BrainPharm: Computational model - Theta phase precession in a model CA3 place cell (Baker and Olds 2007)

Computational model

Data

Name

Theta phase precession in a model CA3 place cell (Baker and Olds 2007)

Submitter name

Pipeline ID

Model File

bakerolds2007 [?]

Notes

"... The present study concerns a neurobiologically based computational model of the emergence of theta phase precession in which the responses of a single model CA3 pyramidal cell are examined in the context of stimulation by realistic afferent spike trains including those of place cells in entorhinal cortex, dentate gyrus, and other CA3 pyramidal cells. Spike-timing dependent plasticity in the model CA3 pyramidal cell leads to a spatially correlated associational synaptic drive that subsequently creates a spatially asymmetric expansion of the model cell’s place field. ... Through selective manipulations of the model it is possible to decompose theta phase precession in CA3 into the separate contributing factors of inheritance from upstream afferents in the dentate gyrus and entorhinal cortex, the interaction of synaptically controlled increasing afferent drive with phasic inhibition, and the theta phase difference between dentate gyrus granule cell and CA3 pyramidal cell activity."

Model Neurons

Hippocampus CA3 pyramidal GLU cell Show Other

More Cells

Model Currents

I Na,p Show Other
I Na,t Show Other
I L high threshold Show Other
I N Show Other
I T low threshold Show Other
I A Show Other
I K,leak Show Other
I M Show Other
I h Show Other
I K,Ca Show Other
I Sodium Show Other
I Calcium Show Other
I Mixed Show Other
I Potassium Show Other

Model Receptors

GabaA Show Other
GabaB Show Other
AMPA Show Other
NMDA Show Other

Model Type

Neuron or other electrically excitable cell Show Other

Model Concept

Oscillations Show Other
Simplified Models Show Other
Active Dendrites Show Other
Detailed Neuronal Models Show Other
Synaptic Plasticity Show Other
Short-term Synaptic Plasticity Show Other
Long-term Synaptic Plasticity Show Other
Methods Show Other
Learning Show Other
Reinforcement Learning Show Other
STDP Show Other
Place cell/field Show Other
Calcium dynamics Show Other

Simulator software

C or C++ program Show Other
MATLAB Show Other

Model papers

Baker JL, Olds JL (2007) Show Other

Gene

NR2A GRIN2A Show Other

hg folder name (applicable when in ModelDB hg)

Region Organism

Model ID Number

Gap Junctions

Implemented by

Baker, John L [jbakerb at gmu.edu] Show Other

Public Submitter Email Address

Other Neuron

Model Neurotransmitters

Acetylcholine Show Other
Gaba Show Other
Glutamate Show Other

Other Receptor

Other Current

Other Neurotransmitter

Other Model Type

Other Concept

Place Cell

Other Simulator

Other Implementer

Baker, John L

Alternative Version

Citation

Default File Notes

Other Gene

Simulation Platform ID

Has Model View

False

Component

RAM

Hide Auto-launch button

False

Run Protocols

ICG Channel Details

Species

Other categories referring to Theta phase precession in a model CA3 place cell (Baker and Olds 2007)

Revisions:	11
Last Time:	7/14/2009 1:58:15 PM
Reviewer:	Tom Morse - MoldelDB admin
Owner:	Tom Morse - MoldelDB admin