Impact of dendritic atrophy on intrinsic and synaptic excitability (Narayanan & Chattarji, 2010)

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Accession:147867
These simulations examined the atrophy induced changes in electrophysiological properties of CA3 pyramidal neurons. We found these neurons change from bursting to regular spiking as atrophy increases. Region-specific atrophy induced region-specific increases in synaptic excitability in a passive dendritic tree. All dendritic compartments of an atrophied neuron had greater synaptic excitability and a larger voltage transfer to the soma than the control neuron.
Reference:
1 . Narayanan R, Chattarji S (2010) Computational analysis of the impact of chronic stress on intrinsic and synaptic excitability in the hippocampus. J Neurophysiol 103:3070-83 [PubMed]
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Model Information (Click on a link to find other models with that property)
Model Type: Neuron or other electrically excitable cell; Synapse; Dendrite;
Brain Region(s)/Organism: Hippocampus;
Cell Type(s): Hippocampus CA3 pyramidal GLU cell;
Channel(s): I Na,t; I L high threshold; I N; I T low threshold; I A; I K; I M; I h; I K,Ca; I Calcium; I_AHP;
Gap Junctions:
Receptor(s): AMPA;
Gene(s):
Transmitter(s): Glutamate;
Simulation Environment: NEURON;
Model Concept(s): Active Dendrites; Influence of Dendritic Geometry; Detailed Neuronal Models; Action Potentials; Conductance distributions;
Implementer(s): Narayanan, Rishikesh [rishi at iisc.ac.in];
Search NeuronDB for information about:  Hippocampus CA3 pyramidal GLU cell; AMPA; I Na,t; I L high threshold; I N; I T low threshold; I A; I K; I M; I h; I K,Ca; I Calcium; I_AHP; Glutamate;
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{pt3dadd(62.71,-62.204,-4.5,1.12)}
{pt3dadd(65.436,-61.818,-26.75,1.12)}
{pt3dadd(65.489,-62.031,-19.5,1.12)}
{pt3dadd(69.399,-67.843,-30.5,1.12)}
{pt3dadd(78.098,-69.918,-30,1.12)}
{pt3dadd(78.35,-70.078,-29.25,1.12)}
{pt3dadd(78.35,-70.078,-29.225,0.8)}
{pt3dadd(79.839,-74.212,-21.370,0.8)}

{soma[3] connect soma[4](0), 1}
{access soma[4]}
{pt3dclear()}
{pt3dadd(-1.476,-7.621,1,11.3)}
{pt3dadd(-1.476,-10.002,1,10.02)}
{pt3dadd(-1.689,-11.744,1,9.38)}
{pt3dadd(-1.064,-13.712,1,7.16)}
{pt3dadd(-1.064,-14.79,1,5.26)}
{pt3dadd(-0.638,-15.88,1,3.66)}
{pt3dadd(-0.638,-16.532,1,3.66)}

{soma[0] connect apical[0](0), 1}
{access apical[0]}
{pt3dclear()}
{pt3dadd(-11.438,43.504,2.25,4.3)}
{pt3dadd(-12.914,46.776,14.75,4.3)}

{apical[0] connect apical[1](0), 1}
{access apical[1]}
{pt3dclear()}
{pt3dadd(-12.914,46.776,14.75,4.3)}
{pt3dadd(-14.404,50.686,9,5.88)}
{pt3dadd(-17.157,52.868,9.25,3.02)}
{pt3dadd(-18.846,56.352,9,3.02)}
{pt3dadd(-19.059,57.217,9.25,3.02)}

{apical[1] connect apical[2](0), 1}
{access apical[2]}
{pt3dclear()}
{pt3dadd(-19.059,57.217,9.25,3.02)}
{pt3dadd(-22.025,60.05,9.5,2.08)}
{pt3dadd(-23.927,63.095,9.5,2.08)}
{pt3dadd(-23.927,65.915,9.75,1.76)}
{pt3dadd(-23.714,68.535,9.75,1.76)}
{pt3dadd(-24.991,70.264,9.75,1.76)}
{pt3dadd(-31.122,71.793,9.75,1.76)}
{pt3dadd(-37.054,74.187,9.75,1.76)}
{pt3dadd(-45.739,82.021,27,1.76)}
{pt3dadd(-50.181,86.144,27,1.76)}
{pt3dadd(-50.181,86.37,27,1.76)}
{pt3dadd(-51.032,99.205,27,1.76)}
{pt3dadd(-50.607,99.644,27.5,1.76)}
{pt3dadd(-50.607,99.644,27.525,1.12)}
{pt3dadd(-46.164,102.25,36.5,1.12)}
{pt3dadd(-46.164,102.038,35.75,1.12)}
{pt3dadd(-44.129,103.634,32.25,1.44)}
{pt3dadd(-43.012,106.427,41.75,1.44)}
{pt3dadd(-43.345,106.334,38.75,0.8)}
{pt3dadd(-45.632,109.339,41,1.12)}
{pt3dadd(-46.63,112.279,41,1.12)}
{pt3dadd(-50.061,117.559,47.5,1.12)}
{pt3dadd(-50.354,118.184,44.25,1.12)}
{pt3dadd(-51.045,122.041,45.5,1.12)}
{pt3dadd(-52.602,124.262,46.25,1.12)}
{pt3dadd(-52.841,124.448,46.25,1.12)}
{pt3dadd(-57.124,138.387,42,1.12)}
{pt3dadd(-59.052,141.871,42.5,1.12)}
{pt3dadd(-58.972,141.233,43,1.12)}
{pt3dadd(-59.172,141.206,43,1.12)}
{pt3dadd(-60.635,149.572,41.5,1.12)}
{pt3dadd(-63.986,157.698,41.75,1.12)}
{pt3dadd(-66.686,162.194,48.5,1.12)}
{pt3dadd(-66.5,162.433,48.75,1.12)}
{pt3dadd(-69.931,169.469,32.75,1.12)}
{pt3dadd(-72.751,176.784,32.75,1.12)}
{pt3dadd(-78.537,189.006,30.75,1.12)}
{pt3dadd(-84.921,202.679,31,1.12)}
{pt3dadd(-86.171,207.573,31,1.12)}
{pt3dadd(-87.142,206.788,32,1.12)}
{pt3dadd(-87.487,219.902,32,1.12)}
{pt3dadd(-87.514,220.115,32,1.12)}
{pt3dadd(-87.381,220.793,32,1.12)}

{apical[2] connect apical[3](0), 1}
{access apical[3]}
{pt3dclear()}
{pt3dadd(-87.381,220.793,32,1.12)}
{pt3dadd(-87.381,220.793,32.025,0.48)}
{pt3dadd(-91.092,224.571,29,0.48)}
{pt3dadd(-91.331,224.757,29,0.48)}
{pt3dadd(-97.183,234.12,29,0.48)}
{pt3dadd(-105.349,241.435,29,0.48)}
{pt3dadd(-114.22,251.077,48.75,0.48)}
{pt3dadd(-117.12,257.302,48.75,0.48)}
{pt3dadd(-121.748,260.241,48.75,0.48)}
{pt3dadd(-123.517,265.934,42.25,0.48)}
{pt3dadd(-126.443,268.86,36.75,0.48)}
{pt3dadd(-126.47,269.072,36.75,0.48)}
{pt3dadd(-127.614,274.858,34.75,0.48)}
{pt3dadd(-132.694,277.957,40.25,0.48)}
{pt3dadd(-132.721,278.17,40.25,0.48)}
{pt3dadd(-134.569,284.514,26.5,0.48)}
{pt3dadd(-134.596,284.726,26.25,0.48)}
{pt3dadd(-134.896,284.967,29.225,0.48)}

{apical[2] connect apical[4](0), 1}
{access apical[4]}
{pt3dclear()}
{pt3dadd(-87.381,220.793,32,1.12)}
{pt3dadd(-87.567,220.554,32,1.12)}
{pt3dadd(-84.229,238.496,32,1.12)}
{pt3dadd(-84.256,238.708,32,1.12)}
{pt3dadd(-82.181,247.739,32,1.44)}
{pt3dadd(-81.755,258.1,32,1.44)}
{pt3dadd(-82.048,258.712,32,1.44)}

{apical[4] connect apical[5](0), 1}
{access apical[5]}
{pt3dclear()}
{pt3dadd(-82.048,258.712,32,1.44)}
{pt3dadd(-82.048,258.712,32.025,0.8)}
{pt3dadd(-87.78,261.877,47.5,0.8)}
{pt3dadd(-85.679,265.654,48.25,0.8)}
{pt3dadd(-85.705,265.867,48.25,0.8)}
{pt3dadd(-93.127,272.397,34,0.8)}
{pt3dadd(-93.153,272.61,34,0.8)}
{pt3dadd(-92.408,278.622,42.25,0.8)}
{pt3dadd(-92.435,278.848,41.5,0.8)}
{pt3dadd(-97.994,282.319,39,0.8)}
{pt3dadd(-98.979,288.557,39,0.8)}
{pt3dadd(-110.35,299.423,32,0.8)}
{pt3dadd(-111.441,304.77,32,0.8)}
{pt3dadd(-111.693,305.169,32,0.8)}
{pt3dadd(-114.566,307.669,25.75,0.8)}
{pt3dadd(-114.899,312.018,25.5,0.8)}
{pt3dadd(-117.439,313.667,25,0.8)}
{pt3dadd(-117.665,318.907,25,0.8)}
{pt3dadd(-117.692,319.12,25,0.8)}
{pt3dadd(-120.964,323.097,25,0.8)}
{pt3dadd(-124.408,325.079,47.75,0.8)}
{pt3dadd(-124.461,325.518,47.5,0.8)}
{pt3dadd(-124.692,332.085,41.350,0.8)}

{apical[4] connect apical[6](0), 1}
{access apical[6]}
{pt3dclear()}
{pt3dadd(-82.048,258.712,32,1.44)}
{pt3dadd(-82.261,258.685,32,1.44)}
{pt3dadd(-78.723,264.604,32,1.12)}
{pt3dadd(-78.709,269.658,32,1.12)}
{pt3dadd(-78.736,269.87,32,1.12)}
{pt3dadd(-75.956,275.031,32,1.12)}
{pt3dadd(-73.243,282.386,32,1.12)}
{pt3dadd(-69.586,295.992,32.25,1.12)}
{pt3dadd(-73.044,301.484,32.25,1.12)}
{pt3dadd(-73.283,301.671,32.25,1.12)}
{pt3dadd(-68.974,313.388,32.25,1.12)}
{pt3dadd(-69,313.601,32.25,1.12)}
{pt3dadd(-65.769,315.09,32.5,1.12)}
{pt3dadd(-65.981,316.819,32.75,1.12)}
{pt3dadd(-65.769,316.846,32.75,1.12)}
{pt3dadd(-59.877,324.374,32.75,1.12)}
{pt3dadd(-59.903,324.587,32.75,1.12)}
{pt3dadd(-62.217,329.561,32.75,1.12)}
{pt3dadd(-62.244,329.787,32.75,1.12)}
{pt3dadd(-58.706,340.746,32.75,1.12)}
{pt3dadd(-58.733,340.959,32.75,1.12)}
{pt3dadd(-56.339,342.355,32.75,1.12)}
{pt3dadd(-56.365,342.568,32.75,1.12)}
{pt3dadd(-57.456,346.159,32.75,1.12)}
{pt3dadd(-54.942,353.487,32.75,1.12)}
{pt3dadd(-58.028,359.459,43.5,1.12)}
{pt3dadd(-58.241,359.433,43.5,1.12)}
{pt3dadd(-57.669,361.694,43.5,1.12)}
{pt3dadd(-57.163,362.851,39.25,1.12)}
{pt3dadd(-57.163,362.851,39.275,0.8)}
{pt3dadd(-55.94,369.221,38,0.8)}
{pt3dadd(-54.211,372.506,38,0.8)}
{pt3dadd(-53.36,377.654,38,0.8)}
{pt3dadd(-54.317,380.167,38,0.8)}
{pt3dadd(-51.883,388.134,42.75,0.8)}
{pt3dadd(-51.936,391.68,36.715,0.8)}

{apical[1] connect apical[7](0), 1}
{access apical[7]}
{pt3dclear()}
{pt3dadd(-19.059,57.217,9.25,3.02)}
{pt3dadd(-19.059,57.217,9.275,1.44)}
{pt3dadd(-17.157,63.747,14.25,1.44)}
{pt3dadd(-16.731,68.535,14.25,1.44)}
{pt3dadd(-18.421,72.658,9.75,1.44)}
{pt3dadd(-18.633,77.007,4.75,1.44)}
{pt3dadd(-18.846,77.233,7,1.44)}
{pt3dadd(-18.846,88.113,21.25,1.44)}
{pt3dadd(-18.846,88.325,21.25,1.44)}
{pt3dadd(-15.667,95.507,21,1.44)}
{pt3dadd(-18.633,103.993,14.5,1.44)}
{pt3dadd(-18.846,103.993,14.5,1.44)}
{pt3dadd(-19.485,107.903,14.25,1.44)}
{pt3dadd(-19.697,107.903,14.25,1.44)}
{pt3dadd(-20.961,113.343,21,1.44)}
{pt3dadd(-21.174,127.055,21.75,1.44)}
{pt3dadd(-20.322,130.313,22.25,1.12)}
{pt3dadd(-20.322,130.965,22.25,1.12)}

{apical[7] connect apical[8](0), 1}
{access apical[8]}
{pt3dclear()}
{pt3dadd(-20.322,130.965,22.25,1.12)}
{pt3dadd(-20.322,130.965,22.275,0.8)}
{pt3dadd(-18.208,135.101,14.5,0.8)}
{pt3dadd(-17.569,137.495,14.5,0.8)}
{pt3dadd(-17.569,137.708,14.5,0.8)}
{pt3dadd(-21.174,142.283,27.75,0.8)}
{pt3dadd(-19.272,149.678,27.75,0.8)}
{pt3dadd(-22.45,153.815,27.75,0.8)}
{pt3dadd(-22.863,160.119,27.75,0.8)}
{pt3dadd(-22.863,160.332,27.75,0.8)}
{pt3dadd(-20.535,161.422,33.25,0.8)}
{pt3dadd(-20.535,161.209,33.25,0.8)}
{pt3dadd(-21.386,168.378,33.25,0.8)}
{pt3dadd(-22.238,171.424,32.5,0.8)}
{pt3dadd(-16.944,175.134,21,0.8)}
{pt3dadd(-15.242,180.348,36.25,0.8)}
{pt3dadd(-15.455,180.348,36.25,0.8)}
{pt3dadd(-12.914,181,38,0.48)}
{pt3dadd(-12.276,184.923,38,0.48)}
{pt3dadd(-12.276,185.136,38,0.48)}
{pt3dadd(-9.111,185.349,38,0.48)}
{pt3dadd(-9.111,185.575,38,0.48)}
{pt3dadd(-6.145,190.576,26,0.48)}
{pt3dadd(-2.753,195.789,26.25,0.48)}
{pt3dadd(-2.966,195.789,26.25,0.48)}
{pt3dadd(-2.54,196.454,26,0.48)}

{apical[8] connect apical[9](0), 1}
{access apical[9]}
{pt3dclear()}
{pt3dadd(-2.54,196.454,26,0.48)}
{pt3dadd(-2.54,196.454,26.025,0.48)}
{pt3dadd(-1.064,199.713,11,0.48)}
{pt3dadd(-3.391,200.577,11,0.48)}
{pt3dadd(-3.604,200.803,11,0.48)}
{pt3dadd(-4.868,202.546,11,0.48)}
{pt3dadd(-5.081,202.546,11,0.48)}
{pt3dadd(-4.229,206.243,11,0.48)}
{pt3dadd(-4.229,206.456,11,0.48)}
{pt3dadd(-8.047,207.972,8,0.48)}
{pt3dadd(-7.195,210.592,21.25,0.48)}
{pt3dadd(-7.408,210.592,21.25,0.48)}
{pt3dadd(-9.111,214.29,30,0.48)}
{pt3dadd(-9.323,214.29,30,0.48)}
{pt3dadd(-12.276,216.684,26,0.48)}
{pt3dadd(-12.702,216.684,29.5,0.48)}
{pt3dadd(-14.617,221.897,18,0.48)}
{pt3dadd(-12.489,231.034,31,0.48)}
{pt3dadd(-10.8,239.094,16.75,0.48)}
{pt3dadd(-10.587,243.004,16.75,0.48)}
{pt3dadd(-10.587,243.217,16.75,0.48)}
{pt3dadd(-9.736,245.837,16.75,0.48)}
{pt3dadd(-9.736,246.05,16.75,0.48)}
{pt3dadd(-10.8,251.051,22,0.48)}
{pt3dadd(-10.8,251.277,22,0.48)}
{pt3dadd(-8.047,257.581,21.5,0.48)}
{pt3dadd(-8.047,257.794,21.5,0.48)}
{pt3dadd(-7.195,262.808,14,0.48)}
{pt3dadd(-4.868,267.157,28,0.48)}
{pt3dadd(-3.604,271.945,28,0.48)}
{pt3dadd(-1.902,273.022,28,0.48)}
{pt3dadd(-2.328,275.416,28,0.48)}
{pt3dadd(-2.328,275.643,28,0.48)}
{pt3dadd(-0.213,278.249,28,0.48)}
{pt3dadd(-0.426,283.463,28,0.48)}
{pt3dadd(-0.213,283.689,28,0.48)}
{pt3dadd(-0.213,287.599,29.25,0.48)}
{pt3dadd(-0.213,287.825,29.25,0.48)}
{pt3dadd(2.115,290.219,29.25,0.48)}
{pt3dadd(3.391,301.737,17.5,0.48)}
{pt3dadd(3.179,306.964,24.25,0.48)}
{pt3dadd(2.753,309.797,24.25,0.48)}
{pt3dadd(2.54,309.797,24.25,0.48)}
{pt3dadd(0.851,314.359,19.25,0.48)}
{pt3dadd(0.638,315.011,19,0.48)}
{pt3dadd(0.638,315.237,19,0.48)}
{pt3dadd(0,328.284,14.5,0.48)}
{pt3dadd(-0.925,336.23,14.5,0.48)}

{apical[8] connect apical[10](0), 1}
{access apical[10]}
{pt3dclear()}
{pt3dadd(-2.54,196.454,26,0.48)}
{pt3dadd(2.328,202.971,29,0.48)}
{pt3dadd(3.179,211.683,31.5,0.48)}
{pt3dadd(5.932,216.458,31.5,0.48)}
{pt3dadd(5.932,216.684,31.5,0.48)}
{pt3dadd(4.229,219.729,31.5,0.48)}
{pt3dadd(8.259,224.078,31.5,0.48)}
{pt3dadd(6.77,226.246,31.5,0.48)}
{pt3dadd(8.047,230.822,31.5,0.48)}
{pt3dadd(8.233,230.768,27.5,0.48)}
{pt3dadd(8.326,233.402,25,0.48)}
{pt3dadd(7.315,238.11,21,0.48)}
{pt3dadd(5.413,246.635,40,0.48)}
{pt3dadd(3.391,256.038,48.25,0.48)}
{pt3dadd(2.221,265.535,25.75,0.48)}
{pt3dadd(2.195,265.747,25.75,0.48)}
{pt3dadd(2.101,266.702,28.592,0.48)}

{apical[7] connect apical[11](0), 1}
{access apical[11]}
{pt3dclear()}
{pt3dadd(-20.322,130.965,22.25,1.12)}
{pt3dadd(-21.174,137.495,15.75,0.8)}
{pt3dadd(-20.11,144.451,15.5,0.8)}
{pt3dadd(-18.208,154.679,14.5,0.8)}
{pt3dadd(-17.569,161.635,14.75,0.8)}
{pt3dadd(-17.782,170.12,8.5,0.8)}
{pt3dadd(-17.782,170.346,8,0.8)}
{pt3dadd(-18.208,180.135,5.5,0.8)}
{pt3dadd(-18.208,180.348,5.5,0.8)}
{pt3dadd(-13.978,193.834,4.5,0.8)}
{pt3dadd(-11.012,199.5,13,0.8)}
{pt3dadd(-10.8,199.713,13.25,0.8)}

{apical[11] connect apical[12](0), 1}
{access apical[12]}
{pt3dclear()}
{pt3dadd(-10.8,199.713,13.25,0.8)}
{pt3dadd(-12.914,201.881,5.5,0.8)}
{pt3dadd(-12.914,202.107,6.25,0.8)}
{pt3dadd(-13.553,206.895,25.25,0.8)}
{pt3dadd(-11.438,210.153,25.25,0.8)}
{pt3dadd(-15.455,216.032,25.25,0.8)}
{pt3dadd(-15.667,216.032,25.25,0.8)}
{pt3dadd(-20.11,222.988,25.25,0.8)}
{pt3dadd(-20.11,223.201,25.25,0.8)}
{pt3dadd(-15.88,225.821,30,0.8)}
{pt3dadd(-21.812,233.654,30.25,0.8)}
{pt3dadd(-21.599,233.867,31.5,0.8)}
{pt3dadd(-16.332,234.519,31,1.12)}
{pt3dadd(-6.304,236.195,30.75,1.12)}
{pt3dadd(-6.331,236.408,30.75,1.12)}
{pt3dadd(-2.474,239.733,30.75,0.8)}
{pt3dadd(-2.687,243.217,30.75,1.12)}
{pt3dadd(-4.469,250.665,39.25,1.12)}
{pt3dadd(-5.48,258.871,34,1.12)}
{pt3dadd(-7.022,264.391,21.75,1.12)}
{pt3dadd(-7.155,267.224,29.5,1.12)}
{pt3dadd(-5.44,275.762,28.5,1.12)}
{pt3dadd(-5.466,275.975,28.5,1.12)}
{pt3dadd(-6.73,281.082,27,0.8)}
{pt3dadd(-6.943,281.056,27,0.8)}
{pt3dadd(-4.323,292.56,44,0.8)}
{pt3dadd(-4.522,292.534,44,0.8)}
{pt3dadd(-7.98,299.782,42,0.8)}
{pt3dadd(-7.874,307.469,40,0.8)}
{pt3dadd(-8.698,324.467,39.75,0.8)}
{pt3dadd(-8.778,325.105,39,0.8)}

{apical[12] connect apical[13](0), 1}
{access apical[13]}
{pt3dclear()}
{pt3dadd(-8.778,325.105,39,0.8)}
{pt3dadd(-8.778,325.105,39.025,0.8)}
{pt3dadd(-4.881,326.542,49.75,0.8)}
{pt3dadd(-4.908,326.768,49.75,0.8)}
{pt3dadd(-4.974,330.705,45,0.8)}
{pt3dadd(-3.192,335.306,45,0.8)}
{pt3dadd(-3.219,335.519,45,0.8)}
{pt3dadd(-0.878,333.843,42.75,0.8)}
{pt3dadd(-1.117,334.03,42.75,0.8)}
{pt3dadd(-2.128,338.724,52.75,0.8)}
{pt3dadd(-2.155,338.937,52.75,0.8)}
{pt3dadd(0.16,340.985,49,0.8)}
{pt3dadd(0.186,340.759,49,0.8)}
{pt3dadd(0.133,342.954,49,0.8)}
{pt3dadd(0.319,343.193,48.75,0.8)}
{pt3dadd(0.412,345.84,38.5,0.48)}
{pt3dadd(3.272,348.606,44,0.48)}
{pt3dadd(2.979,350.974,44,0.48)}
{pt3dadd(5.892,351.559,50.75,0.48)}
{pt3dadd(5.865,351.772,49,0.48)}
{pt3dadd(4.668,357.983,43.25,0.48)}
{pt3dadd(4.642,358.196,43.25,0.48)}
{pt3dadd(8.047,361.68,48,0.48)}
{pt3dadd(10.347,368.982,56,0.48)}
{pt3dadd(10.175,373.783,52.75,0.48)}
{pt3dadd(11.012,379.156,51,0.48)}
{pt3dadd(10.986,379.369,51,0.48)}
{pt3dadd(12.608,381.763,52,0.48)}
{pt3dadd(9.895,384.716,59.5,0.48)}
{pt3dadd(11.81,386.485,59.5,0.48)}
{pt3dadd(12.17,386.964,59.5,0.48)}
{pt3dadd(10.853,388.998,50.75,0.48)}
{pt3dadd(11.066,389.025,51.25,0.48)}
{pt3dadd(13.3,389.956,62,0.48)}
{pt3dadd(13.273,390.169,62,0.48)}
{pt3dadd(12.263,393.121,61.25,0.48)}
{pt3dadd(13.127,398.269,77.5,0.48)}
{pt3dadd(13.101,398.481,77.5,0.48)}
{pt3dadd(15.827,400.569,78,0.48)}
{pt3dadd(15.614,400.543,78,0.48)}
{pt3dadd(13.952,403.628,77.75,0.48)}
{pt3dadd(13.925,403.841,77.75,0.48)}
{pt3dadd(15.814,405.836,77.75,0.48)}
{pt3dadd(15.787,406.049,77.75,0.48)}
{pt3dadd(14.936,409.454,82.5,0.48)}
{pt3dadd(14.736,409.427,82.5,0.48)}
{pt3dadd(15.92,417.022,82.75,0.48)}
{pt3dadd(17.263,418.285,85.5,0.48)}
{pt3dadd(17.29,418.072,85.5,0.48)}
{pt3dadd(17.782,420.985,82.75,0.48)}
{pt3dadd(17.569,420.958,82.75,0.48)}
{pt3dadd(20.509,424.829,86.25,0.48)}
{pt3dadd(20.482,425.041,86.25,0.48)}
{pt3dadd(23.395,437.676,79.5,0.48)}
{pt3dadd(23.062,443.781,79.5,0.48)}
{pt3dadd(22.836,443.967,79.5,0.48)}
{pt3dadd(24.017,446.725,79.5,0.48)}

{apical[12] connect apical[14](0), 1}
{access apical[14]}
{pt3dclear()}
{pt3dadd(-8.778,325.105,39,0.8)}
{pt3dadd(-8.978,325.079,39,0.8)}
{pt3dadd(-10.946,332.287,52.25,0.8)}
{pt3dadd(-12.954,341.69,55.5,0.8)}
{pt3dadd(-17.436,350.335,55.25,0.8)}
{pt3dadd(-17.649,350.309,55.25,0.8)}
{pt3dadd(-14.564,352.889,55.25,0.8)}
{pt3dadd(-13.619,355.642,55.25,0.8)}
{pt3dadd(-11.651,356.972,55,0.8)}
{pt3dadd(-11.677,357.198,55,0.8)}
{pt3dadd(-12.867,361.84,56.427,0.8)}

{apical[11] connect apical[15](0), 1}
{access apical[15]}
{pt3dclear()}
{pt3dadd(-10.8,199.713,13.25,0.8)}
{pt3dadd(-10.8,199.713,13.275,0.48)}
{pt3dadd(-11.012,203.197,16,0.48)}
{pt3dadd(-10.8,207.759,7.75,0.48)}
{pt3dadd(-10.8,212.76,14.5,0.48)}
{pt3dadd(-10.161,216.032,14.5,0.48)}
{pt3dadd(-11.864,220.381,14.5,0.48)}
{pt3dadd(-12.063,220.594,14.5,0.48)}
{pt3dadd(-10.587,225.382,14.5,0.48)}
{pt3dadd(-11.438,228.64,14.5,0.48)}
{pt3dadd(-9.736,230.609,14.25,0.48)}
{pt3dadd(-12.276,240.171,14.25,0.48)}
{pt3dadd(-12.063,249.535,15.5,0.48)}
{pt3dadd(-12.276,249.535,15.25,0.48)}
{pt3dadd(-11.438,257.794,16.25,0.48)}
{pt3dadd(-9.523,261.93,3.5,0.48)}
{pt3dadd(-9.323,261.93,3.5,0.48)}
{pt3dadd(-9.523,263.673,3.5,0.48)}
{pt3dadd(-9.736,263.673,3.5,0.48)}
{pt3dadd(-6.77,267.809,3.5,0.48)}
{pt3dadd(-6.57,268.234,3.5,0.48)}
{pt3dadd(-7.408,273.022,3.5,0.48)}
{pt3dadd(-7.408,273.249,3.5,0.48)}
{pt3dadd(-3.604,281.082,3.5,0.48)}
{pt3dadd(-3.604,281.295,3.5,0.48)}
{pt3dadd(-5.293,284.341,3.25,0.48)}
{pt3dadd(-4.868,289.554,3.25,0.48)}
{pt3dadd(-6.77,293.691,0.5,0.48)}
{pt3dadd(-5.719,303.054,0.5,0.48)}
{pt3dadd(-5.932,303.479,0.5,0.48)}
{pt3dadd(-7.834,312.617,-1.5,0.48)}
{pt3dadd(-6.703,322.553,-1.5,0.48)}

{apical[0] connect apical[16](0), 1}
{access apical[16]}
{pt3dclear()}
{pt3dadd(-12.914,46.776,14.75,4.3)}
{pt3dadd(-12.914,46.776,14.775,3.34)}
{pt3dadd(-13.553,58.733,14.25,3.34)}
{pt3dadd(-13.34,61.566,18.75,3.02)}
{pt3dadd(-10.374,63.96,18.75,3.02)}
{pt3dadd(-11.651,68.748,18.5,2.4)}
{pt3dadd(-12.063,71.355,18.5,2.4)}
{pt3dadd(-8.047,78.975,18.5,2.4)}
{pt3dadd(-8.685,86.809,10.75,2.4)}
{pt3dadd(-8.898,96.372,5.5,2.4)}
{pt3dadd(-7.621,105.083,5.5,2.4)}
{pt3dadd(-7.621,105.296,5.5,2.4)}
{pt3dadd(-9.111,109.432,2.25,2.4)}
{pt3dadd(-8.898,114.22,-1.5,2.4)}
{pt3dadd(-6.357,118.995,0.75,2.08)}
{pt3dadd(-4.442,122.267,0.75,2.08)}
{pt3dadd(-4.229,122.267,0.75,2.08)}

{apical[16] connect apical[17](0), 1}
{access apical[17]}
{pt3dclear()}
{pt3dadd(-4.229,122.267,0.75,2.08)}
{pt3dadd(-4.229,122.267,0.775,0.8)}
{pt3dadd(1.064,126.616,6.7,0.8)}
{pt3dadd(3.179,125.964,7.45,0.8)}
{pt3dadd(3.179,125.964,7.475,0.8)}
{pt3dadd(3.491,125.586,6.603,0.8)}

{apical[16] connect apical[18](0), 1}
{access apical[18]}
{pt3dclear()}
{pt3dadd(-4.229,122.267,0.75,2.08)}
{pt3dadd(-3.817,125.313,0.75,1.76)}
{pt3dadd(-3.391,131.404,0.75,1.76)}
{pt3dadd(-3.817,132.92,0.75,1.76)}
{pt3dadd(-3.817,133.146,0.75,1.76)}
{pt3dadd(-0.426,137.495,0.75,1.76)}
{pt3dadd(-1.689,149.027,0.75,1.76)}
{pt3dadd(-0.638,149.678,0.7,1.76)}
{pt3dadd(-2.328,151.633,0.7,1.44)}
{pt3dadd(-1.476,156.634,0.7,1.44)}
{pt3dadd(1.689,162.513,0.7,1.44)}
{pt3dadd(1.689,162.726,0.7,1.44)}
{pt3dadd(2.115,166.862,0.7,1.44)}
{pt3dadd(1.277,177.741,0.7,1.44)}

{apical[18] connect apical[19](0), 1}
{access apical[19]}
{pt3dclear()}
{pt3dadd(1.277,177.741,0.7,1.44)}
{pt3dadd(1.277,177.741,0.725,1.44)}
{pt3dadd(1.277,178.606,0.7,1.44)}
{pt3dadd(3.179,182.529,1.45,1.44)}
{pt3dadd(3.391,185.575,1.45,1.44)}
{pt3dadd(3.604,186.227,1.45,1.44)}
{pt3dadd(7.408,192.744,-2.3,1.44)}
{pt3dadd(8.685,200.365,-4.05,1.44)}
{pt3dadd(8.685,200.577,-4.05,1.44)}
{pt3dadd(8.259,204.926,-1.8,1.44)}
{pt3dadd(8.259,205.591,-3.05,1.44)}

{apical[19] connect apical[20](0), 1}
{access apical[20]}
{pt3dclear()}
{pt3dadd(8.259,205.591,-3.05,1.44)}
{pt3dadd(8.259,205.591,-3.025,0.48)}
{pt3dadd(11.438,211.683,7.7,0.48)}
{pt3dadd(14.191,220.381,7.7,0.48)}
{pt3dadd(14.404,220.381,7.7,0.48)}
{pt3dadd(15.455,228.866,7.7,0.48)}
{pt3dadd(15.667,228.866,7.7,0.48)}
{pt3dadd(17.357,240.61,3.7,0.48)}
{pt3dadd(19.272,252.58,3.95,0.48)}
{pt3dadd(19.272,252.793,3.95,0.48)}
{pt3dadd(19.91,258.885,3.95,0.48)}
{pt3dadd(19.91,259.097,3.95,0.48)}
{pt3dadd(20.748,261.93,3.95,0.48)}
{pt3dadd(20.451,263.908,3.95,0.48)}

{apical[19] connect apical[21](0), 1}
{access apical[21]}
{pt3dclear()}
{pt3dadd(8.259,205.591,-3.05,1.44)}
{pt3dadd(9.111,207.108,-3.55,1.44)}
{pt3dadd(9.736,207.972,-6.3,1.44)}

{apical[21] connect apical[22](0), 1}
{access apical[22]}
{pt3dclear()}
{pt3dadd(9.736,207.972,-6.3,1.44)}
{pt3dadd(9.736,207.972,-6.275,0.48)}
{pt3dadd(7.834,208.637,12.2,0.48)}
{pt3dadd(7.121,211.551,12.2,0.48)}

{apical[21] connect apical[23](0), 1}
{access apical[23]}
{pt3dclear()}
{pt3dadd(9.736,207.972,-6.3,1.44)}
{pt3dadd(11.438,210.153,-2.8,1.12)}
{pt3dadd(12.489,212.108,-2.8,1.12)}
{pt3dadd(11.225,216.245,-2.8,1.12)}
{pt3dadd(12.702,217.987,-2.8,1.12)}
{pt3dadd(12.914,217.987,-2.8,1.12)}
{pt3dadd(15.455,221.033,-2.8,1.12)}
{pt3dadd(12.914,225.382,-3.05,1.12)}
{pt3dadd(12.914,225.595,-3.05,1.12)}
{pt3dadd(16.306,227.776,-3.05,1.12)}
{pt3dadd(16.306,227.989,-3.05,1.12)}
{pt3dadd(15.455,231.912,-4.8,1.12)}
{pt3dadd(16.731,237.126,-6.05,0.8)}
{pt3dadd(16.731,241.049,-9.8,0.8)}
{pt3dadd(18.208,248.444,-9.8,0.8)}
{pt3dadd(19.059,251.051,-9.8,0.8)}
{pt3dadd(20.961,251.929,-9.8,0.8)}
{pt3dadd(20.961,252.141,-9.8,0.8)}
{pt3dadd(23.714,259.762,-9.8,0.8)}
{pt3dadd(26.254,265.628,-9.8,0.8)}
{pt3dadd(26.041,268.899,-9.8,0.8)}
{pt3dadd(26.041,269.112,-9.8,0.8)}
{pt3dadd(31.973,274.326,-9.8,0.8)}
{pt3dadd(31.973,274.552,-9.8,0.8)}
{pt3dadd(32.186,280.856,-9.8,0.8)}
{pt3dadd(31.548,282.386,-17.3,0.8)}
{pt3dadd(36.203,286.296,-17.3,0.8)}
{pt3dadd(34.514,289.993,-17.3,0.8)}
{pt3dadd(34.301,289.993,-17.3,0.8)}
{pt3dadd(35.365,299.13,-17.3,0.8)}
{pt3dadd(35.152,299.13,-17.3,0.8)}
{pt3dadd(35.365,299.782,-17.3,0.8)}

{apical[23] connect apical[24](0), 1}
{access apical[24]}
{pt3dclear()}
{pt3dadd(35.365,299.782,-17.3,0.8)}
{pt3dadd(35.365,299.782,-17.275,0.8)}
{pt3dadd(38.956,301.524,-21.8,0.8)}
{pt3dadd(40.658,303.479,-21.8,0.8)}
{pt3dadd(40.658,305.222,-21.8,0.8)}
{pt3dadd(44.05,306.751,-27.55,0.8)}
{pt3dadd(45.739,311.1,-27.55,0.8)}
{pt3dadd(45.739,311.313,-27.55,0.8)}
{pt3dadd(49.343,310.661,-27.3,0.8)}
{pt3dadd(50.181,313.494,-26.8,0.48)}
{pt3dadd(53.36,315.011,-26.8,0.48)}
{pt3dadd(56.326,319.147,-18.3,0.48)}
{pt3dadd(61.619,319.147,-17.8,0.48)}
{pt3dadd(61.832,322.193,-17.8,0.48)}
{pt3dadd(61.832,322.405,-17.8,0.48)}
{pt3dadd(66.274,322.844,-17.55,0.48)}
{pt3dadd(66.487,322.844,-17.55,0.48)}
{pt3dadd(69.027,327.845,-17.55,0.48)}
{pt3dadd(69.027,328.071,-17.55,0.48)}
{pt3dadd(69.24,332.194,-17.55,0.48)}
{pt3dadd(71.993,332.194,-17.55,0.48)}
{pt3dadd(71.78,332.194,-17.55,0.48)}
{pt3dadd(73.27,338.286,-17.55,0.48)}
{pt3dadd(73.27,338.512,-17.55,0.48)}
{pt3dadd(76.648,339.376,-17.3,0.48)}
{pt3dadd(78.776,345.042,-17.3,0.48)}
{pt3dadd(78.563,345.042,-17.3,0.48)}
{pt3dadd(77.074,350.043,-17.3,0.48)}
{pt3dadd(84.907,356.56,-17.3,0.48)}
{pt3dadd(85.546,359.393,-5.8,0.48)}
{pt3dadd(85.333,359.393,-5.8,0.48)}
{pt3dadd(87.448,359.832,-5.8,0.48)}
{pt3dadd(89.562,362.226,-5.8,0.48)}
{pt3dadd(92.954,362.651,-5.8,0.48)}
{pt3dadd(96.132,368.53,-5.8,0.48)}
{pt3dadd(94.856,371.137,0.45,0.48)}
{pt3dadd(94.656,371.137,0.45,0.48)}
{pt3dadd(96.132,374.408,0.45,0.48)}
{pt3dadd(96.132,374.621,0.45,0.48)}
{pt3dadd(94.23,379.409,2.7,0.48)}
{pt3dadd(96.558,383.758,-14.55,0.48)}
{pt3dadd(96.558,383.971,-14.55,0.48)}
{pt3dadd(94.856,390.727,-14.3,0.48)}
{pt3dadd(94.656,390.727,-14.3,0.48)}
{pt3dadd(95.92,393.334,-14.05,0.48)}
{pt3dadd(95.707,393.108,-14.05,0.48)}
{pt3dadd(95.494,393.547,-14.05,0.48)}
{pt3dadd(94.018,398.987,-14.3,0.48)}
{pt3dadd(91.69,405.078,-14.3,0.48)}
{pt3dadd(89.15,407.033,-12.05,0.48)}
{pt3dadd(90.295,416.703,-3.438,0.48)}

{apical[23] connect apical[25](0), 1}
{access apical[25]}
{pt3dclear()}
{pt3dadd(35.365,299.782,-17.3,0.8)}
{pt3dadd(35.365,300.008,-17.3,0.8)}
{pt3dadd(33.662,303.479,-26.8,0.8)}
{pt3dadd(33.662,303.706,-26.8,0.8)}
{pt3dadd(35.152,308.919,-26.8,0.8)}
{pt3dadd(35.152,309.358,-26.8,0.8)}
{pt3dadd(33.875,315.888,-26.8,0.8)}
{pt3dadd(33.25,322.631,-36.55,0.8)}
{pt3dadd(33.25,322.844,-36.55,0.8)}
{pt3dadd(35.365,325.238,-36.55,0.8)}
{pt3dadd(31.122,342.209,-36.55,0.8)}
{pt3dadd(31.973,349.165,-36.55,0.8)}
{pt3dadd(27.318,362.226,-37.55,0.8)}
{pt3dadd(26.467,364.832,-37.55,0.8)}
{pt3dadd(25.829,365.697,-37.8,0.8)}

{apical[25] connect apical[26](0), 1}
{access apical[26]}
{pt3dclear()}
{pt3dadd(25.829,365.697,-37.8,0.8)}
{pt3dadd(25.204,371.137,-37.8,0.48)}
{pt3dadd(24.991,376.151,-38.05,0.48)}
{pt3dadd(24.778,376.363,-38.05,0.48)}
{pt3dadd(22.663,381.803,-38.05,0.48)}
{pt3dadd(20.961,385.288,-38.3,0.48)}
{pt3dadd(20.961,385.501,-38.3,0.48)}
{pt3dadd(22.025,392.031,-38.3,0.48)}
{pt3dadd(20.748,393.773,-41.05,0.48)}
{pt3dadd(20.322,398.774,-43.05,0.48)}
{pt3dadd(20.322,398.987,-43.05,0.48)}
{pt3dadd(20.535,407.259,-46.55,0.48)}
{pt3dadd(20.535,407.472,-46.55,0.48)}
{pt3dadd(19.272,409.866,-47.3,0.48)}
{pt3dadd(19.91,412.699,-47.3,0.48)}
{pt3dadd(19.91,412.912,-47.3,0.48)}
{pt3dadd(18.421,415.958,-47.3,0.48)}
{pt3dadd(19.697,419.216,-50.3,0.48)}
{pt3dadd(15.88,422.488,-50.3,0.48)}
{pt3dadd(15.029,434.232,-54.55,0.48)}
{pt3dadd(12.489,442.93,-40.55,0.48)}
{pt3dadd(10.161,446.415,-40.55,0.48)}
{pt3dadd(9.948,446.627,-40.55,0.48)}
{pt3dadd(9.523,448.809,-40.55,0.48)}
{pt3dadd(7.621,453.37,-38.55,0.48)}
{pt3dadd(7.834,455.113,-38.8,0.48)}
{pt3dadd(7.834,455.339,-38.8,0.48)}
{pt3dadd(6.57,457.507,-38.8,0.48)}
{pt3dadd(6.357,457.733,-38.8,0.48)}
{pt3dadd(7.195,459.462,-39.55,0.48)}
{pt3dadd(5.932,462.082,-31.05,0.48)}
{pt3dadd(5.506,463.598,-30.05,0.48)}
{pt3dadd(6.983,465.128,-43.55,0.48)}
{pt3dadd(5.719,469.038,-44.05,0.48)}
{pt3dadd(5.506,469.477,-44.05,0.48)}
{pt3dadd(6.589,475.378,-44.05,0.48)}

{apical[25] connect apical[27](0), 1}
{access apical[27]}
{pt3dclear()}
{pt3dadd(25.829,365.697,-37.8,0.8)}
{pt3dadd(25.829,365.697,-37.775,0.48)}
{pt3dadd(22.863,370.059,-23.55,0.48)}
{pt3dadd(17.569,376.802,-24.55,0.48)}
{pt3dadd(17.357,376.802,-24.55,0.48)}
{pt3dadd(17.569,378.97,-24.55,0.48)}
{pt3dadd(15.455,379.622,-24.55,0.48)}
{pt3dadd(15.242,379.622,-24.55,0.48)}
{pt3dadd(14.191,381.803,-24.55,0.48)}
{pt3dadd(12.914,382.668,-24.8,0.48)}
{pt3dadd(12.914,382.894,-24.8,0.48)}
{pt3dadd(13.127,387.243,-24.8,0.48)}
{pt3dadd(12.914,387.456,-24.8,0.48)}
{pt3dadd(12.914,387.682,-25.8,0.48)}
{pt3dadd(10.587,388.759,-11.05,0.48)}
{pt3dadd(10.374,388.759,-11.05,0.48)}
{pt3dadd(10.161,391.153,-11.05,0.48)}
{pt3dadd(9.736,391.592,-11.05,0.48)}
{pt3dadd(7.621,394.425,-11.05,0.48)}
{pt3dadd(7.621,394.638,-11.05,0.48)}
{pt3dadd(8.685,395.941,-11.05,0.48)}
{pt3dadd(8.259,397.471,-11.05,0.48)}
{pt3dadd(5.719,401.82,-6.3,0.48)}
{pt3dadd(5.293,405.517,-6.3,0.48)}
{pt3dadd(3.391,405.517,-6.3,0.48)}
{pt3dadd(3.179,405.517,-6.3,0.48)}
{pt3dadd(3.817,407.911,-6.3,0.48)}
{pt3dadd(2.115,411.382,-6.3,0.48)}
{pt3dadd(2.115,411.608,-6.3,0.48)}
{pt3dadd(1.064,420.307,-0.05,0.48)}
{pt3dadd(-0.426,420.746,-0.55,0.48)}
{pt3dadd(-0.426,421.184,-0.55,0.48)}
{pt3dadd(-0.426,425.307,-1.05,0.48)}
{pt3dadd(-4.229,430.973,-1.05,0.48)}
{pt3dadd(-7.408,440.11,4.95,0.48)}
{pt3dadd(-9.736,446.853,4.95,0.48)}
{pt3dadd(-13.34,450.976,4.45,0.48)}
{pt3dadd(-13.553,450.976,4.7,0.48)}
{pt3dadd(-17.569,457.294,5.95,0.48)}
{pt3dadd(-17.569,457.507,5.95,0.48)}
{pt3dadd(-18.218,463.469,6.140,0.48)}

{apical[18] connect apical[28](0), 1}
{access apical[28]}
{pt3dclear()}
{pt3dadd(1.277,177.741,0.7,1.44)}
{pt3dadd(1.21,177.143,33.25,0.48)}
{pt3dadd(-2.101,178.047,33.25,0.8)}
{pt3dadd(-2.633,180.614,34,0.8)}
{pt3dadd(-1.091,185.415,39.25,0.8)}
{pt3dadd(-0.904,185.655,40,0.8)}
{pt3dadd(-1.431,191.322,41.899,0.8)}