Cardiac action potentials and pacemaker activity of sinoatrial node (DiFrancesco & Noble 1985)

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Accession:144520
"Equations have been developed to describe cardiac action potentials and pacemaker activity. The model takes account of extensive developments in experimental work ..."
Reference:
1 . DiFrancesco D, Noble D (1985) A model of cardiac electrical activity incorporating ionic pumps and concentration changes. Philos Trans R Soc Lond B Biol Sci 307:353-98 [PubMed]
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Model Information (Click on a link to find other models with that property)
Model Type: Neuron or other electrically excitable cell;
Brain Region(s)/Organism:
Cell Type(s): Cardiac atrial cell; Cardiac ventricular cell;
Channel(s): I Na,t; I K; I h; I Calcium; I Potassium; Na/Ca exchanger; Na/K pump;
Gap Junctions:
Receptor(s):
Gene(s): HCN4;
Transmitter(s):
Simulation Environment: NEURON;
Model Concept(s): Action Potentials;
Implementer(s): Gannier, Francois [francois.gannier at univ-tours.fr];
Search NeuronDB for information about:  I Na,t; I K; I h; I Calcium; I Potassium; Na/Ca exchanger; Na/K pump;
TITLE sodium Background Current
COMMENT
	modified From DiFrancesco & Noble 1985 Phil Trans R Soc Lond 307:353-398 
    modified for Neuron by FE GANNIER
	francois.gannier@univ-tours.fr (University of TOURS)
ENDCOMMENT
INCLUDE "Unit.inc"
INCLUDE "Volume.inc"
NEURON { SUFFIX ibg 
	USEION na READ ena WRITE ina
	USEION ca READ eca WRITE ica
	RANGE gCa, gNa, ina, ica
}
PARAMETER {
	gNa = 0.18	(uS)		<0,1e9>
	gCa = 0.02	(uS)		<0,1e9>
}

ASSIGNED {
	celsius (degC)
	v (mV) 
	ina (mA/cm2)  
	ica (mA/cm2)  
	ena (mV)
	eca (mV)
	dummy
}

BREAKPOINT {
	ina =  (1e-06)*gNa/S*(v - ena)
	ica =  (1e-06)*gCa/S*(v - eca)
}