"Intracellular recordings of neuronal membrane potential are a central tool in neurophysiology.
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We introduce a computer-aided technique, Active Electrode Compensation (AEC), based on a digital model of the electrode interfaced in real time with the electrophysiological setup.
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AEC should be particularly useful to characterize fast neuronal phenomena intracellularly in vivo."
Reference:
1 .
Brette R, Piwkowska Z, Monier C, Rudolph-Lilith M, Fournier J, Levy M, Frégnac Y, Bal T, Destexhe A (2008) High-resolution intracellular recordings using a real-time computational model of the electrode. Neuron 59:379-91 [PubMed]
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