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Data
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Kinetics of the P2X7 receptor as expressed in Xenopus oocytes (Riedel et al. 2007a,b)
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"Human P2X7 receptors were expressed in Xenopus laevis oocytes and
single channels were recorded using the patch-clamp technique in the
outside-out configuration. ATP4- evoked two types of P2X7
receptor-mediated single channel currents characterized by short-lived
and long-lived openings. ... The kinetics of the short channel
openings at negative membrane potentials fitted well to a linear
C-C-C-O model with two ATP4- binding steps at equal binding sites
...." and "Using the patch-clamp method, we studied the influence of
external alkali and organic monovalent cations on the single-channel
properties of the adenosine triphosphate (ATP)-activated recombinant
human P2X(7) receptor." See the references for more.
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Riedel T, Schmalzing G, Markwardt F (2007) Show
Other
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Riedel T, Lozinsky I, Schmalzing G, Markwardt F (2007) Show
Other
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fritz.markwardt@medizin.uni-halle.de
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microglia, macrophage, B lymphocyte
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ATP
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PMID: 17483156, PMID: 17189308
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