model was developed and
used to investigate the roles of the different currents during spiking. The model led to the
prediction of a slow transient outward current (IK,ST) that was subsequently identified by reevaluating
the voltage-clamp data. Simulations indicated that the primary currents that underlie
spiking are INa and IK,V, whereas IK,A and IK,ST primarily determined the responsiveness of the
model to stimuli such constant or oscillatory injections of current. See paper for more details.
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Neuron or other electrically excitable cell Show
Other
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Wüstenberg DG, Boytcheva M, Grünewald B, Byrne JH, Menzel R, Baxter DA (2004) Show
Other
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Baxter, Douglas Show
Other
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Boytcheva, Milena [milena at cs.tu-berlin.de] Show
Other
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Wustenberg, Daniel [Daniel.Wustenberg at uth.tmc.edu] Show
Other
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