Modeling hebbian and homeostatic plasticity (Toyoizumi et al. 2014)

 Download zip file 
Help downloading and running models
Accession:180791
"... We propose a model in which synaptic strength is the product of a synapse-specific Hebbian factor and a postsynaptic- cell-specific homeostatic factor, with each factor separately arriving at a stable inactive state. This model captures ODP dynamics and has plausible biophysical substrates. We confirm model predictions experimentally that plasticity is inactive at stable states and that synaptic strength overshoots during recovery from visual deprivation. ..."
Reference:
1 . Toyoizumi T, Kaneko M, Stryker MP, Miller KD (2014) Modeling the dynamic interaction of Hebbian and homeostatic plasticity. Neuron 84:497-510 [PubMed]
Citations  Citation Browser
Model Information (Click on a link to find other models with that property)
Model Type: Realistic Network;
Brain Region(s)/Organism:
Cell Type(s): Neocortex L2/3 pyramidal GLU cell;
Channel(s):
Gap Junctions:
Receptor(s):
Gene(s):
Transmitter(s):
Simulation Environment: MATLAB;
Model Concept(s): Development; Homeostasis; Hebbian plasticity;
Implementer(s):
Search NeuronDB for information about:  Neocortex L2/3 pyramidal GLU cell;
 
/
Toyoizumi_etal_2014
readme.html
screenshot.png
twofm.m
                            
File not selected

<- Select file from this column.