Olfactory bulb microcircuits model with dual-layer inhibition (Gilra & Bhalla 2015)

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Accession:153574
A detailed network model of the dual-layer dendro-dendritic inhibitory microcircuits in the rat olfactory bulb comprising compartmental mitral, granule and PG cells developed by Aditya Gilra, Upinder S. Bhalla (2015). All cell morphologies and network connections are in NeuroML v1.8.0. PG and granule cell channels and synapses are also in NeuroML v1.8.0. Mitral cell channels and synapses are in native python.
Reference:
1 . Gilra A, Bhalla US (2015) Bulbar microcircuit model predicts connectivity and roles of interneurons in odor coding. PLoS One 10:e0098045 [PubMed]
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Model Information (Click on a link to find other models with that property)
Model Type: Realistic Network;
Brain Region(s)/Organism: Olfactory bulb;
Cell Type(s): Olfactory bulb main mitral GLU cell; Olfactory bulb main interneuron periglomerular GABA cell; Olfactory bulb main interneuron granule MC GABA cell;
Channel(s): I A; I h; I K,Ca; I Sodium; I Calcium; I Potassium;
Gap Junctions:
Receptor(s): AMPA; NMDA; Gaba;
Gene(s):
Transmitter(s): Gaba; Glutamate;
Simulation Environment: Python; MOOSE/PyMOOSE;
Model Concept(s): Sensory processing; Sensory coding; Markov-type model; Olfaction;
Implementer(s): Bhalla, Upinder S [bhalla at ncbs.res.in]; Gilra, Aditya [aditya_gilra -at- yahoo -period- com];
Search NeuronDB for information about:  Olfactory bulb main mitral GLU cell; Olfactory bulb main interneuron periglomerular GABA cell; Olfactory bulb main interneuron granule MC GABA cell; AMPA; NMDA; Gaba; I A; I h; I K,Ca; I Sodium; I Calcium; I Potassium; Gaba; Glutamate;
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    <meta:notes>Inhibitory PG to mitral synpase taken same as since sIPSPs are same for PGs and granules as per Dong et al 2007</meta:notes>
     
    <synapse_type name="PG_mitral">
               
        <status value="in_progress">
            <meta:contributor>
                <meta:name>Aditya Gilra</meta:name>
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        <meta:notes> Dual exponential inhibitory PG to mitral synapse </meta:notes>
        
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            <meta:modelAuthor>
                <meta:name>Aditya Gilra</meta:name>
            </meta:modelAuthor>
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                <meta:name>Aditya Gilra</meta:name>
                <meta:institution>NCBS, India</meta:institution>    
                <meta:email>adityag@ncbs.res.in</meta:email>
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        <meta:publication>
           <meta:fullTitle>Hong-Wei Dong, Abdallah Hayar, and Matthew Ennis, “Activation of Group I Metabotropic Glutamate Receptors on Main Olfactory Bulb Granule Cells and Periglomerular Cells Enhances Synaptic Inhibition of Mitral Cells,” The Journal of neuroscience : the official journal of the Society for Neuroscience 27, no. 21 (May 23, 2007): 5654-5663.</meta:fullTitle>
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