A set of reduced models of layer 5 pyramidal neurons (Bahl et al. 2012)

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These are the NEURON files for 10 different models of a reduced L5 pyramidal neuron. The parameters were obtained by automatically fitting the models to experimental data using a multi objective evolutionary search strategy. Details on the algorithm can be found at http://www.g-node.org/emoo and in Bahl et al. (2012).
1 . Bahl A, Stemmler MB, Herz AV, Roth A (2012) Automated optimization of a reduced layer 5 pyramidal cell model based on experimental data. J Neurosci Methods 210:22-34 [PubMed]
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Model Information (Click on a link to find other models with that property)
Model Type: Neuron or other electrically excitable cell; Dendrite;
Brain Region(s)/Organism:
Cell Type(s): Neocortex U1 L5B pyramidal pyramidal tract GLU cell;
Channel(s): I Na,p; I Na,t; I K; I M; I h; I K,Ca; I Calcium; I A, slow;
Gap Junctions:
Simulation Environment: NEURON;
Model Concept(s): Action Potential Initiation; Parameter Fitting; Simplified Models; Active Dendrites; Detailed Neuronal Models; Action Potentials; Methods; Calcium dynamics;
Implementer(s): Bahl, Armin [bahl at neuro.mpg.de];
Search NeuronDB for information about:  Neocortex U1 L5B pyramidal pyramidal tract GLU cell; I Na,p; I Na,t; I K; I M; I h; I K,Ca; I Calcium; I A, slow;

forall e_pas = -80.398657
Rm_axosomatic = 20587.734598
forsec axosomatic_list cm = 2.230408
spinefactor = 0.784797
soma gbar_nat = 236.616175
soma gbar_kfast = 67.197508
soma gbar_kslow = 475.820646
soma gbar_nap = 1.443953
soma gbar_km = 10.459916
basal gbar_ih = 11.039583
tuft gbar_ih = 16.194815
tuft gbar_nat = 47.817841
decay_kfast = 20.075497
decay_kslow = 37.711817
hillock gbar_nat = 9512.289205
iseg gbar_nat = 13326.766938
iseg vshift2_nat = -10.612583

Ra_apical = 382.22414867
apical Ra = Ra_apical
tuft gbar_sca = 0.45423528
tuft vshift_sca = 7.19485311
tuft gbar_kca = 6.15058501