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Dendritic signals command firing dynamics in a Cerebellar Purkinje Cell model (Genet et al. 2010)
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This model endows the dendrites of a reconstructed Purkinje cells (PC) with the mechanism of Ca-dependent plateau potentials and spikes described in Genet, S., and B. Delord. 2002. A biophysical model of nonlinear dynamics underlying plateau potentials and calcium spikes in Purkinje cell dendrites. J. Neurophysiol. 88:2430–2444). It is a part of a comprehensive mathematical study suggesting that active electric signals in the dendrites of PC command epochs of firing and silencing of the PC soma.
Genet S, Sabarly L, Guigon E, Berry H, Delord B (2010) Dendritic signals command firing dynamics in a mathematical model of cerebellar Purkinje cells.
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Neuron or other electrically excitable cell;
Cerebellum Purkinje GABA cell;
Dendritic Action Potentials;
Detailed Neuronal Models;
Genet, Stéphane [email@example.com];
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Cerebellum Purkinje GABA cell
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