Pathological mechanism
beta-Amyloid activates I_L by MAP Kinase
  • Dendritic Hypothesis - Ca++ currents Show Other
  • Activation of the L voltage-sensitive calcium channel by mitogen-activated protein (MAP) kinase following exposure of neuronal cells to beta-amyloid. MAP kinase mediates beta-amyloid-induced neurodegeneration. Show Other
"(Our experimental) findings indicate that redirection rather than increased activation of MAP-Kinase activity mediates beta_Amyloid-induced neurotoxicity." (Ekinci FJ et al. 1999).
Exclude - Neurotoxicity
Other categories referring to beta-Amyloid activates I_L by MAP Kinase
Revisions: 11
Last Time: 10/27/2017 9:47:56 PM
Reviewer: System Administrator
Owner: System Administrator