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Endothelin action on pituitary latotrophs (Bertram et al. 2006)
Endothelin (ET-1, -2, and -3 designate three genes which produce different endothelin isopeptides) is a prolactin inhibiting substance of hypothalmic origin. ET-1 binding is part of at least four G protein signaling pathways in lactotrophs. The sequence of events in these pathways following the presentation of nano- and pico-molar concentrations of ET-1 is modeled in the paper.
  • Neuron or other electrically excitable cell Show Other
  • Bertram R, Tabak J, Toporikova N, Freeman ME (2006) Show Other
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Revisions: 7
Last Time: 5/9/2007 10:06:03 AM
Reviewer: Tom Morse - MoldelDB admin
Owner: Tom Morse - MoldelDB admin