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Spike Response Model simulator (Jolivet et al. 2004, 2006, 2008)
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The Spike Response Model (SRM) optimized on the experimental data in the Single-Neuron modelling Competition ( www.incf.org/community/competitions ) for edition 2007 and edition 2008. The Spike Response Model is a simplified model of neuronal excitability where current linearly integrates to an artificial threshold. After the spike, the threshold is augmented and the voltage follows a voltage kernel that is the average voltage trace during and after a spike. The parameters were chosen to best fit the observed spike times with a method outlined in Jolivet et al. (2006).
Jolivet R, Rauch A, Lüscher HR, Gerstner W (2006) Predicting spike timing of neocortical pyramidal neurons by simple threshold models.
J Comput Neurosci
Jolivet R, Lewis TJ, Gerstner W (2004) Generalized integrate-and-fire models of neuronal activity approximate spike trains of a detailed model to a high degree of accuracy.
Jolivet R, Kobayashi R, Rauch A, Naud R, Shinomoto S, Gerstner W (2008) A benchmark test for a quantitative assessment of simple neuron models.
J Neurosci Methods
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Neuron or other electrically excitable cell;
Action Potential Initiation;
Mensi, Skander [skander.mensi at epfl.ch];
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