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Short term plasticity at the cerebellar granule cell (Nieus et al. 2006)
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The model reproduces short term plasticity of the mossy fibre to granule cell synapse. To reproduce synaptic currents recorded in experiments, a model of presynaptic release was used to determine the concentration of glutamate in the synaptic cleft that ultimately determined a synaptic response. The parameters of facilitation and depression were determined deconvolving AMPA EPSCs.
Nieus T, Sola E, Mapelli J, Saftenku E, Rossi P, D'Angelo E (2006) LTP regulates burst initiation and frequency at mossy fiber-granule cell synapses of rat cerebellum: experimental observations and theoretical predictions.
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Cerebellum interneuron granule GLU cell;
Short-term Synaptic Plasticity;
Nieus, Thierry [thierry.nieus at iit.it];
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Cerebellum interneuron granule GLU cell
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