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Data
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Bursting activity of neuron R15 in Aplysia (Canavier et al 1991, Butera et al 1995)
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An equivalent circuit model of the R15 bursting neuron in Aplysia has been combined with a fluid compartment model, resulting in a model that incorporates descriptions of most of the membrane ion channels that are known to exist in the somata of R15, as well as providing a Ca2+ balance on the cell. ... (from the second paper) we have implemented proposed mechanisms for the modulation of two ionic currents (IR and ISI) that play key roles in regulating its spontaneous electrical activity. The model was sufficient to simulate a wide range of endogenous activity in the presence of various concentrations of 5-HT or DA. See papers for more and details.
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Neuron or other electrically excitable cell Show
Other
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Butera RJ, Clark JW, Canavier CC, Baxter DA, Byrne JH (1995) Show
Other
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Canavier CC, Clark JW, Byrne JH (1991) Show
Other
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