Calcium waves and mGluR-dependent synaptic plasticity in CA1 pyr. neurons (Ashhad & Narayanan 2013)

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Accession:150551
A morphologically realistic, conductance-based model equipped with kinetic schemes that govern several calcium signalling modules and pathways in CA1 pyramidal neurons
Reference:
1 . Ashhad S, Narayanan R (2013) Quantitative interactions between the A-type K+ current and inositol trisphosphate receptors regulate intraneuronal Ca2+ waves and synaptic plasticity. J Physiol 591:1645-69 [PubMed]
Citations  Citation Browser
Model Information (Click on a link to find other models with that property)
Model Type: Neuron or other electrically excitable cell; Synapse; Channel/Receptor; Dendrite;
Brain Region(s)/Organism: Hippocampus;
Cell Type(s): Hippocampus CA1 pyramidal GLU cell;
Channel(s): I Na,t; I L high threshold; I T low threshold; I A; I K; Ca pump;
Gap Junctions:
Receptor(s): AMPA; NMDA; mGluR; IP3;
Gene(s):
Transmitter(s): Glutamate;
Simulation Environment: NEURON;
Model Concept(s): Active Dendrites; Synaptic Plasticity; Signaling pathways; Calcium dynamics; G-protein coupled; Calcium waves;
Implementer(s): Narayanan, Rishikesh [rishi at iisc.ac.in]; Ashhad, Sufyan [soofy at mbu.iisc.ernet.in];
Search NeuronDB for information about:  Hippocampus CA1 pyramidal GLU cell; AMPA; NMDA; mGluR; IP3; I Na,t; I L high threshold; I T low threshold; I A; I K; Ca pump; Glutamate;
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AshhadNarayanan2013
Readme.html
cal4.mod
Calamp.mod
caltype.mod
camax.mod
cat.mod
ghknmda.mod
ip3dif.mod
kadist.mod *
kaprox.mod *
kdrca1.mod
mglur.mod
na3.mod
nax.mod *
Wghkampa.mod
CalciumWave.hoc
distance.hoc
Fig4F-G.hoc
Fig6C-F.hoc
mosinit.hoc
n123.hoc
n123_all.dis
n123_all.rdis
ObliquePath.hoc
oblique-paths.hoc
parameters.hoc
screenshot4F.png
screenshot4G.png
screenshot6C-F.png
                            
// This template creates the Basal Path lists, starting from the
// section attached to the trunk and ending with the basal tip section 
// written by Terrence Brannon, modified by Yiota Poirazi, July 2001, poirazi@LNC.usc.edu

begintemplate ObliquePath

public dtrunk_to_tip, trunk_section, root_oblique

strdef sexec

objref trunk_section
strdef trunk_section_name

objref root_oblique
strdef root_oblique_name

objref tip_section
strdef tip_section_name

objref oblique_path

proc init () {
  sec_count=0

  forsec $o1 {

    if (sec_count==1) {
       root_oblique    = new SectionRef()
       root_oblique_name=secname()
    }
      
    if (!sec_count) {
       distance(0,1)
       trunk_section  = new SectionRef()
       trunk_section_name=secname()
      }
    sec_count=sec_count+1

    tip_section    = new SectionRef()
    tip_section_name=secname()
  }

  access root_oblique.sec
  distance(0,0)
  access tip_section.sec
  dtrunk_to_tip=distance(1,1)

//  printf("ObliquePath trunk_section: %s root_oblique: %s tip_section: %s distance between root_oblique and tip_section: %g\n", trunk_section_name, root_oblique_name, tip_section_name, dtrunk_to_tip)
}

endtemplate ObliquePath