Muscle spindle feedback circuit (Moraud et al, 2016)

 Download zip file 
Help downloading and running models
Accession:189786
Here, we developed a computational model of the muscle spindle feedback circuits of the rat ankle that predicts the interactions between Epidural Stimulation and spinal circuit dynamics during gait.
Reference:
1 . Moraud EM, Capogrosso M, Formento E, Wenger N, DiGiovanna J, Courtine G, Micera S (2016) Mechanisms Underlying the Neuromodulation of Spinal Circuits for Correcting Gait and Balance Deficits after Spinal Cord Injury. Neuron 89:814-28 [PubMed]
Citations  Citation Browser
Model Information (Click on a link to find other models with that property)
Model Type: Realistic Network;
Brain Region(s)/Organism: Spinal motoneuron;
Cell Type(s): Spinal cord motor neuron slow twitch;
Channel(s): I K; I K,Ca; I Na,p; I Sodium;
Gap Junctions:
Receptor(s):
Gene(s):
Transmitter(s):
Simulation Environment: NEURON; Python;
Model Concept(s): Sensory processing; Neuromodulation;
Implementer(s): Capogrosso, Marco ; Formento, Emanuele ;
Search NeuronDB for information about:  I Na,p; I K; I K,Ca; I Sodium;
/
neuralnetwork
Info
diamdend_rat
lengthdend
                            
   1.5277386855568675e+01   1.7434194411648960e+01   1.9770735930735935e+01   1.7973396300669030e+01   1.7613928374655650e+01   1.6355790633608819e+01   1.4378717040535225e+01   1.2940845336481701e+01   1.0424569854388038e+01   8.5373632428177881e+00   6.7400236127508864e+00   3.1453443526170801e+00