Computational model
Theta phase precession in a model CA3 place cell (Baker and Olds 2007)
"... The present study concerns a neurobiologically based computational model of the emergence of theta phase precession in which the responses of a single model CA3 pyramidal cell are examined in the context of stimulation by realistic afferent spike trains including those of place cells in entorhinal cortex, dentate gyrus, and other CA3 pyramidal cells. Spike-timing dependent plasticity in the model CA3 pyramidal cell leads to a spatially correlated associational synaptic drive that subsequently creates a spatially asymmetric expansion of the model cell’s place field. ... Through selective manipulations of the model it is possible to decompose theta phase precession in CA3 into the separate contributing factors of inheritance from upstream afferents in the dentate gyrus and entorhinal cortex, the interaction of synaptically controlled increasing afferent drive with phasic inhibition, and the theta phase difference between dentate gyrus granule cell and CA3 pyramidal cell activity."
  • Hippocampus CA3 pyramidal GLU cell Show Other
  • Neuron or other electrically excitable cell Show Other
  • Baker, John L [jbakerb at] Show Other
Place Cell
Baker, John L
Other categories referring to Theta phase precession in a model CA3 place cell (Baker and Olds 2007)
Revisions: 11
Last Time: 7/14/2009 1:58:15 PM
Reviewer: Tom Morse - MoldelDB admin
Owner: Tom Morse - MoldelDB admin