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T channel currents (Vitko et al 2005)
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Computer simulations predict that seven of the SNPs would increase firing of neurons, with three of them inducing oscillations at similar frequencises. 3 representative models from the paper have been submited: a wild-type (WT) recombinant Cav3.2 T-channel, and two of the
mutants described in the Vitko et al., 2005 paper (C456S and R788C). See the paper for more and details.
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Vitko I, Chen Y, Arias JM, Shen Y, Wu XR, Perez-Reyes E (2005) Show
Other
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