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Extraction and classification of three cortical neuron types (Mensi et al. 2012)
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This script proposes a new convex fitting procedure that allows the parameters estimation of a large class of stochastic Integrate-and-Fire model upgraded with spike-triggered current and moving threshold from patch-clamp experiments (i.e. given the injected current and the recorded membrane potential). This script applies the method described in the paper to estimate the parameters of a reference model from a single voltage trace and the corresponding input current and evaluate the performance of the fitted model on a separated test set.
Mensi S, Naud R, Pozzorini C, Avermann M, Petersen CC, Gerstner W (2012) Parameter extraction and classification of three cortical neuron types reveals two distinct adaptation mechanisms.
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Neuron or other electrically excitable cell;
Hippocampus CA1 pyramidal GLU cell;
Hippocampus CA3 pyramidal GLU cell;
Neocortex fast spiking (FS) interneuron;
Neocortex spiking regular (RS) neuron;
Mensi, Skander [skander.mensi at epfl.ch];
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Hippocampus CA1 pyramidal GLU cell
Hippocampus CA3 pyramidal GLU cell
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