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"Cerebellar Purkinje cells mediate accurate eye movement
coordination. However, it remains unclear how oculomotor
adaptation depends on the interplay between the characteristic
Purkinje cell response patterns, namely tonic, bursting, and
spike pauses. Here, a spiking cerebellar model assesses the role
of Purkinje cell firing patterns in vestibular ocular
reflex (VOR) adaptation. The model captures the cerebellar
microcircuit properties and it incorporates spike-based synaptic
plasticity at multiple cerebellar sites. ..." |
