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Spikelet generation and AP initiation in a L5 neocortical pyr neuron (Michalikova et al. 2017) Fig 1
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The article by Michalikova et al. (2017) explores the generation of spikelets in cortical pyramidal neurons. The model cell, adapted from Hu et al. (2009), is a layer V pyramidal neuron. The cell is stimulated by fluctuating synaptic inputs and generates somatic APs and spikelets in response. The spikelets are initiated as APs at the AIS that do not activate the soma.
Michalikova M, Remme MW, Kempter R (2017) Spikelets in Pyramidal Neurons: Action Potentials Initiated in the Axon Initial Segment That Do Not Activate the Soma.
PLoS Comput Biol
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Neuron or other electrically excitable cell;
Neocortex L5/6 pyramidal GLU cell;
Action Potential Initiation;
Axonal Action Potentials;
Michalikova, Martina [tinka.michalikova at gmail.com];
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Neocortex L5/6 pyramidal GLU cell
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