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Data
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Fluctuating synaptic conductances recreate in-vivo-like activity (Destexhe et al 2001)
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This model (and experiments) reported in Destexhe, Rudolh, Fellous, and Sejnowski (2001) support the hypothesis that many of the
characteristics of cortical neurons in vivo can be explained by fast glutamatergic and GABAergic conductances varying stochastically.
Some of these cortical neuron characteristics of fluctuating synaptic origin are a depolarized membrane potential, the
presence of high-amplitude membrane potential fluctuations, a low input resistance and irregular spontaneous firing activity. In addition, the
point-conductance model could simulate the enhancement of responsiveness due to background activity.
For more information please contact Alain Destexhe. email: Destexhe@iaf.cnrs-gif.fr
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Destexhe A, Rudolph M, Fellous JM, Sejnowski TJ (2001) Show
Other
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fluct
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Destexhe, Alain [Destexhe at iaf.cnrs-gif.fr] Show
Other
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