Pyramidal neuron, fast, regular, and irregular spiking interneurons (Konstantoudaki et al 2014)

 Download zip file   Auto-launch 
Help downloading and running models
Accession:168310
This is a model network of prefrontal cortical microcircuit based primarily on rodent data. It includes 16 pyramidal model neurons, 2 fast spiking interneuron models, 1 regular spiking interneuron model and 1 irregular spiking interneuron model. The goal of the paper was to use this model network to determine the role of specific interneuron subtypes in persistent activity
Reference:
1 . Konstantoudaki X, Papoutsi A, Chalkiadaki K, Poirazi P, Sidiropoulou K (2014) Modulatory effects of inhibition on persistent activity in a cortical microcircuit model. Front Neural Circuits 8:7 [PubMed]
Citations  Citation Browser
Model Information (Click on a link to find other models with that property)
Model Type: Realistic Network; Neuron or other electrically excitable cell;
Brain Region(s)/Organism:
Cell Type(s): Neocortex fast spiking (FS) interneuron; Neocortex spiking regular (RS) neuron; Neocortex spiking low threshold (LTS) neuron; Neocortex spiking irregular interneuron;
Channel(s): I Na,p; I Na,t; I L high threshold; I T low threshold; I A; I K; I h; I_Ks; I_KD;
Gap Junctions:
Receptor(s): GabaA; GabaB; AMPA; NMDA;
Gene(s):
Transmitter(s): Gaba; Glutamate;
Simulation Environment: NEURON;
Model Concept(s): Activity Patterns; Synchronization; Active Dendrites;
Implementer(s): Sidiropoulou, Kyriaki [sidirop at imbb.forth.gr]; Konstantoudaki, Xanthippi [xeniakons at gmail.com];
Search NeuronDB for information about:  GabaA; GabaB; AMPA; NMDA; I Na,p; I Na,t; I L high threshold; I T low threshold; I A; I K; I h; I_Ks; I_KD; Gaba; Glutamate;
 
/
KonstantoudakiEtAl2014
experiment
data
ampa.mod
ampain.mod
cadyn.mod
cadynin.mod
cal.mod
calc.mod
calcb.mod
can.mod
cancr.mod
canin.mod
car.mod
cat.mod
catcb.mod
gabaa.mod *
gabaain.mod
gabab.mod
h.mod
hcb.mod
hin.mod
ican.mod
iccb.mod
iccr.mod
icin.mod
iks.mod
ikscb.mod
ikscr.mod *
iksin.mod
kadist.mod
kadistcr.mod
kadistin.mod
kaprox.mod
kaproxcb.mod
kaproxin.mod
kca.mod
kcain.mod
kct.mod
kctin.mod
kdr.mod *
kdrcb.mod
kdrcr.mod *
kdrin.mod
naf.mod
nafcb.mod
nafcr.mod *
nafin.mod
nafx.mod
nap.mod *
netstim.mod *
NMDA.mod
NMDAIN.mod
sinclamp.mod *
cb.hoc
cr.hoc
ExperimentControl.hoc *
final.hoc
incell.hoc
net.hoc
pfc_pc_temp.hoc
run
run_orig
                            
File not selected

<- Select file from this column.