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Multiplication by NMDA receptors in Direction Selective Ganglion cells (Poleg-Polsky & Diamond 2016)
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The model demonstrates how signal amplification with NMDARs depends on the synaptic environment. When direction selectivity (DS) detection is mediated by DS inhibition, NMDARs multiply other synaptic conductances. In the case of DS tuned excitation, NMDARs contribute additively.
Poleg-Polsky A, Diamond JS (2016) NMDA Receptors Multiplicatively Scale Visual Signals and Enhance Directional Motion Discrimination in Retinal Ganglion Cells.
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Neuron or other electrically excitable cell;
Retina ganglion GLU cell;
Polsky, Alon [alonpol at tx.technion.ac.il];
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Retina ganglion GLU cell
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