Dendro-dendritic synaptic circuit (Shepherd Brayton 1979)

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Accession:144385
A NEURON simulation has been created to model the passive spread of an EPSP from a mitral cell synapse on a granule cell spine. The EPSP was shown to propagate subthreshold through the dendritic shaft into an adjacent spine with significant amplitude (figure 2B).
Reference:
1 . Shepherd GM, Brayton RK (1979) Computer simulation of a dendrodendritic synaptic circuit for self- and lateral-inhibition in the olfactory bulb. Brain Res 175:377-82 [PubMed]
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Model Information (Click on a link to find other models with that property)
Model Type: Dendrite;
Brain Region(s)/Organism:
Cell Type(s):
Channel(s):
Gap Junctions:
Receptor(s):
Gene(s):
Transmitter(s):
Simulation Environment: NEURON;
Model Concept(s): Influence of Dendritic Geometry; Olfaction;
Implementer(s): Morse, Tom [Tom.Morse at Yale.edu];
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ShepherdBrayton1979
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ParmFitness: Fig 2B Shepherd Brayton 1979
	FitnessGenerator: GR_1
		RegionFitness:	Spine[0].head.v(0.5)

	FitnessGenerator: GR_8
		RegionFitness:	GR_8.v(0.5)

	FitnessGenerator: GR_3
		RegionFitness:	Spine[1].head.v(0.5)

	FitnessGenerator: GR_10
		RegionFitness:	GR_10.v(0.5)

	Parameters:
		"Ri", 80, 8, 800, 1, 1
		"Cm", 1, 0.5, 2, 1, 1
		"Rm", 4000, 400, 40000, 1, 1
		"start_of_ramp", 0.525, 0.5, 1.5, 1, 1
		"delta_of_ramp", 0.2, 0.02, 1, 1, 1
		"delta_of_plateau", 0.8, 0.02, 1, 1, 1
		"g_max_param", 0.008, 0.0008, 0.08, 1, 1
End ParmFitness