Circuits that contain the Receptor : NO
| Models | Description | |
| 1. | Diffusive homeostasis in a spiking network model (Sweeney et al. 2015) | |
| In this paper we propose a new mechanism, diffusive homeostasis, in which neural excitability is modulated by nitric oxide, a gas which can flow freely across cell membranes. Our model simulates the activity-dependent synthesis and diffusion of nitric oxide in a recurrent network model of integrate-and-fire neurons. The concentration of nitric oxide is then used as homeostatic readout which modulates the firing threshold of each neuron. | ||