|
|
|
Data
|
Model of DARPP-32 phosphorylation in striatal medium spiny neurons (Lindskog et al. 2006)
|
|
|
|
|
|
|
The work describes a model of how transient calcium and dopamine inputs might affect phosphorylation of DARPP-32 in the medium spiny neurons in the striatum. The model is relevant for understanding both the "three-factor rule" for synaptic plasticity in corticostriatal synapses, and also for relating reinforcement learning theories to biology.
|
-
Neostriatum medium spiny direct pathway GABA cell Show
Other
|
|
|
|
|
|
|
|
|
|
|
|
|
-
Lindskog M, Kim M, Wikström MA, Blackwell KT, Kotaleski JH (2006) Show
Other
|
|
|
|
|
|
|
|
|
|
|
|
jeanette@csc.kth.se
|
medium spiny neuron
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Lindskog M, Kim M, Wikstrom M, Blackwell KT, Hellgren Kotaleski J (2006), PLoS Comput Biol 2(9):e119
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
