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Recording from rod bipolar axon terminals in situ (Oltedal et al 2007)
oltedal [?]
"... Whole cell recordings from axon terminals and cell bodies were used to investigate the passive membrane properties of rod bipolar cells and analyzed with a two-compartment equivalent electrical circuit model developed by Mennerick et al. For both terminal- and soma-end recordings, capacitive current decays were well fitted by biexponential functions. Computer simulations of simplified models of rod bipolar cells demonstrated that estimates of the capacitance of the axon terminal compartment can depend critically on the recording location, with terminal-end recordings giving the best estimates. Computer simulations and whole cell recordings demonstrated that terminal-end recordings can yield more accurate estimates of the peak amplitude and kinetic properties of postsynaptic currents generated at the axon terminals due to increased electrotonic filtering of these currents when recorded at the soma. ..." See paper for more and details.
  • Neuron or other electrically excitable cell Show Other
  • Oltedal L, Mørkve SH, Veruki ML, Hartveit E (2007) Show Other
  • Mennerick S, Zenisek D, Matthews G (1997) Show Other
  • Oltedal, Leif [Leif.Oltedal at biomed.uib.no] Show Other
tom.morse@yale.edu
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Last Time: 7/26/2015 1:29:57 PM
Reviewer: Tom Morse - MoldelDB admin
Owner: Tom Morse - MoldelDB admin