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Activity dependent conductances in a neuron model (Liu et al. 1998)
"... We present a model of a stomatogastric ganglion (STG) neuron in which several Ca2+-dependent pathways are used to regulate the maximal conductances of membrane currents in an activity-dependent manner. Unlike previous models of this type, the regulation and modification of maximal conductances by electrical activity is unconstrained. The model has seven voltage-dependent membrane currents and uses three Ca2+ sensors acting on different time scales. ... The model suggests that neurons may regulate their conductances to maintain fixed patterns of electrical activity, rather than fixed maximal conductances, and that the regulation process requires feedback systems capable of reacting to changes of electrical activity on a number of different time scales."
  • Neuron or other electrically excitable cell Show Other
  • Liu Z, Golowasch J, Marder E, Abbott LF (1998) Show Other
  • Morse, Tom [Tom.Morse at Yale.edu] Show Other
tom.morse@yale.edu
STG neuron
149
True
False
Other categories referring to Activity dependent conductances in a neuron model (Liu et al. 1998)
Revisions: 19
Last Time: 1/2/2015 9:54:56 PM
Reviewer: Robert A McDougal
Owner: Tom Morse - MoldelDB admin