A set of reduced models of layer 5 pyramidal neurons (Bahl et al. 2012)

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These are the NEURON files for 10 different models of a reduced L5 pyramidal neuron. The parameters were obtained by automatically fitting the models to experimental data using a multi objective evolutionary search strategy. Details on the algorithm can be found at http://www.g-node.org/emoo and in Bahl et al. (2012).
1 . Bahl A, Stemmler MB, Herz AV, Roth A (2012) Automated optimization of a reduced layer 5 pyramidal cell model based on experimental data. J Neurosci Methods 210:22-34 [PubMed]
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Model Information (Click on a link to find other models with that property)
Model Type: Neuron or other electrically excitable cell; Dendrite;
Brain Region(s)/Organism:
Cell Type(s): Neocortex U1 L5B pyramidal pyramidal tract GLU cell;
Channel(s): I Na,p; I Na,t; I K; I M; I h; I K,Ca; I Calcium; I A, slow;
Gap Junctions:
Simulation Environment: NEURON;
Model Concept(s): Action Potential Initiation; Parameter Fitting; Simplified Models; Active Dendrites; Detailed Neuronal Models; Action Potentials; Methods; Calcium dynamics;
Implementer(s): Bahl, Armin [bahl at neuro.mpg.de];
Search NeuronDB for information about:  Neocortex U1 L5B pyramidal pyramidal tract GLU cell; I Na,p; I Na,t; I K; I M; I h; I K,Ca; I Calcium; I A, slow;

forall e_pas = -80.735127
Rm_axosomatic = 11594.384797
forsec axosomatic_list cm = 2.336857
spinefactor = 0.500000
soma gbar_nat = 402.172079
soma gbar_kfast = 41.351830
soma gbar_kslow = 264.787820
soma gbar_nap = 4.179878
soma gbar_km = 14.917361
basal gbar_ih = 11.921506
tuft gbar_ih = 15.266638
tuft gbar_nat = 11.555568
decay_kfast = 91.798929
decay_kslow = 75.607992
hillock gbar_nat = 8030.326751
iseg gbar_nat = 17591.201145
iseg vshift2_nat = -5.982169

Ra_apical = 358.47
apical Ra = Ra_apical
tuft gbar_sca = 3.86
tuft vshift_sca = 3.79
tuft gbar_kca = 9.60