Axon-somatic back-propagation in a detailed model of cat spinal motoneuron (Balbi et al, 2015)

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Accession:180370
Morphologically detailed conductance-based models of cat spinal alpha motoneurons have been developed, with the aim to reproduce and clarify some aspects of the electrophysiological behavior of the antidromic axon-somatic spike propagation. Fourteen 3D morphologically detailed somata and dendrites of cat spinal alpha motoneurons have been imported from an open-access web-based database of neuronal morphologies, NeuroMorpho.org, and instantiated in neurocomputational models.
Reference:
1 . Balbi P, Martinoia S, Massobrio P (2015) Axon-somatic back-propagation in detailed models of spinal alpha motoneurons. Front Comput Neurosci 9:15 [PubMed]
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Model Information (Click on a link to find other models with that property)
Model Type: Neuron or other electrically excitable cell;
Brain Region(s)/Organism: Spinal motoneuron;
Cell Type(s): Spinal cord lumbar motor neuron alpha ACh cell;
Channel(s): I Na,p; I Na,t; I K; I h; I K,Ca; I Calcium;
Gap Junctions:
Receptor(s):
Gene(s):
Transmitter(s):
Simulation Environment: NEURON;
Model Concept(s):
Implementer(s): Balbi, Pietro [piero.balbi at fsm.it];
Search NeuronDB for information about:  Spinal cord lumbar motor neuron alpha ACh cell; I Na,p; I Na,t; I K; I h; I K,Ca; I Calcium;
create AH
create IS

IS {
	nseg = 9
	diam = 3.0
	L = 50
	Ra = 70
	cm = 1
	
	insert pas
		g_pas = 0.0044
		e_pas = -72
	insert na3rp
		gbar_na3rp = 0.3 // original value 0.65
		sh_na3rp = 0	 // original value 5
		ar_na3rp = 0.4
	insert naps
		gbar_naps = 0.01 // original value 0.013
		sh_naps = 15	 // original value 0
		ar_naps = 0.4
	insert kdrRL
		gMax_kdrRL = 0.4 // original value 0.4
	insert extracellular xraxial=1e9 xg=1e10 xc=0
}

AH {
	nseg = 7
	diam(0:1) = soma.diam:IS.diam
	L = 25
	Ra = 70
	cm = 1

	insert pas
		g_pas = 0.0044
		e_pas = -72
	insert na3rp
		gbar_na3rp(0:1) = 0.015:0.3  //
		sh_na3rp = 0
		ar_na3rp = 0.4
	insert naps
		gbar_naps(0:1) = 0.002:0.01  //
		sh_naps = 15
		ar_naps = 0.4
	insert kdrRL
		gMax_kdrRL(0:1) = 0.035:0.4    //
	insert extracellular xraxial=1e9 xg=1e10 xc=0
}

connect IS(0), AH(1)