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Data
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Activity dependent conductances in a neuron model (Liu et al. 1998)
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"... We present a model of a
stomatogastric ganglion (STG) neuron in which several Ca2+-dependent
pathways are used to regulate the maximal conductances of membrane
currents in an activity-dependent manner. Unlike previous models of
this type, the regulation and modification of maximal conductances by
electrical activity is unconstrained. The model has seven
voltage-dependent membrane currents and uses three Ca2+ sensors acting
on different time scales. ... The model suggests that neurons may regulate their
conductances to maintain fixed patterns of electrical activity, rather
than fixed maximal conductances, and that the regulation process
requires feedback systems capable of reacting to changes of electrical
activity on a number of different time scales."
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Neuron or other electrically excitable cell Show
Other
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Liu Z, Golowasch J, Marder E, Abbott LF (1998) Show
Other
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93321
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Morse, Tom [Tom.Morse at Yale.edu] Show
Other
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tom.morse@yale.edu
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149
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