Advanced search
User account
Login
Register
Find models by
Model name
First author
Each author
Find models for
Brain region
Concept
Find models of
Realistic Microcircuits
Connectionist Networks
Signaling pathways underlying LTP in hippocampal CA1 pyramidal cells (Jedrzejewska-Szmek et al 2017)
 
Download zip file
Help downloading and running models
Model Information
Model File
Versions
Accession:
190304
" ...We investigated whether the diverse experimental evidence can be unified by creating a spatial, mechanistic model of multiple signaling pathways in hippocampal CA1 neurons. Our results show that the combination of activity of several key kinases can predict the occurrence of long-lasting forms of LTP for multiple experimental protocols. ..."
Reference:
1 .
J?drzejewska-Szmek J, Luczak V, Abel T, Blackwell KT (2017) ß-adrenergic signaling broadly contributes to LTP induction.
PLoS Comput Biol
13
:e1005657
[
PubMed
]
Citations
Citation Browser
Model Information
(Click on a link to find other models with that property)
Model Type:
Synapse;
Brain Region(s)/Organism:
Cell Type(s):
Hippocampus CA1 pyramidal GLU cell;
Channel(s):
Gap Junctions:
Receptor(s):
Gene(s):
Transmitter(s):
Ephinephrine;
Simulation Environment:
NeuroRD;
Model Concept(s):
Long-term Synaptic Plasticity;
Signaling pathways;
Implementer(s):
Blackwell, Avrama [avrama at gmu.edu];
Jedrzejewska-Szmek, Joanna ;
Search NeuronDB
for information about:
Hippocampus CA1 pyramidal GLU cell
;
Ephinephrine
;
/
PLoSCompBiol2017
scripts
2_panel_signatures.py
4_panel_figure.py
check_thresholds.py
check_thresholds_1.5.py
check_thresholds_1.5_active_pka.py
check_thresholds_2.0.py
check_thresholds_dendrite.py
check_thresholds_dendrite_1.5.py
check_thresholds_dendrite_2.0.py
comp_av_traces_neurogranin.py
config.py
config_10.py
config_15.py
config_20.py
config_long.py
Epac_comparison.py
extract.py
fig_12.py
figures_formatting.py
functions.py
get_initial_specie_information.py
glurs_2_panel.py
make_average.py
make_figures.py
make_full_spines.py
merge_for_statistics.py
multispine_statistics.py
new_way_spines.py
propranolol_carvedilol.py
stochdiff2.1.10.jar
synaptic_tags_camkii_calibration_standard_paradigms_only_epac.py
File not selected
<- Select file from this column.