Computational model
Kenyon cells in the honeybee (Wustenberg et al 2004)
kenyon [?]
The mushroom body of the insect brain is an important locus for olfactory information processing and associative learning. ... Current- and voltage-clamp analyses were performed on cultured Kenyon cells from honeybees. ... Voltage-clamp analyses characterized a fast transient Na+ current (INa), a delayed rectifier K+ current (IK,V) and a fast transient K+ current (IK,A). Using the neurosimulator SNNAP, a Hodgkin-Huxley type model was developed and used to investigate the roles of the different currents during spiking. The model led to the prediction of a slow transient outward current (IK,ST) that was subsequently identified by reevaluating the voltage-clamp data. Simulations indicated that the primary currents that underlie spiking are INa and IK,V, whereas IK,A and IK,ST primarily determined the responsiveness of the model to stimuli such constant or oscillatory injections of current. See paper for more details.
  • Neuron or other electrically excitable cell Show Other
  • Wüstenberg DG, Boytcheva M, Grünewald B, Byrne JH, Menzel R, Baxter DA (2004) Show Other
  • Baxter, Douglas Show Other
  • Boytcheva, Milena [milena at] Show Other
  • Wustenberg, Daniel [Daniel.Wustenberg at] Show Other
Kenyon cell
Other categories referring to Kenyon cells in the honeybee (Wustenberg et al 2004)
Revisions: 10
Last Time: 10/17/2018 3:40:57 PM
Reviewer: Tom Morse - MoldelDB admin
Owner: Tom Morse - MoldelDB admin