Geometry-induced features of current transfer in neuronal dendrites (Korogod, Kulagina 1998)

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Accession:19214
The impact of dendritic geometry on somatopetal transfer of the current generated by steady uniform activation of excitatory synaptic conductance distributed over passive, or active (Hodgkin-Huxley type), dendrites was studied in simulated neurons.
Reference:
1 . Korogod SM, Kulagina IB (1998) Geometry-induced features of current transfer in neuronal dendrites with tonically activated conductances. Biol Cybern 79:231-40 [PubMed]
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Model Information (Click on a link to find other models with that property)
Model Type: Dendrite;
Brain Region(s)/Organism:
Cell Type(s):
Channel(s): I Na,t; I K;
Gap Junctions:
Receptor(s):
Gene(s):
Transmitter(s):
Simulation Environment: NEURON;
Model Concept(s): Active Dendrites; Influence of Dendritic Geometry;
Implementer(s): Korogod, Sergey M [Korogod at ff.dsu.dp.ua]; Kulagina, Irina B [Kulagina at ff.dsu.dp.ua]; Kukushka, Valery I [Valery at ff.dsu.dp.ua];
Search NeuronDB for information about:  I Na,t; I K;
TITLE passive extrasynaptic (i) and synaptic (is) membrane channels 

COMMENT
Both "i" and "is" currents are switched on.
Replicas of NEURON pas.mod membrane mechanism 
for simulation of tonic activation of voltage-independent synaptic 
conductance as excitatory input to passive dendrites.
Reference: Korogod SM and Kulagina IB (1998) Biol Cybern 79:231-240
ENDCOMMENT


UNITS {
   (mV) = (millivolt)
   (mA) = (milliamp)
}

INDEPENDENT { v FROM -100 TO 50 WITH 50   (mV) }

NEURON {
   SUFFIX PasD
   NONSPECIFIC_CURRENT i, is
   RANGE g, erev, gs, es
}

PARAMETER {
   g = 0.0000677254 (mho/cm2)
   erev = -65       (mV)
   gs = 0.0000677254 (mho/cm2)
   es = 0.          (mV)
}

ASSIGNED { i (mA/cm2) is (mA/cm2) }

BREAKPOINT {
   i = g*(v - erev)
   is = gs*(v - es)
}