A model for recurrent spreading depolarizations (Conte et al. 2017)

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Accession:235377
A detailed biophysical model for a neuron/astrocyte network is developed in order to explore mechanisms responsible for cortical spreading depolarizations. This includes a model for the Na+-glutamate transporter, which allows for a detailed description of reverse glutamate uptake. In particular, we consider the specific roles of elevated extracellular glutamate and K+ in the initiation, propagation and recurrence of spreading depolarizations.
Reference:
1 . Conte C, Lee R, Sarkar M, Terman D (2018) A mathematical model of recurrent spreading depolarizations. J Comput Neurosci 44:203-217 [PubMed]
Citations  Citation Browser
Model Information (Click on a link to find other models with that property)
Model Type: Extracellular; Glia; Neuron or other electrically excitable cell;
Brain Region(s)/Organism:
Cell Type(s): Astrocyte;
Channel(s): I K; I Na,p; I Cl, leak; Na/K pump; Na+-glutamate transporter;
Gap Junctions:
Receptor(s): Glutamate;
Gene(s):
Transmitter(s): Glutamate;
Simulation Environment: XPP;
Model Concept(s): Detailed Neuronal Models; Potassium buffering; Spreading depression; Spreading depolarization;
Implementer(s): Terman, David [terman at math.ohio-state.edu];
Search NeuronDB for information about:  Glutamate; I Na,p; I K; Na/K pump; I Cl, leak; Na+-glutamate transporter; Glutamate;
## Set file for waves.ode on Wed Dec 13 16:56:34 2017
475   Number of equations and auxiliaries
99   Number of parameters
# Numerical stuff
1    nout
40    nullcline mesh
8   Qual RK
700000  total
0.5  DeltaT
0  T0
0  Transient
500000  Bound
1e-12  DtMin
1  DtMax
1e-07  Tolerance
0.001  Abs. Tolerance
0  Max Delay
100   Eigenvector iterates
0.001  Eigenvector tolerance
0.001  Newton tolerance
0  Poincare plane
1e-05  Boundary value tolerance
1e-05  Boundary value epsilon
20   Boundary value iterates
0   Poincare None
1   Poincare variable
1   Poincare sign
0   Stop on Section
0   Delay flag
750000  Current time
750000  Last Time
1   MyStart
1   INFLAG
# Delays
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# Bndry conds
0
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# Old ICs
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111.9434002304703  CLE1
112.005261729019  CLE2
112.1136150685483  CLE3
112.2407561504239  CLE4
112.3544311384521  CLE5
112.4228323986848  CLE6
112.4660618611193  CLE7
112.4926735387137  CLE8
112.5061902159948  CLE9
112.5077562375851  CLE10
112.5040576667617  CLE11
112.4970910428431  CLE12
112.4872146924004  CLE13
112.4741641791422  CLE14
112.4573542999712  CLE15
112.4417855132757  CLE16
112.4270803873521  CLE17
112.4127317277664  CLE18
112.3981940217449  CLE19
112.3829081946141  CLE20
112.3708353426151  CLE21
112.3616295775303  CLE22
112.3549917874695  CLE23
112.3506934367282  CLE24
112.3485822008128  CLE25
11.06548834300281  CLI1
11.04147159869318  CLI2
10.99509970999435  CLI3
10.92928974196332  CLI4
10.8472799530739  CLI5
10.76756297010909  CLI6
10.68635783600407  CLI7
10.60134166790974  CLI8
10.51074876259932  CLI9
10.41300861585887  CLI10
10.31966841177049  CLI11
10.22887384910408  CLI12
10.13904456226816  CLI13
10.04869410662397  CLI14
9.956361066302048  CLI15
9.87217654945343  CLI16
9.794746826046083  CLI17
9.722810676041968  CLI18
9.655199097103052  CLI19
9.590812811326247  CLI20
9.538684500554705  CLI21
9.497964623071795  CLI22
9.467992338881766  CLI23
9.448279345485359  CLI24
9.438503069627011  CLI25
0.006901263872109097  GLUT1
0.006764746921707476  GLUT2
0.006486155172455111  GLUT3
0.006053623339712049  GLUT4
0.005447325447860024  GLUT5
0.004915561234142769  GLUT6
0.004428356176672852  GLUT7
0.003954953088663835  GLUT8
0.003461729510789283  GLUT9
0.002908858931251068  GLUT10
0.002492245885712076  GLUT11
0.002165626990975803  GLUT12
0.001886689094985009  GLUT13
0.001613746695065027  GLUT14
0.001299677870510725  GLUT15
0.00110156765059895  GLUT16
0.000969831401863086  GLUT17
0.000865937801203858  GLUT18
0.0007554879753921818  GLUT19
0.0005974457286252801  GLUT20
0.0005209913359418138  GLUT21
0.0004853991405922308  GLUT22
0.000469317216029485  GLUT23
0.000462358668960383  GLUT24
0.0004597876776447545  GLUT25
2.563206634359876  CAE1
2.610656235687419  CAE2
2.694285018269603  CAE3
2.793149397323013  CAE4
2.882939092779575  CAE5
2.929865271590241  CAE6
2.956420247104304  CAE7
2.972660847021472  CAE8
2.98322923423622  CAE9
2.990326308409001  CAE10
2.993620703664478  CAE11
2.995404454489318  CAE12
2.996532062543286  CAE13
2.997369801015053  CAE14
2.998087039560811  CAE15
2.99843891977839  CAE16
2.99863939111312  CAE17
2.998780894467349  CAE18
2.998914705759137  CAE19
2.999078417568022  CAE20
2.999150480394781  CAE21
2.999183655873471  CAE22
2.999199341421431  CAE23
2.999206694200963  CAE24
2.99920963856331  CAE25
0.01259174208522816  CAI1
0.01258940090167946  CAI2
0.01258525860801521  CAI3
0.01258032047947418  CAI4
0.01257576366664032  CAI5
0.01257335955929822  CAI6
0.01257197775411359  CAI7
0.01257111147834901  CAI8
0.01257052479561562  CAI9
0.01257010458044705  CAI10
0.01256990413488366  CAI11
0.01256979231978415  CAI12
0.01256971832216624  CAI13
0.01256965875549075  CAI14
0.01256960061359897  CAI15
0.01256957210622672  CAI16
0.0125695556261211  CAI17
0.01256954340307815  CAI18
0.01256953066758527  CAI19
0.01256951258816666  CAI20
0.01256950494891637  CAI21
0.01256950140742617  CAI22
0.0125694996433503  CAI23
0.01256949875072843  CAI24
0.01256949836856271  CAI25
0.9754351457073264  HER1
0.9754396007463093  HER2
0.9754474832123731  HER3
0.9754568802525617  HER4
0.97546555183003  HER5
0.9754701268903372  HER6
0.9754727565142645  HER7
0.9754744050785623  HER8
0.9754755215704085  HER9
0.9754763212690667  HER10
0.9754767027319915  HER11
0.9754769155249627  HER12
0.9754770563485815  HER13
0.9754771697092076  HER14
0.9754772803586684  HER15
0.9754773346108867  HER16
0.9754773659740963  HER17
0.9754773892357294  HER18
0.9754774134726387  HER19
0.9754774478796266  HER20
0.9754774624178999  HER21
0.9754774691577164  HER22
0.9754774725149323  HER23
0.9754774742136836  HER24
0.9754774749409846  HER25
10.01155796933342  CAER1
10.01045336825744  CAER2
10.00849640100557  CAER3
10.00613784420224  CAER4
10.00389381427755  CAER5
10.00268799530732  CAER6
10.00196969851702  CAER7
10.00149487293088  CAER8
10.00114876709765  CAER9
10.00087564060483  CAER10
10.00074030458687  CAER11
10.00066190861656  CAER12
10.00060734034286  CAER13
10.00056001960576  CAER14
10.00050913451469  CAER15
10.00048416594067  CAER16
10.00046959031945  CAER17
10.00045844981772  CAER18
10.00044622157718  CAER19
10.00042769291696  CAER20
10.00041998967197  CAER21
10.00041641076167  CAER22
10.00041459324492  CAER23
10.00041364899179  CAER24
10.00041323609157  CAER25
# Ending  ICs
-67.7317426603539  V1
-67.83356658594188  V2
-68.01822150040233  V3
-68.25151446971802  V4
-68.49423670619552  V5
-68.67386498737822  V6
-68.8303648753848  V7
-68.98203165976126  V8
-69.13844136443346  V9
-69.30537444425218  V10
-69.46214154192431  V11
-69.61540761701933  V12
-69.76927270216284  V13
-69.92701108703343  V14
-70.09150930824077  V15
-70.23989225983605  V16
-70.37452813252881  V17
-70.49751043718153  V18
-70.61102289167452  V19
-70.71774123305124  V20
-70.79672755085682  V21
-70.85255654902507  V22
-70.89023188019908  V23
-70.91396378242875  V24
-70.92573593035922  V25
0.2871203675523505  N1
0.2856340015914086  N2
0.2829503344642936  N3
0.2795817082210875  N4
0.2761030988059825  N5
0.2735460371971977  N6
0.2713302878625791  N7
0.2691937451322443  N8
0.2670015505523288  N9
0.2646744211772109  N10
0.2625008666806307  N11
0.2603869994379097  N12
0.2582759962596115  N13
0.2561234645711749  N14
0.253891252963345  N15
0.2518887643692975  N16
0.2500808869760152  N17
0.2484370683965132  N18
0.246926259778768  N19
0.2455115211733248  N20
0.2444679468517151  N21
0.2437321416731201  N22
0.2432364441440907  N23
0.2429245529532015  N24
0.2427699409590363  N25
0.9736503247373246  HP1
0.9738489942682614  HP2
0.9742134253288137  HP3
0.9746860155627579  HP4
0.9752028283791589  HP5
0.9756020834676769  HP6
0.9759705554272016  HP7
0.9763489808692242  HP8
0.9767594591788122  HP9
0.9772154423483942  HP10
0.9776431999236128  HP11
0.9780603333273954  HP12
0.9784783815018809  HP13
0.9789066225273304  HP14
0.9793523365231732  HP15
0.9797404117813081  HP16
0.9800783621205703  HP17
0.9803727737262081  HP18
0.9806306584006983  HP19
0.9808614935584639  HP20
0.9810072153015191  HP21
0.9810888640993455  HP22
0.9811302197512675  HP23
0.9811516606089949  HP24
0.9811623204380965  HP25
0.01151154251879158  SG1
0.01011644282162774  SG2
0.00774608314337668  SG3
0.005078044206433986  SG4
0.002772932506456058  SG5
0.001662035002442434  SG6
0.001055406069256734  SG7
0.0006843251827417944  SG8
0.0004352645266244981  SG9
0.0002590084710302848  SG10
0.000178712210937718  SG11
0.0001354835894924726  SG12
0.0001075933462375924  SG13
8.548433318923825e-05  SG14
6.448848472574278e-05  SG15
5.473360132351462e-05  SG16
4.948803590692655e-05  SG17
4.580111822596076e-05  SG18
4.190935130150843e-05  SG19
3.630788775866188e-05  SG20
3.41120483744831e-05  SG21
3.325232055518372e-05  SG22
3.29279140738771e-05  SG23
3.281491853009553e-05  SG24
3.278196340808409e-05  SG25
-35.68064380996597  VA1
-35.6726082176832  VA2
-35.65400405326361  VA3
-35.62089355391679  VA4
-41.74067218857992  VA5
-41.71164224475277  VA6
-41.67744555283357  VA7
-41.63786474046376  VA8
-41.59299899797756  VA9
-46.36488293789211  VA10
-46.34769013402519  VA11
-46.32875143945883  VA12
-46.30896190592585  VA13
-46.28946536080417  VA14
-50.09682094270099  VA15
-50.10550203647762  VA16
-50.11090770162706  VA17
-50.11475282986599  VA18
-50.11903953696964  VA19
-53.1662455403031  VA20
-53.18376798039656  VA21
-53.19411927030018  VA22
-53.19953461833118  VA23
-53.20186165689698  VA24
-53.20258219226697  VA25
11.06635959582875  KE1
11.05277157318981  KE2
11.0266467636524  KE3
10.98966283040845  KE4
10.94349160010413  KE5
10.89422542202783  KE6
10.84170019089526  KE7
10.78531056741192  KE8
10.72427390083724  KE9
10.65773217185266  KE10
10.59300936650525  KE11
10.52905852358098  KE12
10.4648461925241  KE13
10.39935031064379  KE14
10.33155377324251  KE15
10.2697926410412  KE16
10.21301184634469  KE17
10.16017650227258  KE18
10.11024459256981  KE19
10.06214956283812  KE20
10.02411481984266  KE21
9.995101977179228  KE22
9.974195619428485  KE23
9.960664711733722  KE24
9.954018190000763  KE25
2.580673882365564  NAI1
2.571499808719672  NAI2
2.555000678887603  NAI3
2.534377569606046  NAI4
2.513241000604581  NAI5
2.49796692023073  NAI6
2.485405492857376  NAI7
2.474273621721973  NAI8
2.463991852128256  NAI9
2.454284186445838  NAI10
2.445629526369494  NAI11
2.437575849764002  NAI12
2.429935984403265  NAI13
2.42261993690232  NAI14
2.4155129110198  NAI15
2.408416539894618  NAI16
2.40101168242293  NAI17
2.39305642990813  NAI18
2.384387612958614  NAI19
2.375005539089563  NAI20
2.365121359486904  NAI21
2.355465983771135  NAI22
2.347142306086169  NAI23
2.341235103810869  NAI24
2.338272085816799  NAI25
134.5410770266724  NAE1
134.5608811372998  NAE2
134.5988712590484  NAE3
134.6524465346153  NAE4
134.7189879881014  NAE5
134.7897603521681  NAE6
134.8649674341895  NAE7
134.9455110161825  NAE8
135.0325802913661  NAE9
135.1274855579813  NAE10
135.2196877969173  NAE11
135.3107888194072  NAE12
135.4023772372434  NAE13
135.4960202933763  NAE14
135.5932566961794  NAE15
135.6819237051135  NAE16
135.7635906371358  NAE17
135.8398039276707  NAE18
135.9121041844952  NAE19
135.9820221946604  NAE20
136.0373929348046  NAE21
136.0796607298116  NAE22
136.1101239293991  NAE23
136.1298351368805  NAE24
136.1395134845392  NAE25
142.4521940463158  KI1
142.4914735637837  KI2
142.5622600761374  KI3
142.6479269890847  KI4
142.7242308722269  KI5
142.7520134954542  KI6
142.7525099770137  KI7
142.7360679159494  KI8
142.7075671498051  KI9
142.6690872559282  KI10
142.6261200802487  KI11
142.5810653993669  KI12
142.5341763739549  KI13
142.4849251001722  KI14
142.4328234833168  KI15
142.3853794143562  KI16
142.3431218116949  KI17
142.3060717627217  KI18
142.2739392951621  KI19
142.2460218937171  KI20
142.2280858580945  KI21
142.2178254466887  KI22
142.2122992606608  KI23
142.2090503677341  KI24
142.2072612535258  KI25
43.01570952752692  KIA1
42.95101400193553  KIA2
42.82161271531016  KIA3
42.62776449180514  KIA4
53.41512330508086  KIA5
53.12177010084434  KIA6
52.80316754577682  KIA7
52.45624971587923  KIA8
52.07778084356729  KIA9
61.90103751439992  KIA10
61.49369845347417  KIA11
61.08723401592282  KIA12
60.67790811288561  KIA13
60.26255894727267  KIA14
69.0566427799822  KIA15
68.67577386796523  KIA16
68.31880118250116  KIA17
67.98348671986602  KIA18
67.66815140698397  KIA19
75.49168765596468  KIA20
75.26257132845767  KIA21
75.07907265409162  KIA22
74.94098525364993  KIA23
74.84825607197979  KIA24
74.80150665000106  KIA25
88.9535604409767  NAIA1
89.01590455766716  NAIA2
89.13999647766988  NAIA3
89.32381036677441  NAIA4
78.61393021113146  NAIA5
78.8936183232875  NAIA6
79.20107949503034  NAIA7
79.53669309484977  NAIA8
79.90033227228953  NAIA9
70.13925474170271  NAIA10
70.5300038482214  NAIA11
70.92434667610459  NAIA12
71.32236672894298  NAIA13
71.72274809704936  NAIA14
62.97933352489097  NAIA15
63.34421504712716  NAIA16
63.69131633595813  NAIA17
64.0180306279118  NAIA18
64.32053724960113  NAIA19
56.53822291782552  NAIA20
56.75399289297938  NAIA21
56.93191814586817  NAIA22
57.06759695390431  NAIA23
57.15927088803893  NAIA24
57.20561317033484  NAIA25
124.6823177486805  CLE1
124.6386191059867  CLE2
124.5484892002927  CLE3
124.4093549465909  CLE4
124.222715190072  CLE5
124.0201371051044  CLE6
123.8107079850331  CLE7
123.5965410133222  CLE8
123.3775141886073  CLE9
123.1525825108387  CLE10
122.9360717614417  CLE11
122.7266412588586  CLE12
122.5229541477775  CLE13
122.3238035728987  CLE14
122.1276250549868  CLE15
121.9411592772654  CLE16
121.7617256090355  CLE17
121.58708811284  CLE18
121.4157973179875  CLE19
121.2478824238704  CLE20
121.0918760805326  CLE21
120.9536379973968  CLE22
120.8413149940705  CLE23
120.7629138264685  CLE24
120.7231028472675  CLE25
10.44872091088436  CLI1
10.42717890621399  CLI2
10.38576079775867  CLI3
10.32778550401221  CLI4
10.25769053846329  CLI5
10.19353492206298  CLI6
10.13005248319418  CLI7
10.06426629790953  CLI8
9.994230220524106  CLI9
9.918479496590852  CLI10
9.84620153558156  CLI11
9.775659598175368  CLI12
9.705567919609303  CLI13
9.634813186270934  CLI14
9.562395615076831  CLI15
9.496952467839384  CLI16
9.437565688239877  CLI17
9.383413797755736  CLI18
9.333683483337797  CLI19
9.287429224238847  CLI20
9.251819792099566  CLI21
9.225316621147226  CLI22
9.206347468631442  CLI23
9.193773069729335  CLI24
9.187347054109159  CLI25
0.006263910384415394  GLUT1
0.006130396237369248  GLUT2
0.005856113801510208  GLUT3
0.00542569040793377  GLUT4
0.004813670440252011  GLUT5
0.004298451135051284  GLUT6
0.00384250491099685  GLUT7
0.003408139326020292  GLUT8
0.002954909832462539  GLUT9
0.002435285564808523  GLUT10
0.002063958886596562  GLUT11
0.001786901472794068  GLUT12
0.001556324788161621  GLUT13
0.001326231625787073  GLUT14
0.00104432117111439  GLUT15
0.0008802822294859985  GLUT16
0.0007795190156395822  GLUT17
0.0007020850351480878  GLUT18
0.000613273417958434  GLUT19
0.0004697822522034757  GLUT20
0.00040739103766456  GLUT21
0.000381862215619997  GLUT22
0.0003720573562806058  GLUT23
0.0003686194730448606  GLUT24
0.0003676145811632865  GLUT25
2.869028744081061  CAE1
2.884164809504087  CAE2
2.910159821146594  CAE3
2.939938903639372  CAE4
2.966299905874688  CAE5
2.979130723703704  CAE6
2.986247068353885  CAE7
2.990705307920087  CAE8
2.993802761425094  CAE9
2.996095683057832  CAE10
2.997154633167668  CAE11
2.997733409629119  CAE12
2.998116104926684  CAE13
2.9984321203313  CAE14
2.998748440059389  CAE15
2.998896220869003  CAE16
2.998976805673848  CAE17
2.999034870977035  CAE18
2.999097782645026  CAE19
2.999190584242234  CAE20
2.999227199241639  CAE21
2.99924204616238  CAE22
2.99924812093276  CAE23
2.999250579603814  CAE24
2.999251461221343  CAE25
0.01262598246147608  CAI1
0.01262336883838966  CAI2
0.01261864110293184  CAI3
0.01261277091634478  CAI4
0.01260702239763607  CAI5
0.01260367351009065  CAI6
0.01260150626039573  CAI7
0.01259994116965814  CAI8
0.01259869229149376  CAI9
0.01259761581456834  CAI10
0.01259683854589442  CAI11
0.01259619645089156  CAI12
0.01259562931244962  CAI13
0.01259511418388496  CAI14
0.01259463439986445  CAI15
0.01259424259794243  CAI16
0.01259389506271956  CAI17
0.01259356888152455  CAI18
0.01259325033088488  CAI19
0.01259292997870356  CAI20
0.01259265281010638  CAI21
0.01259241896939957  CAI22
0.01259223744000596  CAI23
0.01259211628542579  CAI24
0.0125920569695077  CAI25
0.9753699936285518  HER1
0.9753749662635174  HER2
0.9753839613392435  HER3
0.9753951303665566  HER4
0.9754060682346026  HER5
0.9754124404228319  HER6
0.975416564289465  HER7
0.9754195424009217  HER8
0.975421918837594  HER9
0.9754239672387698  HER10
0.9754254462969693  HER11
0.9754266681412789  HER12
0.9754277473547689  HER13
0.9754287276009682  HER14
0.9754296405916489  HER15
0.975430386161338  HER16
0.975431047496073  HER17
0.9754316681965673  HER18
0.9754322743774398  HER19
0.9754328839872701  HER20
0.9754334114222327  HER21
0.9754338564073568  HER22
0.9754342018474274  HER23
0.9754344323978175  HER24
0.9754345452727349  HER25
10.07068987432922  CAER1
10.06812034478478  CAER2
10.06335830045193  CAER3
10.05723618046813  CAER4
10.05100127217192  CAER5
10.04718441131046  CAER6
10.0446240267273  CAER7
10.04272090403842  CAER8
10.04116412536684  CAER9
10.03979098021881  CAER10
10.03876171354623  CAER11
10.03789290603432  CAER12
10.03711726198136  CAER13
10.03641011809962  CAER14
10.03575170675956  CAER15
10.03520820215058  CAER16
10.03472342604215  CAER17
10.03426745545212  CAER18
10.03382234561248  CAER19
10.03337597213341  CAER20
10.03298772238818  CAER21
10.03265939896959  CAER22
10.0324042587861  CAER23
10.03223389690527  CAER24
10.03215047329067  CAER25
# Parameters
8310  R
310  Temp
96485  F
1e-05  pna
2e-09  pnal
-34  thm
5  sigm
3e-08  pnap
10000  taubar
-40  thmp
6  sigmp
-48  thhp
-6  sighp
-49  vt
6  sig
0.05  phihp
6.999999999999999e-05  pk
4e-07  pkl
-55  thn
14  sgn
0.05  taun0
0.27  taun1
-40  thnt
-12  sn
0.8  phin
3e-06  pnmda
-10  thetat
2  trise
1  tdecay
0.5  alphan
3  pca
0.01  thg
0.001  sigmag
2e-07  pcl
5  imax
0.002  dk
0.001333  dna
0.0021  dg
1.5e-08  pnaa
6e-06  pka
0.08  imaxa1
0.08  imaxa2
0.08  imaxa3
0.08  imaxa4
0.12  imaxa5
0.12  imaxa6
0.12  imaxa7
0.12  imaxa8
0.12  imaxa9
0.16  imaxa10
0.16  imaxa11
0.16  imaxa12
0.16  imaxa13
0.16  imaxa14
0.2  imaxa15
0.2  imaxa16
0.2  imaxa17
0.2  imaxa18
0.2  imaxa19
0.24  imaxa20
0.24  imaxa21
0.24  imaxa22
0.24  imaxa23
0.24  imaxa24
0.24  imaxa25
0.5  hr
3e-05  gnagl
922  S
2160  voln
0.05  delta
1600  Sa
2000  vola
1e-05  gnab
140  na0
2e-05  gkb
4  k0
110  cl0
6e-06  gclb
1  glui0
0.001  glut0
3e-05  gcab
3  cae0
60  minute
1000  second
1  vg
0.5  pcytosol
75  dcytosol
0.1  per
1000  der
0.01  fi
3000  vip3
0.01  vleak
0.25  dip3
0.5  dinh
1  dact
4  tau
110  vserca
0.4  kserca
0.3  ip3
# Graphics
0.7071097251469876  rm
-0.4999999999826661  rm
0.4999958366025516  rm
0.7071038372138505  rm
0.5000041633974482  rm
-0.4999999999826661  rm
0  rm
0.7071038372138505  rm
0.7071097251469876  rm
0    
1    
1    
1    
0    
0    
10    
1    
1    
0    
0    
1    
1    
1    
0    
0    
1    
1    
1    
0    
0    
1    
1    
1    
0    
0    
1    
1    
1    
0    
0    
1    
1    
1    
0    
0    
1    
1    
1    
0    
0    
1    
1    
1    
0    
0    
1    
1    
1    
0    
-1000   
1000   
0    
0   3DFlag
1   Timeflag
0   Colorflag
0   Type
1  color scale
0   minscale
700000   xmax
0   xmin
0   ymax
-90   ymin
12   zmax
-12   zmin
350000   
2.857142857142857e-06   
-45   
0.02222222222222222   
0   
0.08333333333333333   
45   Theta
45   Phi
0    xshft
0    yshft
0    zshft
0   xlo
-90   ylo
0   
-80   
700000   xhi
0   yhi
50000   
0   
# Transpose variables etc
V1
2   n columns
1   n rows
1   row skip
1   col skip
1   row 0
# Coupling stuff for H funs
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
# Array plot stuff
v1
25   NCols
0   Row 1
1400000   NRows
1   RowSkip
-80  Zmin
-20  Zmax
# Torus information 
0    Torus flag 1=ON
6.283185307179586  Torus period
# Range information
R
-1   eq-range stab col
0   shoot flag 1=on
10   eq-range steps
0  eq_range low
1  eq_range high
V1
V1
20   Range steps
0   Cycle color 1=on
1   Reset data 1=on
1   Use old I.C.s 1=yes
0  Par1 low
0  Par2 low
1  Par1 high
1  Par2 high
R
0   BVP side
0   color cycle flag 1=on
10   BVP range steps
0  BVP range low
1  BVP range high
RHS etc ...
dV1/dT=-(INA(V1,N1,NAE1,NAI1)+INAP(V1,HP1,NAE1,NAI1)+IK(V1,N1,KE1,KI1)+ICL1+IPUMP1+INMDA1)
dV2/dT=-(INA(V2,N2,NAE2,NAI2)+INAP(V2,HP2,NAE2,NAI2)+IK(V2,N2,KE2,KI2)+ICL2+IPUMP2+INMDA2)
dV3/dT=-(INA(V3,N3,NAE3,NAI3)+INAP(V3,HP3,NAE3,NAI3)+IK(V3,N3,KE3,KI3)+ICL3+IPUMP3+INMDA3)
dV4/dT=-(INA(V4,N4,NAE4,NAI4)+INAP(V4,HP4,NAE4,NAI4)+IK(V4,N4,KE4,KI4)+ICL4+IPUMP4+INMDA4)
dV5/dT=-(INA(V5,N5,NAE5,NAI5)+INAP(V5,HP5,NAE5,NAI5)+IK(V5,N5,KE5,KI5)+ICL5+IPUMP5+INMDA5)
dV6/dT=-(INA(V6,N6,NAE6,NAI6)+INAP(V6,HP6,NAE6,NAI6)+IK(V6,N6,KE6,KI6)+ICL6+IPUMP6+INMDA6)
dV7/dT=-(INA(V7,N7,NAE7,NAI7)+INAP(V7,HP7,NAE7,NAI7)+IK(V7,N7,KE7,KI7)+ICL7+IPUMP7+INMDA7)
dV8/dT=-(INA(V8,N8,NAE8,NAI8)+INAP(V8,HP8,NAE8,NAI8)+IK(V8,N8,KE8,KI8)+ICL8+IPUMP8+INMDA8)
dV9/dT=-(INA(V9,N9,NAE9,NAI9)+INAP(V9,HP9,NAE9,NAI9)+IK(V9,N9,KE9,KI9)+ICL9+IPUMP9+INMDA9)
dV10/dT=-(INA(V10,N10,NAE10,NAI10)+INAP(V10,HP10,NAE10,NAI10)+IK(V10,N10,KE10,KI10)+ICL10+IPUMP10+INMDA10)
dV11/dT=-(INA(V11,N11,NAE11,NAI11)+INAP(V11,HP11,NAE11,NAI11)+IK(V11,N11,KE11,KI11)+ICL11+IPUMP11+INMDA11)
dV12/dT=-(INA(V12,N12,NAE12,NAI12)+INAP(V12,HP12,NAE12,NAI12)+IK(V12,N12,KE12,KI12)+ICL12+IPUMP12+INMDA12)
dV13/dT=-(INA(V13,N13,NAE13,NAI13)+INAP(V13,HP13,NAE13,NAI13)+IK(V13,N13,KE13,KI13)+ICL13+IPUMP13+INMDA13)
dV14/dT=-(INA(V14,N14,NAE14,NAI14)+INAP(V14,HP14,NAE14,NAI14)+IK(V14,N14,KE14,KI14)+ICL14+IPUMP14+INMDA14)
dV15/dT=-(INA(V15,N15,NAE15,NAI15)+INAP(V15,HP15,NAE15,NAI15)+IK(V15,N15,KE15,KI15)+ICL15+IPUMP15+INMDA15)
dV16/dT=-(INA(V16,N16,NAE16,NAI16)+INAP(V16,HP16,NAE16,NAI16)+IK(V16,N16,KE16,KI16)+ICL16+IPUMP16+INMDA16)
dV17/dT=-(INA(V17,N17,NAE17,NAI17)+INAP(V17,HP17,NAE17,NAI17)+IK(V17,N17,KE17,KI17)+ICL17+IPUMP17+INMDA17)
dV18/dT=-(INA(V18,N18,NAE18,NAI18)+INAP(V18,HP18,NAE18,NAI18)+IK(V18,N18,KE18,KI18)+ICL18+IPUMP18+INMDA18)
dV19/dT=-(INA(V19,N19,NAE19,NAI19)+INAP(V19,HP19,NAE19,NAI19)+IK(V19,N19,KE19,KI19)+ICL19+IPUMP19+INMDA19)
dV20/dT=-(INA(V20,N20,NAE20,NAI20)+INAP(V20,HP20,NAE20,NAI20)+IK(V20,N20,KE20,KI20)+ICL20+IPUMP20+INMDA20)
dV21/dT=-(INA(V21,N21,NAE21,NAI21)+INAP(V21,HP21,NAE21,NAI21)+IK(V21,N21,KE21,KI21)+ICL21+IPUMP21+INMDA21)
dV22/dT=-(INA(V22,N22,NAE22,NAI22)+INAP(V22,HP22,NAE22,NAI22)+IK(V22,N22,KE22,KI22)+ICL22+IPUMP22+INMDA22)
dV23/dT=-(INA(V23,N23,NAE23,NAI23)+INAP(V23,HP23,NAE23,NAI23)+IK(V23,N23,KE23,KI23)+ICL23+IPUMP23+INMDA23)
dV24/dT=-(INA(V24,N24,NAE24,NAI24)+INAP(V24,HP24,NAE24,NAI24)+IK(V24,N24,KE24,KI24)+ICL24+IPUMP24+INMDA24)
dV25/dT=-(INA(V25,N25,NAE25,NAI25)+INAP(V25,HP25,NAE25,NAI25)+IK(V25,N25,KE25,KI25)+ICL25+IPUMP25+INMDA25)
dN1/dT=PHIN*(NINF(V1)-N1)/TAUN(V1)
dN2/dT=PHIN*(NINF(V2)-N2)/TAUN(V2)
dN3/dT=PHIN*(NINF(V3)-N3)/TAUN(V3)
dN4/dT=PHIN*(NINF(V4)-N4)/TAUN(V4)
dN5/dT=PHIN*(NINF(V5)-N5)/TAUN(V5)
dN6/dT=PHIN*(NINF(V6)-N6)/TAUN(V6)
dN7/dT=PHIN*(NINF(V7)-N7)/TAUN(V7)
dN8/dT=PHIN*(NINF(V8)-N8)/TAUN(V8)
dN9/dT=PHIN*(NINF(V9)-N9)/TAUN(V9)
dN10/dT=PHIN*(NINF(V10)-N10)/TAUN(V10)
dN11/dT=PHIN*(NINF(V11)-N11)/TAUN(V11)
dN12/dT=PHIN*(NINF(V12)-N12)/TAUN(V12)
dN13/dT=PHIN*(NINF(V13)-N13)/TAUN(V13)
dN14/dT=PHIN*(NINF(V14)-N14)/TAUN(V14)
dN15/dT=PHIN*(NINF(V15)-N15)/TAUN(V15)
dN16/dT=PHIN*(NINF(V16)-N16)/TAUN(V16)
dN17/dT=PHIN*(NINF(V17)-N17)/TAUN(V17)
dN18/dT=PHIN*(NINF(V18)-N18)/TAUN(V18)
dN19/dT=PHIN*(NINF(V19)-N19)/TAUN(V19)
dN20/dT=PHIN*(NINF(V20)-N20)/TAUN(V20)
dN21/dT=PHIN*(NINF(V21)-N21)/TAUN(V21)
dN22/dT=PHIN*(NINF(V22)-N22)/TAUN(V22)
dN23/dT=PHIN*(NINF(V23)-N23)/TAUN(V23)
dN24/dT=PHIN*(NINF(V24)-N24)/TAUN(V24)
dN25/dT=PHIN*(NINF(V25)-N25)/TAUN(V25)
dHP1/dT=PHIHP*(HINFP(V1)-HP1)/TAUHP(V1)
dHP2/dT=PHIHP*(HINFP(V2)-HP2)/TAUHP(V2)
dHP3/dT=PHIHP*(HINFP(V3)-HP3)/TAUHP(V3)
dHP4/dT=PHIHP*(HINFP(V4)-HP4)/TAUHP(V4)
dHP5/dT=PHIHP*(HINFP(V5)-HP5)/TAUHP(V5)
dHP6/dT=PHIHP*(HINFP(V6)-HP6)/TAUHP(V6)
dHP7/dT=PHIHP*(HINFP(V7)-HP7)/TAUHP(V7)
dHP8/dT=PHIHP*(HINFP(V8)-HP8)/TAUHP(V8)
dHP9/dT=PHIHP*(HINFP(V9)-HP9)/TAUHP(V9)
dHP10/dT=PHIHP*(HINFP(V10)-HP10)/TAUHP(V10)
dHP11/dT=PHIHP*(HINFP(V11)-HP11)/TAUHP(V11)
dHP12/dT=PHIHP*(HINFP(V12)-HP12)/TAUHP(V12)
dHP13/dT=PHIHP*(HINFP(V13)-HP13)/TAUHP(V13)
dHP14/dT=PHIHP*(HINFP(V14)-HP14)/TAUHP(V14)
dHP15/dT=PHIHP*(HINFP(V15)-HP15)/TAUHP(V15)
dHP16/dT=PHIHP*(HINFP(V16)-HP16)/TAUHP(V16)
dHP17/dT=PHIHP*(HINFP(V17)-HP17)/TAUHP(V17)
dHP18/dT=PHIHP*(HINFP(V18)-HP18)/TAUHP(V18)
dHP19/dT=PHIHP*(HINFP(V19)-HP19)/TAUHP(V19)
dHP20/dT=PHIHP*(HINFP(V20)-HP20)/TAUHP(V20)
dHP21/dT=PHIHP*(HINFP(V21)-HP21)/TAUHP(V21)
dHP22/dT=PHIHP*(HINFP(V22)-HP22)/TAUHP(V22)
dHP23/dT=PHIHP*(HINFP(V23)-HP23)/TAUHP(V23)
dHP24/dT=PHIHP*(HINFP(V24)-HP24)/TAUHP(V24)
dHP25/dT=PHIHP*(HINFP(V25)-HP25)/TAUHP(V25)
dSG1/dT=-SG1/TDECAY+ALPHAN*SINFG(GLUT1)*(1-SG1)
dSG2/dT=-SG2/TDECAY+ALPHAN*SINFG(GLUT2)*(1-SG2)
dSG3/dT=-SG3/TDECAY+ALPHAN*SINFG(GLUT3)*(1-SG3)
dSG4/dT=-SG4/TDECAY+ALPHAN*SINFG(GLUT4)*(1-SG4)
dSG5/dT=-SG5/TDECAY+ALPHAN*SINFG(GLUT5)*(1-SG5)
dSG6/dT=-SG6/TDECAY+ALPHAN*SINFG(GLUT6)*(1-SG6)
dSG7/dT=-SG7/TDECAY+ALPHAN*SINFG(GLUT7)*(1-SG7)
dSG8/dT=-SG8/TDECAY+ALPHAN*SINFG(GLUT8)*(1-SG8)
dSG9/dT=-SG9/TDECAY+ALPHAN*SINFG(GLUT9)*(1-SG9)
dSG10/dT=-SG10/TDECAY+ALPHAN*SINFG(GLUT10)*(1-SG10)
dSG11/dT=-SG11/TDECAY+ALPHAN*SINFG(GLUT11)*(1-SG11)
dSG12/dT=-SG12/TDECAY+ALPHAN*SINFG(GLUT12)*(1-SG12)
dSG13/dT=-SG13/TDECAY+ALPHAN*SINFG(GLUT13)*(1-SG13)
dSG14/dT=-SG14/TDECAY+ALPHAN*SINFG(GLUT14)*(1-SG14)
dSG15/dT=-SG15/TDECAY+ALPHAN*SINFG(GLUT15)*(1-SG15)
dSG16/dT=-SG16/TDECAY+ALPHAN*SINFG(GLUT16)*(1-SG16)
dSG17/dT=-SG17/TDECAY+ALPHAN*SINFG(GLUT17)*(1-SG17)
dSG18/dT=-SG18/TDECAY+ALPHAN*SINFG(GLUT18)*(1-SG18)
dSG19/dT=-SG19/TDECAY+ALPHAN*SINFG(GLUT19)*(1-SG19)
dSG20/dT=-SG20/TDECAY+ALPHAN*SINFG(GLUT20)*(1-SG20)
dSG21/dT=-SG21/TDECAY+ALPHAN*SINFG(GLUT21)*(1-SG21)
dSG22/dT=-SG22/TDECAY+ALPHAN*SINFG(GLUT22)*(1-SG22)
dSG23/dT=-SG23/TDECAY+ALPHAN*SINFG(GLUT23)*(1-SG23)
dSG24/dT=-SG24/TDECAY+ALPHAN*SINFG(GLUT24)*(1-SG24)
dSG25/dT=-SG25/TDECAY+ALPHAN*SINFG(GLUT25)*(1-SG25)
dVA1/dT=-(IKA(VA1,KE1,KIA1)+INAA(VA1,NAE1,NAIA1)+IPUMPA(KE1,NAIA1,IMAXA1)+INAGL1)
dVA2/dT=-(IKA(VA2,KE2,KIA2)+INAA(VA2,NAE2,NAIA2)+IPUMPA(KE2,NAIA2,IMAXA2)+INAGL2)
dVA3/dT=-(IKA(VA3,KE3,KIA3)+INAA(VA3,NAE3,NAIA3)+IPUMPA(KE3,NAIA3,IMAXA3)+INAGL3)
dVA4/dT=-(IKA(VA4,KE4,KIA4)+INAA(VA4,NAE4,NAIA4)+IPUMPA(KE4,NAIA4,IMAXA4)+INAGL4)
dVA5/dT=-(IKA(VA5,KE5,KIA5)+INAA(VA5,NAE5,NAIA5)+IPUMPA(KE5,NAIA5,IMAXA5)+INAGL5)
dVA6/dT=-(IKA(VA6,KE6,KIA6)+INAA(VA6,NAE6,NAIA6)+IPUMPA(KE6,NAIA6,IMAXA6)+INAGL6)
dVA7/dT=-(IKA(VA7,KE7,KIA7)+INAA(VA7,NAE7,NAIA7)+IPUMPA(KE7,NAIA7,IMAXA7)+INAGL7)
dVA8/dT=-(IKA(VA8,KE8,KIA8)+INAA(VA8,NAE8,NAIA8)+IPUMPA(KE8,NAIA8,IMAXA8)+INAGL8)
dVA9/dT=-(IKA(VA9,KE9,KIA9)+INAA(VA9,NAE9,NAIA9)+IPUMPA(KE9,NAIA9,IMAXA9)+INAGL9)
dVA10/dT=-(IKA(VA10,KE10,KIA10)+INAA(VA10,NAE10,NAIA10)+IPUMPA(KE10,NAIA10,IMAXA10)+INAGL10)
dVA11/dT=-(IKA(VA11,KE11,KIA11)+INAA(VA11,NAE11,NAIA11)+IPUMPA(KE11,NAIA11,IMAXA11)+INAGL11)
dVA12/dT=-(IKA(VA12,KE12,KIA12)+INAA(VA12,NAE12,NAIA12)+IPUMPA(KE12,NAIA12,IMAXA12)+INAGL12)
dVA13/dT=-(IKA(VA13,KE13,KIA13)+INAA(VA13,NAE13,NAIA13)+IPUMPA(KE13,NAIA13,IMAXA13)+INAGL13)
dVA14/dT=-(IKA(VA14,KE14,KIA14)+INAA(VA14,NAE14,NAIA14)+IPUMPA(KE14,NAIA14,IMAXA14)+INAGL14)
dVA15/dT=-(IKA(VA15,KE15,KIA15)+INAA(VA15,NAE15,NAIA15)+IPUMPA(KE15,NAIA15,IMAXA15)+INAGL15)
dVA16/dT=-(IKA(VA16,KE16,KIA16)+INAA(VA16,NAE16,NAIA16)+IPUMPA(KE16,NAIA16,IMAXA16)+INAGL16)
dVA17/dT=-(IKA(VA17,KE17,KIA17)+INAA(VA17,NAE17,NAIA17)+IPUMPA(KE17,NAIA17,IMAXA17)+INAGL17)
dVA18/dT=-(IKA(VA18,KE18,KIA18)+INAA(VA18,NAE18,NAIA18)+IPUMPA(KE18,NAIA18,IMAXA18)+INAGL18)
dVA19/dT=-(IKA(VA19,KE19,KIA19)+INAA(VA19,NAE19,NAIA19)+IPUMPA(KE19,NAIA19,IMAXA19)+INAGL19)
dVA20/dT=-(IKA(VA20,KE20,KIA20)+INAA(VA20,NAE20,NAIA20)+IPUMPA(KE20,NAIA20,IMAXA20)+INAGL20)
dVA21/dT=-(IKA(VA21,KE21,KIA21)+INAA(VA21,NAE21,NAIA21)+IPUMPA(KE21,NAIA21,IMAXA21)+INAGL21)
dVA22/dT=-(IKA(VA22,KE22,KIA22)+INAA(VA22,NAE22,NAIA22)+IPUMPA(KE22,NAIA22,IMAXA22)+INAGL22)
dVA23/dT=-(IKA(VA23,KE23,KIA23)+INAA(VA23,NAE23,NAIA23)+IPUMPA(KE23,NAIA23,IMAXA23)+INAGL23)
dVA24/dT=-(IKA(VA24,KE24,KIA24)+INAA(VA24,NAE24,NAIA24)+IPUMPA(KE24,NAIA24,IMAXA24)+INAGL24)
dVA25/dT=-(IKA(VA25,KE25,KIA25)+INAA(VA25,NAE25,NAIA25)+IPUMPA(KE25,NAIA25,IMAXA25)+INAGL25)
dKE1/dT=C2*(IK(V1,N1,KE1,KI1)+IKPUMP1+IKNMDA1)+KDIFF1+C3E*(IKA(VA1,KE1,KIA1)-2*IPUMPA(KE1,NAIA1,IMAXA1)-INAGL1)+GKB*(K0-KE1)
dKE2/dT=C2*(IK(V2,N2,KE2,KI2)+IKPUMP2+IKNMDA2)+KDIFF2+C3E*(IKA(VA2,KE2,KIA2)-2*IPUMPA(KE2,NAIA2,IMAXA2)-INAGL2)+GKB*(K0-KE2)
dKE3/dT=C2*(IK(V3,N3,KE3,KI3)+IKPUMP3+IKNMDA3)+KDIFF3+C3E*(IKA(VA3,KE3,KIA3)-2*IPUMPA(KE3,NAIA3,IMAXA3)-INAGL3)+GKB*(K0-KE3)
dKE4/dT=C2*(IK(V4,N4,KE4,KI4)+IKPUMP4+IKNMDA4)+KDIFF4+C3E*(IKA(VA4,KE4,KIA4)-2*IPUMPA(KE4,NAIA4,IMAXA4)-INAGL4)+GKB*(K0-KE4)
dKE5/dT=C2*(IK(V5,N5,KE5,KI5)+IKPUMP5+IKNMDA5)+KDIFF5+C3E*(IKA(VA5,KE5,KIA5)-2*IPUMPA(KE5,NAIA5,IMAXA5)-INAGL5)+GKB*(K0-KE5)
dKE6/dT=C2*(IK(V6,N6,KE6,KI6)+IKPUMP6+IKNMDA6)+KDIFF6+C3E*(IKA(VA6,KE6,KIA6)-2*IPUMPA(KE6,NAIA6,IMAXA6)-INAGL6)+GKB*(K0-KE6)
dKE7/dT=C2*(IK(V7,N7,KE7,KI7)+IKPUMP7+IKNMDA7)+KDIFF7+C3E*(IKA(VA7,KE7,KIA7)-2*IPUMPA(KE7,NAIA7,IMAXA7)-INAGL7)+GKB*(K0-KE7)
dKE8/dT=C2*(IK(V8,N8,KE8,KI8)+IKPUMP8+IKNMDA8)+KDIFF8+C3E*(IKA(VA8,KE8,KIA8)-2*IPUMPA(KE8,NAIA8,IMAXA8)-INAGL8)+GKB*(K0-KE8)
dKE9/dT=C2*(IK(V9,N9,KE9,KI9)+IKPUMP9+IKNMDA9)+KDIFF9+C3E*(IKA(VA9,KE9,KIA9)-2*IPUMPA(KE9,NAIA9,IMAXA9)-INAGL9)+GKB*(K0-KE9)
dKE10/dT=C2*(IK(V10,N10,KE10,KI10)+IKPUMP10+IKNMDA10)+KDIFF10+C3E*(IKA(VA10,KE10,KIA10)-2*IPUMPA(KE10,NAIA10,IMAXA10)-INAGL10)+GKB*(K0-KE10)
dKE11/dT=C2*(IK(V11,N11,KE11,KI11)+IKPUMP11+IKNMDA11)+KDIFF11+C3E*(IKA(VA11,KE11,KIA11)-2*IPUMPA(KE11,NAIA11,IMAXA11)-INAGL11)+GKB*(K0-KE11)
dKE12/dT=C2*(IK(V12,N12,KE12,KI12)+IKPUMP12+IKNMDA12)+KDIFF12+C3E*(IKA(VA12,KE12,KIA12)-2*IPUMPA(KE12,NAIA12,IMAXA12)-INAGL12)+GKB*(K0-KE12)
dKE13/dT=C2*(IK(V13,N13,KE13,KI13)+IKPUMP13+IKNMDA13)+KDIFF13+C3E*(IKA(VA13,KE13,KIA13)-2*IPUMPA(KE13,NAIA13,IMAXA13)-INAGL13)+GKB*(K0-KE13)
dKE14/dT=C2*(IK(V14,N14,KE14,KI14)+IKPUMP14+IKNMDA14)+KDIFF14+C3E*(IKA(VA14,KE14,KIA14)-2*IPUMPA(KE14,NAIA14,IMAXA14)-INAGL14)+GKB*(K0-KE14)
dKE15/dT=C2*(IK(V15,N15,KE15,KI15)+IKPUMP15+IKNMDA15)+KDIFF15+C3E*(IKA(VA15,KE15,KIA15)-2*IPUMPA(KE15,NAIA15,IMAXA15)-INAGL15)+GKB*(K0-KE15)
dKE16/dT=C2*(IK(V16,N16,KE16,KI16)+IKPUMP16+IKNMDA16)+KDIFF16+C3E*(IKA(VA16,KE16,KIA16)-2*IPUMPA(KE16,NAIA16,IMAXA16)-INAGL16)+GKB*(K0-KE16)
dKE17/dT=C2*(IK(V17,N17,KE17,KI17)+IKPUMP17+IKNMDA17)+KDIFF17+C3E*(IKA(VA17,KE17,KIA17)-2*IPUMPA(KE17,NAIA17,IMAXA17)-INAGL17)+GKB*(K0-KE17)
dKE18/dT=C2*(IK(V18,N18,KE18,KI18)+IKPUMP18+IKNMDA18)+KDIFF18+C3E*(IKA(VA18,KE18,KIA18)-2*IPUMPA(KE18,NAIA18,IMAXA18)-INAGL18)+GKB*(K0-KE18)
dKE19/dT=C2*(IK(V19,N19,KE19,KI19)+IKPUMP19+IKNMDA19)+KDIFF19+C3E*(IKA(VA19,KE19,KIA19)-2*IPUMPA(KE19,NAIA19,IMAXA19)-INAGL19)+GKB*(K0-KE19)
dKE20/dT=C2*(IK(V20,N20,KE20,KI20)+IKPUMP20+IKNMDA20)+KDIFF20+C3E*(IKA(VA20,KE20,KIA20)-2*IPUMPA(KE20,NAIA20,IMAXA20)-INAGL20)+GKB*(K0-KE20)
dKE21/dT=C2*(IK(V21,N21,KE21,KI21)+IKPUMP21+IKNMDA21)+KDIFF21+C3E*(IKA(VA21,KE21,KIA21)-2*IPUMPA(KE21,NAIA21,IMAXA21)-INAGL21)+GKB*(K0-KE21)
dKE22/dT=C2*(IK(V22,N22,KE22,KI22)+IKPUMP22+IKNMDA22)+KDIFF22+C3E*(IKA(VA22,KE22,KIA22)-2*IPUMPA(KE22,NAIA22,IMAXA22)-INAGL22)+GKB*(K0-KE22)
dKE23/dT=C2*(IK(V23,N23,KE23,KI23)+IKPUMP23+IKNMDA23)+KDIFF23+C3E*(IKA(VA23,KE23,KIA23)-2*IPUMPA(KE23,NAIA23,IMAXA23)-INAGL23)+GKB*(K0-KE23)
dKE24/dT=C2*(IK(V24,N24,KE24,KI24)+IKPUMP24+IKNMDA24)+KDIFF24+C3E*(IKA(VA24,KE24,KIA24)-2*IPUMPA(KE24,NAIA24,IMAXA24)-INAGL24)+GKB*(K0-KE24)
dKE25/dT=C2*(IK(V25,N25,KE25,KI25)+IKPUMP25+IKNMDA25)+KDIFF25+C3E*(IKA(VA25,KE25,KIA25)-2*IPUMPA(KE25,NAIA25,IMAXA25)-INAGL25)+GKB*(K0-KE25)
dNAI1/dT=-C1*(INA(V1,N1,NAE1,NAI1)+INAP(V1,HP1,NAE1,NAI1)+INAPUMP1+INANMDA1)
dNAI2/dT=-C1*(INA(V2,N2,NAE2,NAI2)+INAP(V2,HP2,NAE2,NAI2)+INAPUMP2+INANMDA2)
dNAI3/dT=-C1*(INA(V3,N3,NAE3,NAI3)+INAP(V3,HP3,NAE3,NAI3)+INAPUMP3+INANMDA3)
dNAI4/dT=-C1*(INA(V4,N4,NAE4,NAI4)+INAP(V4,HP4,NAE4,NAI4)+INAPUMP4+INANMDA4)
dNAI5/dT=-C1*(INA(V5,N5,NAE5,NAI5)+INAP(V5,HP5,NAE5,NAI5)+INAPUMP5+INANMDA5)
dNAI6/dT=-C1*(INA(V6,N6,NAE6,NAI6)+INAP(V6,HP6,NAE6,NAI6)+INAPUMP6+INANMDA6)
dNAI7/dT=-C1*(INA(V7,N7,NAE7,NAI7)+INAP(V7,HP7,NAE7,NAI7)+INAPUMP7+INANMDA7)
dNAI8/dT=-C1*(INA(V8,N8,NAE8,NAI8)+INAP(V8,HP8,NAE8,NAI8)+INAPUMP8+INANMDA8)
dNAI9/dT=-C1*(INA(V9,N9,NAE9,NAI9)+INAP(V9,HP9,NAE9,NAI9)+INAPUMP9+INANMDA9)
dNAI10/dT=-C1*(INA(V10,N10,NAE10,NAI10)+INAP(V10,HP10,NAE10,NAI10)+INAPUMP10+INANMDA10)
dNAI11/dT=-C1*(INA(V11,N11,NAE11,NAI11)+INAP(V11,HP11,NAE11,NAI11)+INAPUMP11+INANMDA11)
dNAI12/dT=-C1*(INA(V12,N12,NAE12,NAI12)+INAP(V12,HP12,NAE12,NAI12)+INAPUMP12+INANMDA12)
dNAI13/dT=-C1*(INA(V13,N13,NAE13,NAI13)+INAP(V13,HP13,NAE13,NAI13)+INAPUMP13+INANMDA13)
dNAI14/dT=-C1*(INA(V14,N14,NAE14,NAI14)+INAP(V14,HP14,NAE14,NAI14)+INAPUMP14+INANMDA14)
dNAI15/dT=-C1*(INA(V15,N15,NAE15,NAI15)+INAP(V15,HP15,NAE15,NAI15)+INAPUMP15+INANMDA15)
dNAI16/dT=-C1*(INA(V16,N16,NAE16,NAI16)+INAP(V16,HP16,NAE16,NAI16)+INAPUMP16+INANMDA16)
dNAI17/dT=-C1*(INA(V17,N17,NAE17,NAI17)+INAP(V17,HP17,NAE17,NAI17)+INAPUMP17+INANMDA17)
dNAI18/dT=-C1*(INA(V18,N18,NAE18,NAI18)+INAP(V18,HP18,NAE18,NAI18)+INAPUMP18+INANMDA18)
dNAI19/dT=-C1*(INA(V19,N19,NAE19,NAI19)+INAP(V19,HP19,NAE19,NAI19)+INAPUMP19+INANMDA19)
dNAI20/dT=-C1*(INA(V20,N20,NAE20,NAI20)+INAP(V20,HP20,NAE20,NAI20)+INAPUMP20+INANMDA20)
dNAI21/dT=-C1*(INA(V21,N21,NAE21,NAI21)+INAP(V21,HP21,NAE21,NAI21)+INAPUMP21+INANMDA21)
dNAI22/dT=-C1*(INA(V22,N22,NAE22,NAI22)+INAP(V22,HP22,NAE22,NAI22)+INAPUMP22+INANMDA22)
dNAI23/dT=-C1*(INA(V23,N23,NAE23,NAI23)+INAP(V23,HP23,NAE23,NAI23)+INAPUMP23+INANMDA23)
dNAI24/dT=-C1*(INA(V24,N24,NAE24,NAI24)+INAP(V24,HP24,NAE24,NAI24)+INAPUMP24+INANMDA24)
dNAI25/dT=-C1*(INA(V25,N25,NAE25,NAI25)+INAP(V25,HP25,NAE25,NAI25)+INAPUMP25+INANMDA25)
dNAE1/dT=C2*(INA(V1,N1,NAE1,NAI1)+INAP(V1,HP1,NAE1,NAI1)+INAPUMP1+INANMDA1)+NADIFF1+C3E*(INAA(VA1,NAE1,NAIA1)+3*IPUMPA(KE1,NAIA1,IMAXA1)+(3)*INAGL1)+GNAB*(NA0-NAE1)
dNAE2/dT=C2*(INA(V2,N2,NAE2,NAI2)+INAP(V2,HP2,NAE2,NAI2)+INAPUMP2+INANMDA2)+NADIFF2+C3E*(INAA(VA2,NAE2,NAIA2)+3*IPUMPA(KE2,NAIA2,IMAXA2)+(3)*INAGL2)+GNAB*(NA0-NAE2)
dNAE3/dT=C2*(INA(V3,N3,NAE3,NAI3)+INAP(V3,HP3,NAE3,NAI3)+INAPUMP3+INANMDA3)+NADIFF3+C3E*(INAA(VA3,NAE3,NAIA3)+3*IPUMPA(KE3,NAIA3,IMAXA3)+(3)*INAGL3)+GNAB*(NA0-NAE3)
dNAE4/dT=C2*(INA(V4,N4,NAE4,NAI4)+INAP(V4,HP4,NAE4,NAI4)+INAPUMP4+INANMDA4)+NADIFF4+C3E*(INAA(VA4,NAE4,NAIA4)+3*IPUMPA(KE4,NAIA4,IMAXA4)+(3)*INAGL4)+GNAB*(NA0-NAE4)
dNAE5/dT=C2*(INA(V5,N5,NAE5,NAI5)+INAP(V5,HP5,NAE5,NAI5)+INAPUMP5+INANMDA5)+NADIFF5+C3E*(INAA(VA5,NAE5,NAIA5)+3*IPUMPA(KE5,NAIA5,IMAXA5)+(3)*INAGL5)+GNAB*(NA0-NAE5)
dNAE6/dT=C2*(INA(V6,N6,NAE6,NAI6)+INAP(V6,HP6,NAE6,NAI6)+INAPUMP6+INANMDA6)+NADIFF6+C3E*(INAA(VA6,NAE6,NAIA6)+3*IPUMPA(KE6,NAIA6,IMAXA6)+(3)*INAGL6)+GNAB*(NA0-NAE6)
dNAE7/dT=C2*(INA(V7,N7,NAE7,NAI7)+INAP(V7,HP7,NAE7,NAI7)+INAPUMP7+INANMDA7)+NADIFF7+C3E*(INAA(VA7,NAE7,NAIA7)+3*IPUMPA(KE7,NAIA7,IMAXA7)+(3)*INAGL7)+GNAB*(NA0-NAE7)
dNAE8/dT=C2*(INA(V8,N8,NAE8,NAI8)+INAP(V8,HP8,NAE8,NAI8)+INAPUMP8+INANMDA8)+NADIFF8+C3E*(INAA(VA8,NAE8,NAIA8)+3*IPUMPA(KE8,NAIA8,IMAXA8)+(3)*INAGL8)+GNAB*(NA0-NAE8)
dNAE9/dT=C2*(INA(V9,N9,NAE9,NAI9)+INAP(V9,HP9,NAE9,NAI9)+INAPUMP9+INANMDA9)+NADIFF9+C3E*(INAA(VA9,NAE9,NAIA9)+3*IPUMPA(KE9,NAIA9,IMAXA9)+(3)*INAGL9)+GNAB*(NA0-NAE9)
dNAE10/dT=C2*(INA(V10,N10,NAE10,NAI10)+INAP(V10,HP10,NAE10,NAI10)+INAPUMP10+INANMDA10)+NADIFF10+C3E*(INAA(VA10,NAE10,NAIA10)+3*IPUMPA(KE10,NAIA10,IMAXA10)+(3)*INAGL10)+GNAB*(NA0-NAE10)
dNAE11/dT=C2*(INA(V11,N11,NAE11,NAI11)+INAP(V11,HP11,NAE11,NAI11)+INAPUMP11+INANMDA11)+NADIFF11+C3E*(INAA(VA11,NAE11,NAIA11)+3*IPUMPA(KE11,NAIA11,IMAXA11)+(3)*INAGL11)+GNAB*(NA0-NAE11)
dNAE12/dT=C2*(INA(V12,N12,NAE12,NAI12)+INAP(V12,HP12,NAE12,NAI12)+INAPUMP12+INANMDA12)+NADIFF12+C3E*(INAA(VA12,NAE12,NAIA12)+3*IPUMPA(KE12,NAIA12,IMAXA12)+(3)*INAGL12)+GNAB*(NA0-NAE12)
dNAE13/dT=C2*(INA(V13,N13,NAE13,NAI13)+INAP(V13,HP13,NAE13,NAI13)+INAPUMP13+INANMDA13)+NADIFF13+C3E*(INAA(VA13,NAE13,NAIA13)+3*IPUMPA(KE13,NAIA13,IMAXA13)+(3)*INAGL13)+GNAB*(NA0-NAE13)
dNAE14/dT=C2*(INA(V14,N14,NAE14,NAI14)+INAP(V14,HP14,NAE14,NAI14)+INAPUMP14+INANMDA14)+NADIFF14+C3E*(INAA(VA14,NAE14,NAIA14)+3*IPUMPA(KE14,NAIA14,IMAXA14)+(3)*INAGL14)+GNAB*(NA0-NAE14)
dNAE15/dT=C2*(INA(V15,N15,NAE15,NAI15)+INAP(V15,HP15,NAE15,NAI15)+INAPUMP15+INANMDA15)+NADIFF15+C3E*(INAA(VA15,NAE15,NAIA15)+3*IPUMPA(KE15,NAIA15,IMAXA15)+(3)*INAGL15)+GNAB*(NA0-NAE15)
dNAE16/dT=C2*(INA(V16,N16,NAE16,NAI16)+INAP(V16,HP16,NAE16,NAI16)+INAPUMP16+INANMDA16)+NADIFF16+C3E*(INAA(VA16,NAE16,NAIA16)+3*IPUMPA(KE16,NAIA16,IMAXA16)+(3)*INAGL16)+GNAB*(NA0-NAE16)
dNAE17/dT=C2*(INA(V17,N17,NAE17,NAI17)+INAP(V17,HP17,NAE17,NAI17)+INAPUMP17+INANMDA17)+NADIFF17+C3E*(INAA(VA17,NAE17,NAIA17)+3*IPUMPA(KE17,NAIA17,IMAXA17)+(3)*INAGL17)+GNAB*(NA0-NAE17)
dNAE18/dT=C2*(INA(V18,N18,NAE18,NAI18)+INAP(V18,HP18,NAE18,NAI18)+INAPUMP18+INANMDA18)+NADIFF18+C3E*(INAA(VA18,NAE18,NAIA18)+3*IPUMPA(KE18,NAIA18,IMAXA18)+(3)*INAGL18)+GNAB*(NA0-NAE18)
dNAE19/dT=C2*(INA(V19,N19,NAE19,NAI19)+INAP(V19,HP19,NAE19,NAI19)+INAPUMP19+INANMDA19)+NADIFF19+C3E*(INAA(VA19,NAE19,NAIA19)+3*IPUMPA(KE19,NAIA19,IMAXA19)+(3)*INAGL19)+GNAB*(NA0-NAE19)
dNAE20/dT=C2*(INA(V20,N20,NAE20,NAI20)+INAP(V20,HP20,NAE20,NAI20)+INAPUMP20+INANMDA20)+NADIFF20+C3E*(INAA(VA20,NAE20,NAIA20)+3*IPUMPA(KE20,NAIA20,IMAXA20)+(3)*INAGL20)+GNAB*(NA0-NAE20)
dNAE21/dT=C2*(INA(V21,N21,NAE21,NAI21)+INAP(V21,HP21,NAE21,NAI21)+INAPUMP21+INANMDA21)+NADIFF21+C3E*(INAA(VA21,NAE21,NAIA21)+3*IPUMPA(KE21,NAIA21,IMAXA21)+(3)*INAGL21)+GNAB*(NA0-NAE21)
dNAE22/dT=C2*(INA(V22,N22,NAE22,NAI22)+INAP(V22,HP22,NAE22,NAI22)+INAPUMP22+INANMDA22)+NADIFF22+C3E*(INAA(VA22,NAE22,NAIA22)+3*IPUMPA(KE22,NAIA22,IMAXA22)+(3)*INAGL22)+GNAB*(NA0-NAE22)
dNAE23/dT=C2*(INA(V23,N23,NAE23,NAI23)+INAP(V23,HP23,NAE23,NAI23)+INAPUMP23+INANMDA23)+NADIFF23+C3E*(INAA(VA23,NAE23,NAIA23)+3*IPUMPA(KE23,NAIA23,IMAXA23)+(3)*INAGL23)+GNAB*(NA0-NAE23)
dNAE24/dT=C2*(INA(V24,N24,NAE24,NAI24)+INAP(V24,HP24,NAE24,NAI24)+INAPUMP24+INANMDA24)+NADIFF24+C3E*(INAA(VA24,NAE24,NAIA24)+3*IPUMPA(KE24,NAIA24,IMAXA24)+(3)*INAGL24)+GNAB*(NA0-NAE24)
dNAE25/dT=C2*(INA(V25,N25,NAE25,NAI25)+INAP(V25,HP25,NAE25,NAI25)+INAPUMP25+INANMDA25)+NADIFF25+C3E*(INAA(VA25,NAE25,NAIA25)+3*IPUMPA(KE25,NAIA25,IMAXA25)+(3)*INAGL25)+GNAB*(NA0-NAE25)
dKI1/dT=-C1*(IK(V1,N1,KE1,KI1)+IKPUMP1+IKNMDA1)
dKI2/dT=-C1*(IK(V2,N2,KE2,KI2)+IKPUMP2+IKNMDA2)
dKI3/dT=-C1*(IK(V3,N3,KE3,KI3)+IKPUMP3+IKNMDA3)
dKI4/dT=-C1*(IK(V4,N4,KE4,KI4)+IKPUMP4+IKNMDA4)
dKI5/dT=-C1*(IK(V5,N5,KE5,KI5)+IKPUMP5+IKNMDA5)
dKI6/dT=-C1*(IK(V6,N6,KE6,KI6)+IKPUMP6+IKNMDA6)
dKI7/dT=-C1*(IK(V7,N7,KE7,KI7)+IKPUMP7+IKNMDA7)
dKI8/dT=-C1*(IK(V8,N8,KE8,KI8)+IKPUMP8+IKNMDA8)
dKI9/dT=-C1*(IK(V9,N9,KE9,KI9)+IKPUMP9+IKNMDA9)
dKI10/dT=-C1*(IK(V10,N10,KE10,KI10)+IKPUMP10+IKNMDA10)
dKI11/dT=-C1*(IK(V11,N11,KE11,KI11)+IKPUMP11+IKNMDA11)
dKI12/dT=-C1*(IK(V12,N12,KE12,KI12)+IKPUMP12+IKNMDA12)
dKI13/dT=-C1*(IK(V13,N13,KE13,KI13)+IKPUMP13+IKNMDA13)
dKI14/dT=-C1*(IK(V14,N14,KE14,KI14)+IKPUMP14+IKNMDA14)
dKI15/dT=-C1*(IK(V15,N15,KE15,KI15)+IKPUMP15+IKNMDA15)
dKI16/dT=-C1*(IK(V16,N16,KE16,KI16)+IKPUMP16+IKNMDA16)
dKI17/dT=-C1*(IK(V17,N17,KE17,KI17)+IKPUMP17+IKNMDA17)
dKI18/dT=-C1*(IK(V18,N18,KE18,KI18)+IKPUMP18+IKNMDA18)
dKI19/dT=-C1*(IK(V19,N19,KE19,KI19)+IKPUMP19+IKNMDA19)
dKI20/dT=-C1*(IK(V20,N20,KE20,KI20)+IKPUMP20+IKNMDA20)
dKI21/dT=-C1*(IK(V21,N21,KE21,KI21)+IKPUMP21+IKNMDA21)
dKI22/dT=-C1*(IK(V22,N22,KE22,KI22)+IKPUMP22+IKNMDA22)
dKI23/dT=-C1*(IK(V23,N23,KE23,KI23)+IKPUMP23+IKNMDA23)
dKI24/dT=-C1*(IK(V24,N24,KE24,KI24)+IKPUMP24+IKNMDA24)
dKI25/dT=-C1*(IK(V25,N25,KE25,KI25)+IKPUMP25+IKNMDA25)
dKIA1/dT=-C3A*(IKA(VA1,KE1,KIA1)-2*IPUMPA(KE1,NAIA1,IMAXA1)-INAGL1)
dKIA2/dT=-C3A*(IKA(VA2,KE2,KIA2)-2*IPUMPA(KE2,NAIA2,IMAXA2)-INAGL2)
dKIA3/dT=-C3A*(IKA(VA3,KE3,KIA3)-2*IPUMPA(KE3,NAIA3,IMAXA3)-INAGL3)
dKIA4/dT=-C3A*(IKA(VA4,KE4,KIA4)-2*IPUMPA(KE4,NAIA4,IMAXA4)-INAGL4)
dKIA5/dT=-C3A*(IKA(VA5,KE5,KIA5)-2*IPUMPA(KE5,NAIA5,IMAXA5)-INAGL5)
dKIA6/dT=-C3A*(IKA(VA6,KE6,KIA6)-2*IPUMPA(KE6,NAIA6,IMAXA6)-INAGL6)
dKIA7/dT=-C3A*(IKA(VA7,KE7,KIA7)-2*IPUMPA(KE7,NAIA7,IMAXA7)-INAGL7)
dKIA8/dT=-C3A*(IKA(VA8,KE8,KIA8)-2*IPUMPA(KE8,NAIA8,IMAXA8)-INAGL8)
dKIA9/dT=-C3A*(IKA(VA9,KE9,KIA9)-2*IPUMPA(KE9,NAIA9,IMAXA9)-INAGL9)
dKIA10/dT=-C3A*(IKA(VA10,KE10,KIA10)-2*IPUMPA(KE10,NAIA10,IMAXA10)-INAGL10)
dKIA11/dT=-C3A*(IKA(VA11,KE11,KIA11)-2*IPUMPA(KE11,NAIA11,IMAXA11)-INAGL11)
dKIA12/dT=-C3A*(IKA(VA12,KE12,KIA12)-2*IPUMPA(KE12,NAIA12,IMAXA12)-INAGL12)
dKIA13/dT=-C3A*(IKA(VA13,KE13,KIA13)-2*IPUMPA(KE13,NAIA13,IMAXA13)-INAGL13)
dKIA14/dT=-C3A*(IKA(VA14,KE14,KIA14)-2*IPUMPA(KE14,NAIA14,IMAXA14)-INAGL14)
dKIA15/dT=-C3A*(IKA(VA15,KE15,KIA15)-2*IPUMPA(KE15,NAIA15,IMAXA15)-INAGL15)
dKIA16/dT=-C3A*(IKA(VA16,KE16,KIA16)-2*IPUMPA(KE16,NAIA16,IMAXA16)-INAGL16)
dKIA17/dT=-C3A*(IKA(VA17,KE17,KIA17)-2*IPUMPA(KE17,NAIA17,IMAXA17)-INAGL17)
dKIA18/dT=-C3A*(IKA(VA18,KE18,KIA18)-2*IPUMPA(KE18,NAIA18,IMAXA18)-INAGL18)
dKIA19/dT=-C3A*(IKA(VA19,KE19,KIA19)-2*IPUMPA(KE19,NAIA19,IMAXA19)-INAGL19)
dKIA20/dT=-C3A*(IKA(VA20,KE20,KIA20)-2*IPUMPA(KE20,NAIA20,IMAXA20)-INAGL20)
dKIA21/dT=-C3A*(IKA(VA21,KE21,KIA21)-2*IPUMPA(KE21,NAIA21,IMAXA21)-INAGL21)
dKIA22/dT=-C3A*(IKA(VA22,KE22,KIA22)-2*IPUMPA(KE22,NAIA22,IMAXA22)-INAGL22)
dKIA23/dT=-C3A*(IKA(VA23,KE23,KIA23)-2*IPUMPA(KE23,NAIA23,IMAXA23)-INAGL23)
dKIA24/dT=-C3A*(IKA(VA24,KE24,KIA24)-2*IPUMPA(KE24,NAIA24,IMAXA24)-INAGL24)
dKIA25/dT=-C3A*(IKA(VA25,KE25,KIA25)-2*IPUMPA(KE25,NAIA25,IMAXA25)-INAGL25)
dNAIA1/dT=-C3A*(INAA(VA1,NAE1,NAIA1)+3*IPUMPA(KE1,NAIA1,IMAXA1)+(3)*INAGL1)
dNAIA2/dT=-C3A*(INAA(VA2,NAE2,NAIA2)+3*IPUMPA(KE2,NAIA2,IMAXA2)+(3)*INAGL2)
dNAIA3/dT=-C3A*(INAA(VA3,NAE3,NAIA3)+3*IPUMPA(KE3,NAIA3,IMAXA3)+(3)*INAGL3)
dNAIA4/dT=-C3A*(INAA(VA4,NAE4,NAIA4)+3*IPUMPA(KE4,NAIA4,IMAXA4)+(3)*INAGL4)
dNAIA5/dT=-C3A*(INAA(VA5,NAE5,NAIA5)+3*IPUMPA(KE5,NAIA5,IMAXA5)+(3)*INAGL5)
dNAIA6/dT=-C3A*(INAA(VA6,NAE6,NAIA6)+3*IPUMPA(KE6,NAIA6,IMAXA6)+(3)*INAGL6)
dNAIA7/dT=-C3A*(INAA(VA7,NAE7,NAIA7)+3*IPUMPA(KE7,NAIA7,IMAXA7)+(3)*INAGL7)
dNAIA8/dT=-C3A*(INAA(VA8,NAE8,NAIA8)+3*IPUMPA(KE8,NAIA8,IMAXA8)+(3)*INAGL8)
dNAIA9/dT=-C3A*(INAA(VA9,NAE9,NAIA9)+3*IPUMPA(KE9,NAIA9,IMAXA9)+(3)*INAGL9)
dNAIA10/dT=-C3A*(INAA(VA10,NAE10,NAIA10)+3*IPUMPA(KE10,NAIA10,IMAXA10)+(3)*INAGL10)
dNAIA11/dT=-C3A*(INAA(VA11,NAE11,NAIA11)+3*IPUMPA(KE11,NAIA11,IMAXA11)+(3)*INAGL11)
dNAIA12/dT=-C3A*(INAA(VA12,NAE12,NAIA12)+3*IPUMPA(KE12,NAIA12,IMAXA12)+(3)*INAGL12)
dNAIA13/dT=-C3A*(INAA(VA13,NAE13,NAIA13)+3*IPUMPA(KE13,NAIA13,IMAXA13)+(3)*INAGL13)
dNAIA14/dT=-C3A*(INAA(VA14,NAE14,NAIA14)+3*IPUMPA(KE14,NAIA14,IMAXA14)+(3)*INAGL14)
dNAIA15/dT=-C3A*(INAA(VA15,NAE15,NAIA15)+3*IPUMPA(KE15,NAIA15,IMAXA15)+(3)*INAGL15)
dNAIA16/dT=-C3A*(INAA(VA16,NAE16,NAIA16)+3*IPUMPA(KE16,NAIA16,IMAXA16)+(3)*INAGL16)
dNAIA17/dT=-C3A*(INAA(VA17,NAE17,NAIA17)+3*IPUMPA(KE17,NAIA17,IMAXA17)+(3)*INAGL17)
dNAIA18/dT=-C3A*(INAA(VA18,NAE18,NAIA18)+3*IPUMPA(KE18,NAIA18,IMAXA18)+(3)*INAGL18)
dNAIA19/dT=-C3A*(INAA(VA19,NAE19,NAIA19)+3*IPUMPA(KE19,NAIA19,IMAXA19)+(3)*INAGL19)
dNAIA20/dT=-C3A*(INAA(VA20,NAE20,NAIA20)+3*IPUMPA(KE20,NAIA20,IMAXA20)+(3)*INAGL20)
dNAIA21/dT=-C3A*(INAA(VA21,NAE21,NAIA21)+3*IPUMPA(KE21,NAIA21,IMAXA21)+(3)*INAGL21)
dNAIA22/dT=-C3A*(INAA(VA22,NAE22,NAIA22)+3*IPUMPA(KE22,NAIA22,IMAXA22)+(3)*INAGL22)
dNAIA23/dT=-C3A*(INAA(VA23,NAE23,NAIA23)+3*IPUMPA(KE23,NAIA23,IMAXA23)+(3)*INAGL23)
dNAIA24/dT=-C3A*(INAA(VA24,NAE24,NAIA24)+3*IPUMPA(KE24,NAIA24,IMAXA24)+(3)*INAGL24)
dNAIA25/dT=-C3A*(INAA(VA25,NAE25,NAIA25)+3*IPUMPA(KE25,NAIA25,IMAXA25)+(3)*INAGL25)
dCLE1/dT=-C2*ICL1+GCLB*(CL0-CLE1)
dCLE2/dT=-C2*ICL2+GCLB*(CL0-CLE2)
dCLE3/dT=-C2*ICL3+GCLB*(CL0-CLE3)
dCLE4/dT=-C2*ICL4+GCLB*(CL0-CLE4)
dCLE5/dT=-C2*ICL5+GCLB*(CL0-CLE5)
dCLE6/dT=-C2*ICL6+GCLB*(CL0-CLE6)
dCLE7/dT=-C2*ICL7+GCLB*(CL0-CLE7)
dCLE8/dT=-C2*ICL8+GCLB*(CL0-CLE8)
dCLE9/dT=-C2*ICL9+GCLB*(CL0-CLE9)
dCLE10/dT=-C2*ICL10+GCLB*(CL0-CLE10)
dCLE11/dT=-C2*ICL11+GCLB*(CL0-CLE11)
dCLE12/dT=-C2*ICL12+GCLB*(CL0-CLE12)
dCLE13/dT=-C2*ICL13+GCLB*(CL0-CLE13)
dCLE14/dT=-C2*ICL14+GCLB*(CL0-CLE14)
dCLE15/dT=-C2*ICL15+GCLB*(CL0-CLE15)
dCLE16/dT=-C2*ICL16+GCLB*(CL0-CLE16)
dCLE17/dT=-C2*ICL17+GCLB*(CL0-CLE17)
dCLE18/dT=-C2*ICL18+GCLB*(CL0-CLE18)
dCLE19/dT=-C2*ICL19+GCLB*(CL0-CLE19)
dCLE20/dT=-C2*ICL20+GCLB*(CL0-CLE20)
dCLE21/dT=-C2*ICL21+GCLB*(CL0-CLE21)
dCLE22/dT=-C2*ICL22+GCLB*(CL0-CLE22)
dCLE23/dT=-C2*ICL23+GCLB*(CL0-CLE23)
dCLE24/dT=-C2*ICL24+GCLB*(CL0-CLE24)
dCLE25/dT=-C2*ICL25+GCLB*(CL0-CLE25)
dCLI1/dT=C1*ICL1
dCLI2/dT=C1*ICL2
dCLI3/dT=C1*ICL3
dCLI4/dT=C1*ICL4
dCLI5/dT=C1*ICL5
dCLI6/dT=C1*ICL6
dCLI7/dT=C1*ICL7
dCLI8/dT=C1*ICL8
dCLI9/dT=C1*ICL9
dCLI10/dT=C1*ICL10
dCLI11/dT=C1*ICL11
dCLI12/dT=C1*ICL12
dCLI13/dT=C1*ICL13
dCLI14/dT=C1*ICL14
dCLI15/dT=C1*ICL15
dCLI16/dT=C1*ICL16
dCLI17/dT=C1*ICL17
dCLI18/dT=C1*ICL18
dCLI19/dT=C1*ICL19
dCLI20/dT=C1*ICL20
dCLI21/dT=C1*ICL21
dCLI22/dT=C1*ICL22
dCLI23/dT=C1*ICL23
dCLI24/dT=C1*ICL24
dCLI25/dT=C1*ICL25
dGLUT1/dT=C3E*INAGL1+GDIFF1
dGLUT2/dT=C3E*INAGL2+GDIFF2
dGLUT3/dT=C3E*INAGL3+GDIFF3
dGLUT4/dT=C3E*INAGL4+GDIFF4
dGLUT5/dT=C3E*INAGL5+GDIFF5
dGLUT6/dT=C3E*INAGL6+GDIFF6
dGLUT7/dT=C3E*INAGL7+GDIFF7
dGLUT8/dT=C3E*INAGL8+GDIFF8
dGLUT9/dT=C3E*INAGL9+GDIFF9
dGLUT10/dT=C3E*INAGL10+GDIFF10
dGLUT11/dT=C3E*INAGL11+GDIFF11
dGLUT12/dT=C3E*INAGL12+GDIFF12
dGLUT13/dT=C3E*INAGL13+GDIFF13
dGLUT14/dT=C3E*INAGL14+GDIFF14
dGLUT15/dT=C3E*INAGL15+GDIFF15
dGLUT16/dT=C3E*INAGL16+GDIFF16
dGLUT17/dT=C3E*INAGL17+GDIFF17
dGLUT18/dT=C3E*INAGL18+GDIFF18
dGLUT19/dT=C3E*INAGL19+GDIFF19
dGLUT20/dT=C3E*INAGL20+GDIFF20
dGLUT21/dT=C3E*INAGL21+GDIFF21
dGLUT22/dT=C3E*INAGL22+GDIFF22
dGLUT23/dT=C3E*INAGL23+GDIFF23
dGLUT24/dT=C3E*INAGL24+GDIFF24
dGLUT25/dT=C3E*INAGL25+GDIFF25
dCAE1/dT=C2*(ICANMDA1)+GCAB*(CAE0-CAE1)
dCAE2/dT=C2*(ICANMDA2)+GCAB*(CAE0-CAE2)
dCAE3/dT=C2*(ICANMDA3)+GCAB*(CAE0-CAE3)
dCAE4/dT=C2*(ICANMDA4)+GCAB*(CAE0-CAE4)
dCAE5/dT=C2*(ICANMDA5)+GCAB*(CAE0-CAE5)
dCAE6/dT=C2*(ICANMDA6)+GCAB*(CAE0-CAE6)
dCAE7/dT=C2*(ICANMDA7)+GCAB*(CAE0-CAE7)
dCAE8/dT=C2*(ICANMDA8)+GCAB*(CAE0-CAE8)
dCAE9/dT=C2*(ICANMDA9)+GCAB*(CAE0-CAE9)
dCAE10/dT=C2*(ICANMDA10)+GCAB*(CAE0-CAE10)
dCAE11/dT=C2*(ICANMDA11)+GCAB*(CAE0-CAE11)
dCAE12/dT=C2*(ICANMDA12)+GCAB*(CAE0-CAE12)
dCAE13/dT=C2*(ICANMDA13)+GCAB*(CAE0-CAE13)
dCAE14/dT=C2*(ICANMDA14)+GCAB*(CAE0-CAE14)
dCAE15/dT=C2*(ICANMDA15)+GCAB*(CAE0-CAE15)
dCAE16/dT=C2*(ICANMDA16)+GCAB*(CAE0-CAE16)
dCAE17/dT=C2*(ICANMDA17)+GCAB*(CAE0-CAE17)
dCAE18/dT=C2*(ICANMDA18)+GCAB*(CAE0-CAE18)
dCAE19/dT=C2*(ICANMDA19)+GCAB*(CAE0-CAE19)
dCAE20/dT=C2*(ICANMDA20)+GCAB*(CAE0-CAE20)
dCAE21/dT=C2*(ICANMDA21)+GCAB*(CAE0-CAE21)
dCAE22/dT=C2*(ICANMDA22)+GCAB*(CAE0-CAE22)
dCAE23/dT=C2*(ICANMDA23)+GCAB*(CAE0-CAE23)
dCAE24/dT=C2*(ICANMDA24)+GCAB*(CAE0-CAE24)
dCAE25/dT=C2*(ICANMDA25)+GCAB*(CAE0-CAE25)
dCAI1/dT=-FI*C1*(ICANMDA1)-FI*(E*(JSERCA1-JEROUT1))/(VC*MINUTE*SECOND)
dCAI2/dT=-FI*C1*(ICANMDA2)-FI*(E*(JSERCA2-JEROUT2))/(VC*MINUTE*SECOND)
dCAI3/dT=-FI*C1*(ICANMDA3)-FI*(E*(JSERCA3-JEROUT3))/(VC*MINUTE*SECOND)
dCAI4/dT=-FI*C1*(ICANMDA4)-FI*(E*(JSERCA4-JEROUT4))/(VC*MINUTE*SECOND)
dCAI5/dT=-FI*C1*(ICANMDA5)-FI*(E*(JSERCA5-JEROUT5))/(VC*MINUTE*SECOND)
dCAI6/dT=-FI*C1*(ICANMDA6)-FI*(E*(JSERCA6-JEROUT6))/(VC*MINUTE*SECOND)
dCAI7/dT=-FI*C1*(ICANMDA7)-FI*(E*(JSERCA7-JEROUT7))/(VC*MINUTE*SECOND)
dCAI8/dT=-FI*C1*(ICANMDA8)-FI*(E*(JSERCA8-JEROUT8))/(VC*MINUTE*SECOND)
dCAI9/dT=-FI*C1*(ICANMDA9)-FI*(E*(JSERCA9-JEROUT9))/(VC*MINUTE*SECOND)
dCAI10/dT=-FI*C1*(ICANMDA10)-FI*(E*(JSERCA10-JEROUT10))/(VC*MINUTE*SECOND)
dCAI11/dT=-FI*C1*(ICANMDA11)-FI*(E*(JSERCA11-JEROUT11))/(VC*MINUTE*SECOND)
dCAI12/dT=-FI*C1*(ICANMDA12)-FI*(E*(JSERCA12-JEROUT12))/(VC*MINUTE*SECOND)
dCAI13/dT=-FI*C1*(ICANMDA13)-FI*(E*(JSERCA13-JEROUT13))/(VC*MINUTE*SECOND)
dCAI14/dT=-FI*C1*(ICANMDA14)-FI*(E*(JSERCA14-JEROUT14))/(VC*MINUTE*SECOND)
dCAI15/dT=-FI*C1*(ICANMDA15)-FI*(E*(JSERCA15-JEROUT15))/(VC*MINUTE*SECOND)
dCAI16/dT=-FI*C1*(ICANMDA16)-FI*(E*(JSERCA16-JEROUT16))/(VC*MINUTE*SECOND)
dCAI17/dT=-FI*C1*(ICANMDA17)-FI*(E*(JSERCA17-JEROUT17))/(VC*MINUTE*SECOND)
dCAI18/dT=-FI*C1*(ICANMDA18)-FI*(E*(JSERCA18-JEROUT18))/(VC*MINUTE*SECOND)
dCAI19/dT=-FI*C1*(ICANMDA19)-FI*(E*(JSERCA19-JEROUT19))/(VC*MINUTE*SECOND)
dCAI20/dT=-FI*C1*(ICANMDA20)-FI*(E*(JSERCA20-JEROUT20))/(VC*MINUTE*SECOND)
dCAI21/dT=-FI*C1*(ICANMDA21)-FI*(E*(JSERCA21-JEROUT21))/(VC*MINUTE*SECOND)
dCAI22/dT=-FI*C1*(ICANMDA22)-FI*(E*(JSERCA22-JEROUT22))/(VC*MINUTE*SECOND)
dCAI23/dT=-FI*C1*(ICANMDA23)-FI*(E*(JSERCA23-JEROUT23))/(VC*MINUTE*SECOND)
dCAI24/dT=-FI*C1*(ICANMDA24)-FI*(E*(JSERCA24-JEROUT24))/(VC*MINUTE*SECOND)
dCAI25/dT=-FI*C1*(ICANMDA25)-FI*(E*(JSERCA25-JEROUT25))/(VC*MINUTE*SECOND)
dHER1/dT=(DINH-(CAI1+DINH)*HER1)/TAU
dHER2/dT=(DINH-(CAI2+DINH)*HER2)/TAU
dHER3/dT=(DINH-(CAI3+DINH)*HER3)/TAU
dHER4/dT=(DINH-(CAI4+DINH)*HER4)/TAU
dHER5/dT=(DINH-(CAI5+DINH)*HER5)/TAU
dHER6/dT=(DINH-(CAI6+DINH)*HER6)/TAU
dHER7/dT=(DINH-(CAI7+DINH)*HER7)/TAU
dHER8/dT=(DINH-(CAI8+DINH)*HER8)/TAU
dHER9/dT=(DINH-(CAI9+DINH)*HER9)/TAU
dHER10/dT=(DINH-(CAI10+DINH)*HER10)/TAU
dHER11/dT=(DINH-(CAI11+DINH)*HER11)/TAU
dHER12/dT=(DINH-(CAI12+DINH)*HER12)/TAU
dHER13/dT=(DINH-(CAI13+DINH)*HER13)/TAU
dHER14/dT=(DINH-(CAI14+DINH)*HER14)/TAU
dHER15/dT=(DINH-(CAI15+DINH)*HER15)/TAU
dHER16/dT=(DINH-(CAI16+DINH)*HER16)/TAU
dHER17/dT=(DINH-(CAI17+DINH)*HER17)/TAU
dHER18/dT=(DINH-(CAI18+DINH)*HER18)/TAU
dHER19/dT=(DINH-(CAI19+DINH)*HER19)/TAU
dHER20/dT=(DINH-(CAI20+DINH)*HER20)/TAU
dHER21/dT=(DINH-(CAI21+DINH)*HER21)/TAU
dHER22/dT=(DINH-(CAI22+DINH)*HER22)/TAU
dHER23/dT=(DINH-(CAI23+DINH)*HER23)/TAU
dHER24/dT=(DINH-(CAI24+DINH)*HER24)/TAU
dHER25/dT=(DINH-(CAI25+DINH)*HER25)/TAU
dCAER1/dT=FI*(E*(JSERCA1-JEROUT1))/(VE*MINUTE*SECOND)
dCAER2/dT=FI*(E*(JSERCA2-JEROUT2))/(VE*MINUTE*SECOND)
dCAER3/dT=FI*(E*(JSERCA3-JEROUT3))/(VE*MINUTE*SECOND)
dCAER4/dT=FI*(E*(JSERCA4-JEROUT4))/(VE*MINUTE*SECOND)
dCAER5/dT=FI*(E*(JSERCA5-JEROUT5))/(VE*MINUTE*SECOND)
dCAER6/dT=FI*(E*(JSERCA6-JEROUT6))/(VE*MINUTE*SECOND)
dCAER7/dT=FI*(E*(JSERCA7-JEROUT7))/(VE*MINUTE*SECOND)
dCAER8/dT=FI*(E*(JSERCA8-JEROUT8))/(VE*MINUTE*SECOND)
dCAER9/dT=FI*(E*(JSERCA9-JEROUT9))/(VE*MINUTE*SECOND)
dCAER10/dT=FI*(E*(JSERCA10-JEROUT10))/(VE*MINUTE*SECOND)
dCAER11/dT=FI*(E*(JSERCA11-JEROUT11))/(VE*MINUTE*SECOND)
dCAER12/dT=FI*(E*(JSERCA12-JEROUT12))/(VE*MINUTE*SECOND)
dCAER13/dT=FI*(E*(JSERCA13-JEROUT13))/(VE*MINUTE*SECOND)
dCAER14/dT=FI*(E*(JSERCA14-JEROUT14))/(VE*MINUTE*SECOND)
dCAER15/dT=FI*(E*(JSERCA15-JEROUT15))/(VE*MINUTE*SECOND)
dCAER16/dT=FI*(E*(JSERCA16-JEROUT16))/(VE*MINUTE*SECOND)
dCAER17/dT=FI*(E*(JSERCA17-JEROUT17))/(VE*MINUTE*SECOND)
dCAER18/dT=FI*(E*(JSERCA18-JEROUT18))/(VE*MINUTE*SECOND)
dCAER19/dT=FI*(E*(JSERCA19-JEROUT19))/(VE*MINUTE*SECOND)
dCAER20/dT=FI*(E*(JSERCA20-JEROUT20))/(VE*MINUTE*SECOND)
dCAER21/dT=FI*(E*(JSERCA21-JEROUT21))/(VE*MINUTE*SECOND)
dCAER22/dT=FI*(E*(JSERCA22-JEROUT22))/(VE*MINUTE*SECOND)
dCAER23/dT=FI*(E*(JSERCA23-JEROUT23))/(VE*MINUTE*SECOND)
dCAER24/dT=FI*(E*(JSERCA24-JEROUT24))/(VE*MINUTE*SECOND)
dCAER25/dT=FI*(E*(JSERCA25-JEROUT25))/(VE*MINUTE*SECOND)
INAGL1=INAGL1
INAGL2=INAGL2
INAGL3=INAGL3
INAGL4=INAGL4
INAGL5=INAGL5
INAGL6=INAGL6
INAGL7=INAGL7
INAGL8=INAGL8
INAGL9=INAGL9
INAGL10=INAGL10
INAGL11=INAGL11
INAGL12=INAGL12
INAGL13=INAGL13
INAGL14=INAGL14
INAGL15=INAGL15
INAGL16=INAGL16
INAGL17=INAGL17
INAGL18=INAGL18
INAGL19=INAGL19
INAGL20=INAGL20
INAGL21=INAGL21
INAGL22=INAGL22
INAGL23=INAGL23
INAGL24=INAGL24
INAGL25=INAGL25

where ...
FRT = R*TEMP/F   
INANMDA1 = PNMDA*SG1*BINF(V1)*F*PHI(V1)*(NAE1*EXP(-PHI(V1))-NAI1)/(EXP(-PHI(V1))-1)   
INANMDA2 = PNMDA*SG2*BINF(V2)*F*PHI(V2)*(NAE2*EXP(-PHI(V2))-NAI2)/(EXP(-PHI(V2))-1)   
INANMDA3 = PNMDA*SG3*BINF(V3)*F*PHI(V3)*(NAE3*EXP(-PHI(V3))-NAI3)/(EXP(-PHI(V3))-1)   
INANMDA4 = PNMDA*SG4*BINF(V4)*F*PHI(V4)*(NAE4*EXP(-PHI(V4))-NAI4)/(EXP(-PHI(V4))-1)   
INANMDA5 = PNMDA*SG5*BINF(V5)*F*PHI(V5)*(NAE5*EXP(-PHI(V5))-NAI5)/(EXP(-PHI(V5))-1)   
INANMDA6 = PNMDA*SG6*BINF(V6)*F*PHI(V6)*(NAE6*EXP(-PHI(V6))-NAI6)/(EXP(-PHI(V6))-1)   
INANMDA7 = PNMDA*SG7*BINF(V7)*F*PHI(V7)*(NAE7*EXP(-PHI(V7))-NAI7)/(EXP(-PHI(V7))-1)   
INANMDA8 = PNMDA*SG8*BINF(V8)*F*PHI(V8)*(NAE8*EXP(-PHI(V8))-NAI8)/(EXP(-PHI(V8))-1)   
INANMDA9 = PNMDA*SG9*BINF(V9)*F*PHI(V9)*(NAE9*EXP(-PHI(V9))-NAI9)/(EXP(-PHI(V9))-1)   
INANMDA10 = PNMDA*SG10*BINF(V10)*F*PHI(V10)*(NAE10*EXP(-PHI(V10))-NAI10)/(EXP(-PHI(V10))-1)   
INANMDA11 = PNMDA*SG11*BINF(V11)*F*PHI(V11)*(NAE11*EXP(-PHI(V11))-NAI11)/(EXP(-PHI(V11))-1)   
INANMDA12 = PNMDA*SG12*BINF(V12)*F*PHI(V12)*(NAE12*EXP(-PHI(V12))-NAI12)/(EXP(-PHI(V12))-1)   
INANMDA13 = PNMDA*SG13*BINF(V13)*F*PHI(V13)*(NAE13*EXP(-PHI(V13))-NAI13)/(EXP(-PHI(V13))-1)   
INANMDA14 = PNMDA*SG14*BINF(V14)*F*PHI(V14)*(NAE14*EXP(-PHI(V14))-NAI14)/(EXP(-PHI(V14))-1)   
INANMDA15 = PNMDA*SG15*BINF(V15)*F*PHI(V15)*(NAE15*EXP(-PHI(V15))-NAI15)/(EXP(-PHI(V15))-1)   
INANMDA16 = PNMDA*SG16*BINF(V16)*F*PHI(V16)*(NAE16*EXP(-PHI(V16))-NAI16)/(EXP(-PHI(V16))-1)   
INANMDA17 = PNMDA*SG17*BINF(V17)*F*PHI(V17)*(NAE17*EXP(-PHI(V17))-NAI17)/(EXP(-PHI(V17))-1)   
INANMDA18 = PNMDA*SG18*BINF(V18)*F*PHI(V18)*(NAE18*EXP(-PHI(V18))-NAI18)/(EXP(-PHI(V18))-1)   
INANMDA19 = PNMDA*SG19*BINF(V19)*F*PHI(V19)*(NAE19*EXP(-PHI(V19))-NAI19)/(EXP(-PHI(V19))-1)   
INANMDA20 = PNMDA*SG20*BINF(V20)*F*PHI(V20)*(NAE20*EXP(-PHI(V20))-NAI20)/(EXP(-PHI(V20))-1)   
INANMDA21 = PNMDA*SG21*BINF(V21)*F*PHI(V21)*(NAE21*EXP(-PHI(V21))-NAI21)/(EXP(-PHI(V21))-1)   
INANMDA22 = PNMDA*SG22*BINF(V22)*F*PHI(V22)*(NAE22*EXP(-PHI(V22))-NAI22)/(EXP(-PHI(V22))-1)   
INANMDA23 = PNMDA*SG23*BINF(V23)*F*PHI(V23)*(NAE23*EXP(-PHI(V23))-NAI23)/(EXP(-PHI(V23))-1)   
INANMDA24 = PNMDA*SG24*BINF(V24)*F*PHI(V24)*(NAE24*EXP(-PHI(V24))-NAI24)/(EXP(-PHI(V24))-1)   
INANMDA25 = PNMDA*SG25*BINF(V25)*F*PHI(V25)*(NAE25*EXP(-PHI(V25))-NAI25)/(EXP(-PHI(V25))-1)   
IKNMDA1 = PNMDA*SG1*BINF(V1)*F*PHI(V1)*(KE1*EXP(-PHI(V1))-KI1)/(EXP(-PHI(V1))-1)   
IKNMDA2 = PNMDA*SG2*BINF(V2)*F*PHI(V2)*(KE2*EXP(-PHI(V2))-KI2)/(EXP(-PHI(V2))-1)   
IKNMDA3 = PNMDA*SG3*BINF(V3)*F*PHI(V3)*(KE3*EXP(-PHI(V3))-KI3)/(EXP(-PHI(V3))-1)   
IKNMDA4 = PNMDA*SG4*BINF(V4)*F*PHI(V4)*(KE4*EXP(-PHI(V4))-KI4)/(EXP(-PHI(V4))-1)   
IKNMDA5 = PNMDA*SG5*BINF(V5)*F*PHI(V5)*(KE5*EXP(-PHI(V5))-KI5)/(EXP(-PHI(V5))-1)   
IKNMDA6 = PNMDA*SG6*BINF(V6)*F*PHI(V6)*(KE6*EXP(-PHI(V6))-KI6)/(EXP(-PHI(V6))-1)   
IKNMDA7 = PNMDA*SG7*BINF(V7)*F*PHI(V7)*(KE7*EXP(-PHI(V7))-KI7)/(EXP(-PHI(V7))-1)   
IKNMDA8 = PNMDA*SG8*BINF(V8)*F*PHI(V8)*(KE8*EXP(-PHI(V8))-KI8)/(EXP(-PHI(V8))-1)   
IKNMDA9 = PNMDA*SG9*BINF(V9)*F*PHI(V9)*(KE9*EXP(-PHI(V9))-KI9)/(EXP(-PHI(V9))-1)   
IKNMDA10 = PNMDA*SG10*BINF(V10)*F*PHI(V10)*(KE10*EXP(-PHI(V10))-KI10)/(EXP(-PHI(V10))-1)   
IKNMDA11 = PNMDA*SG11*BINF(V11)*F*PHI(V11)*(KE11*EXP(-PHI(V11))-KI11)/(EXP(-PHI(V11))-1)   
IKNMDA12 = PNMDA*SG12*BINF(V12)*F*PHI(V12)*(KE12*EXP(-PHI(V12))-KI12)/(EXP(-PHI(V12))-1)   
IKNMDA13 = PNMDA*SG13*BINF(V13)*F*PHI(V13)*(KE13*EXP(-PHI(V13))-KI13)/(EXP(-PHI(V13))-1)   
IKNMDA14 = PNMDA*SG14*BINF(V14)*F*PHI(V14)*(KE14*EXP(-PHI(V14))-KI14)/(EXP(-PHI(V14))-1)   
IKNMDA15 = PNMDA*SG15*BINF(V15)*F*PHI(V15)*(KE15*EXP(-PHI(V15))-KI15)/(EXP(-PHI(V15))-1)   
IKNMDA16 = PNMDA*SG16*BINF(V16)*F*PHI(V16)*(KE16*EXP(-PHI(V16))-KI16)/(EXP(-PHI(V16))-1)   
IKNMDA17 = PNMDA*SG17*BINF(V17)*F*PHI(V17)*(KE17*EXP(-PHI(V17))-KI17)/(EXP(-PHI(V17))-1)   
IKNMDA18 = PNMDA*SG18*BINF(V18)*F*PHI(V18)*(KE18*EXP(-PHI(V18))-KI18)/(EXP(-PHI(V18))-1)   
IKNMDA19 = PNMDA*SG19*BINF(V19)*F*PHI(V19)*(KE19*EXP(-PHI(V19))-KI19)/(EXP(-PHI(V19))-1)   
IKNMDA20 = PNMDA*SG20*BINF(V20)*F*PHI(V20)*(KE20*EXP(-PHI(V20))-KI20)/(EXP(-PHI(V20))-1)   
IKNMDA21 = PNMDA*SG21*BINF(V21)*F*PHI(V21)*(KE21*EXP(-PHI(V21))-KI21)/(EXP(-PHI(V21))-1)   
IKNMDA22 = PNMDA*SG22*BINF(V22)*F*PHI(V22)*(KE22*EXP(-PHI(V22))-KI22)/(EXP(-PHI(V22))-1)   
IKNMDA23 = PNMDA*SG23*BINF(V23)*F*PHI(V23)*(KE23*EXP(-PHI(V23))-KI23)/(EXP(-PHI(V23))-1)   
IKNMDA24 = PNMDA*SG24*BINF(V24)*F*PHI(V24)*(KE24*EXP(-PHI(V24))-KI24)/(EXP(-PHI(V24))-1)   
IKNMDA25 = PNMDA*SG25*BINF(V25)*F*PHI(V25)*(KE25*EXP(-PHI(V25))-KI25)/(EXP(-PHI(V25))-1)   
ICANMDA1 = PCA*2*PNMDA*SG1*BINF(V1)*F*PHI(2*V1)*(CAE1*EXP(-PHI(2*V1))-CAI1)/(EXP(-PHI(2*V1))-1)   
ICANMDA2 = PCA*2*PNMDA*SG2*BINF(V2)*F*PHI(2*V2)*(CAE2*EXP(-PHI(2*V2))-CAI2)/(EXP(-PHI(2*V2))-1)   
ICANMDA3 = PCA*2*PNMDA*SG3*BINF(V3)*F*PHI(2*V3)*(CAE3*EXP(-PHI(2*V3))-CAI3)/(EXP(-PHI(2*V3))-1)   
ICANMDA4 = PCA*2*PNMDA*SG4*BINF(V4)*F*PHI(2*V4)*(CAE4*EXP(-PHI(2*V4))-CAI4)/(EXP(-PHI(2*V4))-1)   
ICANMDA5 = PCA*2*PNMDA*SG5*BINF(V5)*F*PHI(2*V5)*(CAE5*EXP(-PHI(2*V5))-CAI5)/(EXP(-PHI(2*V5))-1)   
ICANMDA6 = PCA*2*PNMDA*SG6*BINF(V6)*F*PHI(2*V6)*(CAE6*EXP(-PHI(2*V6))-CAI6)/(EXP(-PHI(2*V6))-1)   
ICANMDA7 = PCA*2*PNMDA*SG7*BINF(V7)*F*PHI(2*V7)*(CAE7*EXP(-PHI(2*V7))-CAI7)/(EXP(-PHI(2*V7))-1)   
ICANMDA8 = PCA*2*PNMDA*SG8*BINF(V8)*F*PHI(2*V8)*(CAE8*EXP(-PHI(2*V8))-CAI8)/(EXP(-PHI(2*V8))-1)   
ICANMDA9 = PCA*2*PNMDA*SG9*BINF(V9)*F*PHI(2*V9)*(CAE9*EXP(-PHI(2*V9))-CAI9)/(EXP(-PHI(2*V9))-1)   
ICANMDA10 = PCA*2*PNMDA*SG10*BINF(V10)*F*PHI(2*V10)*(CAE10*EXP(-PHI(2*V10))-CAI10)/(EXP(-PHI(2*V10))-1)   
ICANMDA11 = PCA*2*PNMDA*SG11*BINF(V11)*F*PHI(2*V11)*(CAE11*EXP(-PHI(2*V11))-CAI11)/(EXP(-PHI(2*V11))-1)   
ICANMDA12 = PCA*2*PNMDA*SG12*BINF(V12)*F*PHI(2*V12)*(CAE12*EXP(-PHI(2*V12))-CAI12)/(EXP(-PHI(2*V12))-1)   
ICANMDA13 = PCA*2*PNMDA*SG13*BINF(V13)*F*PHI(2*V13)*(CAE13*EXP(-PHI(2*V13))-CAI13)/(EXP(-PHI(2*V13))-1)   
ICANMDA14 = PCA*2*PNMDA*SG14*BINF(V14)*F*PHI(2*V14)*(CAE14*EXP(-PHI(2*V14))-CAI14)/(EXP(-PHI(2*V14))-1)   
ICANMDA15 = PCA*2*PNMDA*SG15*BINF(V15)*F*PHI(2*V15)*(CAE15*EXP(-PHI(2*V15))-CAI15)/(EXP(-PHI(2*V15))-1)   
ICANMDA16 = PCA*2*PNMDA*SG16*BINF(V16)*F*PHI(2*V16)*(CAE16*EXP(-PHI(2*V16))-CAI16)/(EXP(-PHI(2*V16))-1)   
ICANMDA17 = PCA*2*PNMDA*SG17*BINF(V17)*F*PHI(2*V17)*(CAE17*EXP(-PHI(2*V17))-CAI17)/(EXP(-PHI(2*V17))-1)   
ICANMDA18 = PCA*2*PNMDA*SG18*BINF(V18)*F*PHI(2*V18)*(CAE18*EXP(-PHI(2*V18))-CAI18)/(EXP(-PHI(2*V18))-1)   
ICANMDA19 = PCA*2*PNMDA*SG19*BINF(V19)*F*PHI(2*V19)*(CAE19*EXP(-PHI(2*V19))-CAI19)/(EXP(-PHI(2*V19))-1)   
ICANMDA20 = PCA*2*PNMDA*SG20*BINF(V20)*F*PHI(2*V20)*(CAE20*EXP(-PHI(2*V20))-CAI20)/(EXP(-PHI(2*V20))-1)   
ICANMDA21 = PCA*2*PNMDA*SG21*BINF(V21)*F*PHI(2*V21)*(CAE21*EXP(-PHI(2*V21))-CAI21)/(EXP(-PHI(2*V21))-1)   
ICANMDA22 = PCA*2*PNMDA*SG22*BINF(V22)*F*PHI(2*V22)*(CAE22*EXP(-PHI(2*V22))-CAI22)/(EXP(-PHI(2*V22))-1)   
ICANMDA23 = PCA*2*PNMDA*SG23*BINF(V23)*F*PHI(2*V23)*(CAE23*EXP(-PHI(2*V23))-CAI23)/(EXP(-PHI(2*V23))-1)   
ICANMDA24 = PCA*2*PNMDA*SG24*BINF(V24)*F*PHI(2*V24)*(CAE24*EXP(-PHI(2*V24))-CAI24)/(EXP(-PHI(2*V24))-1)   
ICANMDA25 = PCA*2*PNMDA*SG25*BINF(V25)*F*PHI(2*V25)*(CAE25*EXP(-PHI(2*V25))-CAI25)/(EXP(-PHI(2*V25))-1)   
INMDA1 = INANMDA1+IKNMDA1+ICANMDA1   
INMDA2 = INANMDA2+IKNMDA2+ICANMDA2   
INMDA3 = INANMDA3+IKNMDA3+ICANMDA3   
INMDA4 = INANMDA4+IKNMDA4+ICANMDA4   
INMDA5 = INANMDA5+IKNMDA5+ICANMDA5   
INMDA6 = INANMDA6+IKNMDA6+ICANMDA6   
INMDA7 = INANMDA7+IKNMDA7+ICANMDA7   
INMDA8 = INANMDA8+IKNMDA8+ICANMDA8   
INMDA9 = INANMDA9+IKNMDA9+ICANMDA9   
INMDA10 = INANMDA10+IKNMDA10+ICANMDA10   
INMDA11 = INANMDA11+IKNMDA11+ICANMDA11   
INMDA12 = INANMDA12+IKNMDA12+ICANMDA12   
INMDA13 = INANMDA13+IKNMDA13+ICANMDA13   
INMDA14 = INANMDA14+IKNMDA14+ICANMDA14   
INMDA15 = INANMDA15+IKNMDA15+ICANMDA15   
INMDA16 = INANMDA16+IKNMDA16+ICANMDA16   
INMDA17 = INANMDA17+IKNMDA17+ICANMDA17   
INMDA18 = INANMDA18+IKNMDA18+ICANMDA18   
INMDA19 = INANMDA19+IKNMDA19+ICANMDA19   
INMDA20 = INANMDA20+IKNMDA20+ICANMDA20   
INMDA21 = INANMDA21+IKNMDA21+ICANMDA21   
INMDA22 = INANMDA22+IKNMDA22+ICANMDA22   
INMDA23 = INANMDA23+IKNMDA23+ICANMDA23   
INMDA24 = INANMDA24+IKNMDA24+ICANMDA24   
INMDA25 = INANMDA25+IKNMDA25+ICANMDA25   
ICL1 = -PCL*F*PHI(-V1)*(CLE1*EXP(-PHI(-V1))-CLI1)/(EXP(-PHI(-V1))-1)   
ICL2 = -PCL*F*PHI(-V2)*(CLE2*EXP(-PHI(-V2))-CLI2)/(EXP(-PHI(-V2))-1)   
ICL3 = -PCL*F*PHI(-V3)*(CLE3*EXP(-PHI(-V3))-CLI3)/(EXP(-PHI(-V3))-1)   
ICL4 = -PCL*F*PHI(-V4)*(CLE4*EXP(-PHI(-V4))-CLI4)/(EXP(-PHI(-V4))-1)   
ICL5 = -PCL*F*PHI(-V5)*(CLE5*EXP(-PHI(-V5))-CLI5)/(EXP(-PHI(-V5))-1)   
ICL6 = -PCL*F*PHI(-V6)*(CLE6*EXP(-PHI(-V6))-CLI6)/(EXP(-PHI(-V6))-1)   
ICL7 = -PCL*F*PHI(-V7)*(CLE7*EXP(-PHI(-V7))-CLI7)/(EXP(-PHI(-V7))-1)   
ICL8 = -PCL*F*PHI(-V8)*(CLE8*EXP(-PHI(-V8))-CLI8)/(EXP(-PHI(-V8))-1)   
ICL9 = -PCL*F*PHI(-V9)*(CLE9*EXP(-PHI(-V9))-CLI9)/(EXP(-PHI(-V9))-1)   
ICL10 = -PCL*F*PHI(-V10)*(CLE10*EXP(-PHI(-V10))-CLI10)/(EXP(-PHI(-V10))-1)   
ICL11 = -PCL*F*PHI(-V11)*(CLE11*EXP(-PHI(-V11))-CLI11)/(EXP(-PHI(-V11))-1)   
ICL12 = -PCL*F*PHI(-V12)*(CLE12*EXP(-PHI(-V12))-CLI12)/(EXP(-PHI(-V12))-1)   
ICL13 = -PCL*F*PHI(-V13)*(CLE13*EXP(-PHI(-V13))-CLI13)/(EXP(-PHI(-V13))-1)   
ICL14 = -PCL*F*PHI(-V14)*(CLE14*EXP(-PHI(-V14))-CLI14)/(EXP(-PHI(-V14))-1)   
ICL15 = -PCL*F*PHI(-V15)*(CLE15*EXP(-PHI(-V15))-CLI15)/(EXP(-PHI(-V15))-1)   
ICL16 = -PCL*F*PHI(-V16)*(CLE16*EXP(-PHI(-V16))-CLI16)/(EXP(-PHI(-V16))-1)   
ICL17 = -PCL*F*PHI(-V17)*(CLE17*EXP(-PHI(-V17))-CLI17)/(EXP(-PHI(-V17))-1)   
ICL18 = -PCL*F*PHI(-V18)*(CLE18*EXP(-PHI(-V18))-CLI18)/(EXP(-PHI(-V18))-1)   
ICL19 = -PCL*F*PHI(-V19)*(CLE19*EXP(-PHI(-V19))-CLI19)/(EXP(-PHI(-V19))-1)   
ICL20 = -PCL*F*PHI(-V20)*(CLE20*EXP(-PHI(-V20))-CLI20)/(EXP(-PHI(-V20))-1)   
ICL21 = -PCL*F*PHI(-V21)*(CLE21*EXP(-PHI(-V21))-CLI21)/(EXP(-PHI(-V21))-1)   
ICL22 = -PCL*F*PHI(-V22)*(CLE22*EXP(-PHI(-V22))-CLI22)/(EXP(-PHI(-V22))-1)   
ICL23 = -PCL*F*PHI(-V23)*(CLE23*EXP(-PHI(-V23))-CLI23)/(EXP(-PHI(-V23))-1)   
ICL24 = -PCL*F*PHI(-V24)*(CLE24*EXP(-PHI(-V24))-CLI24)/(EXP(-PHI(-V24))-1)   
ICL25 = -PCL*F*PHI(-V25)*(CLE25*EXP(-PHI(-V25))-CLI25)/(EXP(-PHI(-V25))-1)   
IPUMP1 = IMAX/(((1+2/KE1)^2)*(1+7.7/NAI1)^3)   
IPUMP2 = IMAX/(((1+2/KE2)^2)*(1+7.7/NAI2)^3)   
IPUMP3 = IMAX/(((1+2/KE3)^2)*(1+7.7/NAI3)^3)   
IPUMP4 = IMAX/(((1+2/KE4)^2)*(1+7.7/NAI4)^3)   
IPUMP5 = IMAX/(((1+2/KE5)^2)*(1+7.7/NAI5)^3)   
IPUMP6 = IMAX/(((1+2/KE6)^2)*(1+7.7/NAI6)^3)   
IPUMP7 = IMAX/(((1+2/KE7)^2)*(1+7.7/NAI7)^3)   
IPUMP8 = IMAX/(((1+2/KE8)^2)*(1+7.7/NAI8)^3)   
IPUMP9 = IMAX/(((1+2/KE9)^2)*(1+7.7/NAI9)^3)   
IPUMP10 = IMAX/(((1+2/KE10)^2)*(1+7.7/NAI10)^3)   
IPUMP11 = IMAX/(((1+2/KE11)^2)*(1+7.7/NAI11)^3)   
IPUMP12 = IMAX/(((1+2/KE12)^2)*(1+7.7/NAI12)^3)   
IPUMP13 = IMAX/(((1+2/KE13)^2)*(1+7.7/NAI13)^3)   
IPUMP14 = IMAX/(((1+2/KE14)^2)*(1+7.7/NAI14)^3)   
IPUMP15 = IMAX/(((1+2/KE15)^2)*(1+7.7/NAI15)^3)   
IPUMP16 = IMAX/(((1+2/KE16)^2)*(1+7.7/NAI16)^3)   
IPUMP17 = IMAX/(((1+2/KE17)^2)*(1+7.7/NAI17)^3)   
IPUMP18 = IMAX/(((1+2/KE18)^2)*(1+7.7/NAI18)^3)   
IPUMP19 = IMAX/(((1+2/KE19)^2)*(1+7.7/NAI19)^3)   
IPUMP20 = IMAX/(((1+2/KE20)^2)*(1+7.7/NAI20)^3)   
IPUMP21 = IMAX/(((1+2/KE21)^2)*(1+7.7/NAI21)^3)   
IPUMP22 = IMAX/(((1+2/KE22)^2)*(1+7.7/NAI22)^3)   
IPUMP23 = IMAX/(((1+2/KE23)^2)*(1+7.7/NAI23)^3)   
IPUMP24 = IMAX/(((1+2/KE24)^2)*(1+7.7/NAI24)^3)   
IPUMP25 = IMAX/(((1+2/KE25)^2)*(1+7.7/NAI25)^3)   
INAPUMP1 = 3*IPUMP1   
INAPUMP2 = 3*IPUMP2   
INAPUMP3 = 3*IPUMP3   
INAPUMP4 = 3*IPUMP4   
INAPUMP5 = 3*IPUMP5   
INAPUMP6 = 3*IPUMP6   
INAPUMP7 = 3*IPUMP7   
INAPUMP8 = 3*IPUMP8   
INAPUMP9 = 3*IPUMP9   
INAPUMP10 = 3*IPUMP10   
INAPUMP11 = 3*IPUMP11   
INAPUMP12 = 3*IPUMP12   
INAPUMP13 = 3*IPUMP13   
INAPUMP14 = 3*IPUMP14   
INAPUMP15 = 3*IPUMP15   
INAPUMP16 = 3*IPUMP16   
INAPUMP17 = 3*IPUMP17   
INAPUMP18 = 3*IPUMP18   
INAPUMP19 = 3*IPUMP19   
INAPUMP20 = 3*IPUMP20   
INAPUMP21 = 3*IPUMP21   
INAPUMP22 = 3*IPUMP22   
INAPUMP23 = 3*IPUMP23   
INAPUMP24 = 3*IPUMP24   
INAPUMP25 = 3*IPUMP25   
IKPUMP1 = -2*IPUMP1   
IKPUMP2 = -2*IPUMP2   
IKPUMP3 = -2*IPUMP3   
IKPUMP4 = -2*IPUMP4   
IKPUMP5 = -2*IPUMP5   
IKPUMP6 = -2*IPUMP6   
IKPUMP7 = -2*IPUMP7   
IKPUMP8 = -2*IPUMP8   
IKPUMP9 = -2*IPUMP9   
IKPUMP10 = -2*IPUMP10   
IKPUMP11 = -2*IPUMP11   
IKPUMP12 = -2*IPUMP12   
IKPUMP13 = -2*IPUMP13   
IKPUMP14 = -2*IPUMP14   
IKPUMP15 = -2*IPUMP15   
IKPUMP16 = -2*IPUMP16   
IKPUMP17 = -2*IPUMP17   
IKPUMP18 = -2*IPUMP18   
IKPUMP19 = -2*IPUMP19   
IKPUMP20 = -2*IPUMP20   
IKPUMP21 = -2*IPUMP21   
IKPUMP22 = -2*IPUMP22   
IKPUMP23 = -2*IPUMP23   
IKPUMP24 = -2*IPUMP24   
IKPUMP25 = -2*IPUMP25   
KDIFF1 = DK*(KE2-KE1)   
KDIFF2 = DK*(KE3+KE1-2*KE2)   
KDIFF3 = DK*(KE4+KE2-2*KE3)   
KDIFF4 = DK*(KE5+KE3-2*KE4)   
KDIFF5 = DK*(KE6+KE4-2*KE5)   
KDIFF6 = DK*(KE7+KE5-2*KE6)   
KDIFF7 = DK*(KE8+KE6-2*KE7)   
KDIFF8 = DK*(KE9+KE7-2*KE8)   
KDIFF9 = DK*(KE10+KE8-2*KE9)   
KDIFF10 = DK*(KE11+KE9-2*KE10)   
KDIFF11 = DK*(KE12+KE10-2*KE11)   
KDIFF12 = DK*(KE13+KE11-2*KE12)   
KDIFF13 = DK*(KE14+KE12-2*KE13)   
KDIFF14 = DK*(KE15+KE13-2*KE14)   
KDIFF15 = DK*(KE16+KE14-2*KE15)   
KDIFF16 = DK*(KE17+KE15-2*KE16)   
KDIFF17 = DK*(KE18+KE16-2*KE17)   
KDIFF18 = DK*(KE19+KE17-2*KE18)   
KDIFF19 = DK*(KE20+KE18-2*KE19)   
KDIFF20 = DK*(KE21+KE19-2*KE20)   
KDIFF21 = DK*(KE22+KE20-2*KE21)   
KDIFF22 = DK*(KE23+KE21-2*KE22)   
KDIFF23 = DK*(KE24+KE22-2*KE23)   
KDIFF24 = DK*(KE25+KE23-2*KE24)   
KDIFF25 = DK*(KE24-KE25)   
NADIFF1 = DNA*(NAE2-NAE1)   
NADIFF2 = DNA*(NAE3+NAE1-2*NAE2)   
NADIFF3 = DNA*(NAE4+NAE2-2*NAE3)   
NADIFF4 = DNA*(NAE5+NAE3-2*NAE4)   
NADIFF5 = DNA*(NAE6+NAE4-2*NAE5)   
NADIFF6 = DNA*(NAE7+NAE5-2*NAE6)   
NADIFF7 = DNA*(NAE8+NAE6-2*NAE7)   
NADIFF8 = DNA*(NAE9+NAE7-2*NAE8)   
NADIFF9 = DNA*(NAE10+NAE8-2*NAE9)   
NADIFF10 = DNA*(NAE11+NAE9-2*NAE10)   
NADIFF11 = DNA*(NAE12+NAE10-2*NAE11)   
NADIFF12 = DNA*(NAE13+NAE11-2*NAE12)   
NADIFF13 = DNA*(NAE14+NAE12-2*NAE13)   
NADIFF14 = DNA*(NAE15+NAE13-2*NAE14)   
NADIFF15 = DNA*(NAE16+NAE14-2*NAE15)   
NADIFF16 = DNA*(NAE17+NAE15-2*NAE16)   
NADIFF17 = DNA*(NAE18+NAE16-2*NAE17)   
NADIFF18 = DNA*(NAE19+NAE17-2*NAE18)   
NADIFF19 = DNA*(NAE20+NAE18-2*NAE19)   
NADIFF20 = DNA*(NAE21+NAE19-2*NAE20)   
NADIFF21 = DNA*(NAE22+NAE20-2*NAE21)   
NADIFF22 = DNA*(NAE23+NAE21-2*NAE22)   
NADIFF23 = DNA*(NAE24+NAE22-2*NAE23)   
NADIFF24 = DNA*(NAE25+NAE23-2*NAE24)   
NADIFF25 = DNA*(NAE24-NAE25)   
GDIFF1 = DG*(GLUT2-GLUT1)   
GDIFF2 = DG*(GLUT3+GLUT1-2*GLUT2)   
GDIFF3 = DG*(GLUT4+GLUT2-2*GLUT3)   
GDIFF4 = DG*(GLUT5+GLUT3-2*GLUT4)   
GDIFF5 = DG*(GLUT6+GLUT4-2*GLUT5)   
GDIFF6 = DG*(GLUT7+GLUT5-2*GLUT6)   
GDIFF7 = DG*(GLUT8+GLUT6-2*GLUT7)   
GDIFF8 = DG*(GLUT9+GLUT7-2*GLUT8)   
GDIFF9 = DG*(GLUT10+GLUT8-2*GLUT9)   
GDIFF10 = DG*(GLUT11+GLUT9-2*GLUT10)   
GDIFF11 = DG*(GLUT12+GLUT10-2*GLUT11)   
GDIFF12 = DG*(GLUT13+GLUT11-2*GLUT12)   
GDIFF13 = DG*(GLUT14+GLUT12-2*GLUT13)   
GDIFF14 = DG*(GLUT15+GLUT13-2*GLUT14)   
GDIFF15 = DG*(GLUT16+GLUT14-2*GLUT15)   
GDIFF16 = DG*(GLUT17+GLUT15-2*GLUT16)   
GDIFF17 = DG*(GLUT18+GLUT16-2*GLUT17)   
GDIFF18 = DG*(GLUT19+GLUT17-2*GLUT18)   
GDIFF19 = DG*(GLUT20+GLUT18-2*GLUT19)   
GDIFF20 = DG*(GLUT21+GLUT19-2*GLUT20)   
GDIFF21 = DG*(GLUT22+GLUT20-2*GLUT21)   
GDIFF22 = DG*(GLUT23+GLUT21-2*GLUT22)   
GDIFF23 = DG*(GLUT24+GLUT22-2*GLUT23)   
GDIFF24 = DG*(GLUT25+GLUT23-2*GLUT24)   
GDIFF25 = DG*(GLUT24-GLUT25)   
ENAGL1 = (FRT/2)*LN(((NAE1/NAIA1)^3)*(KIA1/KE1)*(GLUT1/GLUI1)*HR)   
ENAGL2 = (FRT/2)*LN(((NAE2/NAIA2)^3)*(KIA2/KE2)*(GLUT2/GLUI2)*HR)   
ENAGL3 = (FRT/2)*LN(((NAE3/NAIA3)^3)*(KIA3/KE3)*(GLUT3/GLUI3)*HR)   
ENAGL4 = (FRT/2)*LN(((NAE4/NAIA4)^3)*(KIA4/KE4)*(GLUT4/GLUI4)*HR)   
ENAGL5 = (FRT/2)*LN(((NAE5/NAIA5)^3)*(KIA5/KE5)*(GLUT5/GLUI5)*HR)   
ENAGL6 = (FRT/2)*LN(((NAE6/NAIA6)^3)*(KIA6/KE6)*(GLUT6/GLUI6)*HR)   
ENAGL7 = (FRT/2)*LN(((NAE7/NAIA7)^3)*(KIA7/KE7)*(GLUT7/GLUI7)*HR)   
ENAGL8 = (FRT/2)*LN(((NAE8/NAIA8)^3)*(KIA8/KE8)*(GLUT8/GLUI8)*HR)   
ENAGL9 = (FRT/2)*LN(((NAE9/NAIA9)^3)*(KIA9/KE9)*(GLUT9/GLUI9)*HR)   
ENAGL10 = (FRT/2)*LN(((NAE10/NAIA10)^3)*(KIA10/KE10)*(GLUT10/GLUI10)*HR)   
ENAGL11 = (FRT/2)*LN(((NAE11/NAIA11)^3)*(KIA11/KE11)*(GLUT11/GLUI11)*HR)   
ENAGL12 = (FRT/2)*LN(((NAE12/NAIA12)^3)*(KIA12/KE12)*(GLUT12/GLUI12)*HR)   
ENAGL13 = (FRT/2)*LN(((NAE13/NAIA13)^3)*(KIA13/KE13)*(GLUT13/GLUI13)*HR)   
ENAGL14 = (FRT/2)*LN(((NAE14/NAIA14)^3)*(KIA14/KE14)*(GLUT14/GLUI14)*HR)   
ENAGL15 = (FRT/2)*LN(((NAE15/NAIA15)^3)*(KIA15/KE15)*(GLUT15/GLUI15)*HR)   
ENAGL16 = (FRT/2)*LN(((NAE16/NAIA16)^3)*(KIA16/KE16)*(GLUT16/GLUI16)*HR)   
ENAGL17 = (FRT/2)*LN(((NAE17/NAIA17)^3)*(KIA17/KE17)*(GLUT17/GLUI17)*HR)   
ENAGL18 = (FRT/2)*LN(((NAE18/NAIA18)^3)*(KIA18/KE18)*(GLUT18/GLUI18)*HR)   
ENAGL19 = (FRT/2)*LN(((NAE19/NAIA19)^3)*(KIA19/KE19)*(GLUT19/GLUI19)*HR)   
ENAGL20 = (FRT/2)*LN(((NAE20/NAIA20)^3)*(KIA20/KE20)*(GLUT20/GLUI20)*HR)   
ENAGL21 = (FRT/2)*LN(((NAE21/NAIA21)^3)*(KIA21/KE21)*(GLUT21/GLUI21)*HR)   
ENAGL22 = (FRT/2)*LN(((NAE22/NAIA22)^3)*(KIA22/KE22)*(GLUT22/GLUI22)*HR)   
ENAGL23 = (FRT/2)*LN(((NAE23/NAIA23)^3)*(KIA23/KE23)*(GLUT23/GLUI23)*HR)   
ENAGL24 = (FRT/2)*LN(((NAE24/NAIA24)^3)*(KIA24/KE24)*(GLUT24/GLUI24)*HR)   
ENAGL25 = (FRT/2)*LN(((NAE25/NAIA25)^3)*(KIA25/KE25)*(GLUT25/GLUI25)*HR)   
INAGL1 = GNAGL*(VA1-ENAGL1)   
INAGL2 = GNAGL*(VA2-ENAGL2)   
INAGL3 = GNAGL*(VA3-ENAGL3)   
INAGL4 = GNAGL*(VA4-ENAGL4)   
INAGL5 = GNAGL*(VA5-ENAGL5)   
INAGL6 = GNAGL*(VA6-ENAGL6)   
INAGL7 = GNAGL*(VA7-ENAGL7)   
INAGL8 = GNAGL*(VA8-ENAGL8)   
INAGL9 = GNAGL*(VA9-ENAGL9)   
INAGL10 = GNAGL*(VA10-ENAGL10)   
INAGL11 = GNAGL*(VA11-ENAGL11)   
INAGL12 = GNAGL*(VA12-ENAGL12)   
INAGL13 = GNAGL*(VA13-ENAGL13)   
INAGL14 = GNAGL*(VA14-ENAGL14)   
INAGL15 = GNAGL*(VA15-ENAGL15)   
INAGL16 = GNAGL*(VA16-ENAGL16)   
INAGL17 = GNAGL*(VA17-ENAGL17)   
INAGL18 = GNAGL*(VA18-ENAGL18)   
INAGL19 = GNAGL*(VA19-ENAGL19)   
INAGL20 = GNAGL*(VA20-ENAGL20)   
INAGL21 = GNAGL*(VA21-ENAGL21)   
INAGL22 = GNAGL*(VA22-ENAGL22)   
INAGL23 = GNAGL*(VA23-ENAGL23)   
INAGL24 = GNAGL*(VA24-ENAGL24)   
INAGL25 = GNAGL*(VA25-ENAGL25)   
VOLE = DELTA*VOLN   
C1 = 10.0*S/(F*VOLN)   
C2 = 10.0*S/(F*VOLE)   
C3A = 10*SA/(F*VOLA)   
C3E = 10*SA/(F*VOLE)   
GLUI1 = (1/C3E)*(GLTOT-C3A*GLUT1)   
GLUI2 = (1/C3E)*(GLTOT-C3A*GLUT2)   
GLUI3 = (1/C3E)*(GLTOT-C3A*GLUT3)   
GLUI4 = (1/C3E)*(GLTOT-C3A*GLUT4)   
GLUI5 = (1/C3E)*(GLTOT-C3A*GLUT5)   
GLUI6 = (1/C3E)*(GLTOT-C3A*GLUT6)   
GLUI7 = (1/C3E)*(GLTOT-C3A*GLUT7)   
GLUI8 = (1/C3E)*(GLTOT-C3A*GLUT8)   
GLUI9 = (1/C3E)*(GLTOT-C3A*GLUT9)   
GLUI10 = (1/C3E)*(GLTOT-C3A*GLUT10)   
GLUI11 = (1/C3E)*(GLTOT-C3A*GLUT11)   
GLUI12 = (1/C3E)*(GLTOT-C3A*GLUT12)   
GLUI13 = (1/C3E)*(GLTOT-C3A*GLUT13)   
GLUI14 = (1/C3E)*(GLTOT-C3A*GLUT14)   
GLUI15 = (1/C3E)*(GLTOT-C3A*GLUT15)   
GLUI16 = (1/C3E)*(GLTOT-C3A*GLUT16)   
GLUI17 = (1/C3E)*(GLTOT-C3A*GLUT17)   
GLUI18 = (1/C3E)*(GLTOT-C3A*GLUT18)   
GLUI19 = (1/C3E)*(GLTOT-C3A*GLUT19)   
GLUI20 = (1/C3E)*(GLTOT-C3A*GLUT20)   
GLUI21 = (1/C3E)*(GLTOT-C3A*GLUT21)   
GLUI22 = (1/C3E)*(GLTOT-C3A*GLUT22)   
GLUI23 = (1/C3E)*(GLTOT-C3A*GLUT23)   
GLUI24 = (1/C3E)*(GLTOT-C3A*GLUT24)   
GLUI25 = (1/C3E)*(GLTOT-C3A*GLUT25)   
GLTOT = C3E*GLUI0+C3A*GLUT0   
JEROUT1 = (VIP3*((IP3/(IP3+DIP3))^3)*((CAI1/(CAI1+DACT))^3)*(HER1^3)+VLEAK)*(CAER1-CAI1)   
JEROUT2 = (VIP3*((IP3/(IP3+DIP3))^3)*((CAI2/(CAI2+DACT))^3)*(HER2^3)+VLEAK)*(CAER2-CAI2)   
JEROUT3 = (VIP3*((IP3/(IP3+DIP3))^3)*((CAI3/(CAI3+DACT))^3)*(HER3^3)+VLEAK)*(CAER3-CAI3)   
JEROUT4 = (VIP3*((IP3/(IP3+DIP3))^3)*((CAI4/(CAI4+DACT))^3)*(HER4^3)+VLEAK)*(CAER4-CAI4)   
JEROUT5 = (VIP3*((IP3/(IP3+DIP3))^3)*((CAI5/(CAI5+DACT))^3)*(HER5^3)+VLEAK)*(CAER5-CAI5)   
JEROUT6 = (VIP3*((IP3/(IP3+DIP3))^3)*((CAI6/(CAI6+DACT))^3)*(HER6^3)+VLEAK)*(CAER6-CAI6)   
JEROUT7 = (VIP3*((IP3/(IP3+DIP3))^3)*((CAI7/(CAI7+DACT))^3)*(HER7^3)+VLEAK)*(CAER7-CAI7)   
JEROUT8 = (VIP3*((IP3/(IP3+DIP3))^3)*((CAI8/(CAI8+DACT))^3)*(HER8^3)+VLEAK)*(CAER8-CAI8)   
JEROUT9 = (VIP3*((IP3/(IP3+DIP3))^3)*((CAI9/(CAI9+DACT))^3)*(HER9^3)+VLEAK)*(CAER9-CAI9)   
JEROUT10 = (VIP3*((IP3/(IP3+DIP3))^3)*((CAI10/(CAI10+DACT))^3)*(HER10^3)+VLEAK)*(CAER10-CAI10)   
JEROUT11 = (VIP3*((IP3/(IP3+DIP3))^3)*((CAI11/(CAI11+DACT))^3)*(HER11^3)+VLEAK)*(CAER11-CAI11)   
JEROUT12 = (VIP3*((IP3/(IP3+DIP3))^3)*((CAI12/(CAI12+DACT))^3)*(HER12^3)+VLEAK)*(CAER12-CAI12)   
JEROUT13 = (VIP3*((IP3/(IP3+DIP3))^3)*((CAI13/(CAI13+DACT))^3)*(HER13^3)+VLEAK)*(CAER13-CAI13)   
JEROUT14 = (VIP3*((IP3/(IP3+DIP3))^3)*((CAI14/(CAI14+DACT))^3)*(HER14^3)+VLEAK)*(CAER14-CAI14)   
JEROUT15 = (VIP3*((IP3/(IP3+DIP3))^3)*((CAI15/(CAI15+DACT))^3)*(HER15^3)+VLEAK)*(CAER15-CAI15)   
JEROUT16 = (VIP3*((IP3/(IP3+DIP3))^3)*((CAI16/(CAI16+DACT))^3)*(HER16^3)+VLEAK)*(CAER16-CAI16)   
JEROUT17 = (VIP3*((IP3/(IP3+DIP3))^3)*((CAI17/(CAI17+DACT))^3)*(HER17^3)+VLEAK)*(CAER17-CAI17)   
JEROUT18 = (VIP3*((IP3/(IP3+DIP3))^3)*((CAI18/(CAI18+DACT))^3)*(HER18^3)+VLEAK)*(CAER18-CAI18)   
JEROUT19 = (VIP3*((IP3/(IP3+DIP3))^3)*((CAI19/(CAI19+DACT))^3)*(HER19^3)+VLEAK)*(CAER19-CAI19)   
JEROUT20 = (VIP3*((IP3/(IP3+DIP3))^3)*((CAI20/(CAI20+DACT))^3)*(HER20^3)+VLEAK)*(CAER20-CAI20)   
JEROUT21 = (VIP3*((IP3/(IP3+DIP3))^3)*((CAI21/(CAI21+DACT))^3)*(HER21^3)+VLEAK)*(CAER21-CAI21)   
JEROUT22 = (VIP3*((IP3/(IP3+DIP3))^3)*((CAI22/(CAI22+DACT))^3)*(HER22^3)+VLEAK)*(CAER22-CAI22)   
JEROUT23 = (VIP3*((IP3/(IP3+DIP3))^3)*((CAI23/(CAI23+DACT))^3)*(HER23^3)+VLEAK)*(CAER23-CAI23)   
JEROUT24 = (VIP3*((IP3/(IP3+DIP3))^3)*((CAI24/(CAI24+DACT))^3)*(HER24^3)+VLEAK)*(CAER24-CAI24)   
JEROUT25 = (VIP3*((IP3/(IP3+DIP3))^3)*((CAI25/(CAI25+DACT))^3)*(HER25^3)+VLEAK)*(CAER25-CAI25)   
JSERCA1 = VSERCA*CAI1^2/(KSERCA^2+CAI1^2)   
JSERCA2 = VSERCA*CAI2^2/(KSERCA^2+CAI2^2)   
JSERCA3 = VSERCA*CAI3^2/(KSERCA^2+CAI3^2)   
JSERCA4 = VSERCA*CAI4^2/(KSERCA^2+CAI4^2)   
JSERCA5 = VSERCA*CAI5^2/(KSERCA^2+CAI5^2)   
JSERCA6 = VSERCA*CAI6^2/(KSERCA^2+CAI6^2)   
JSERCA7 = VSERCA*CAI7^2/(KSERCA^2+CAI7^2)   
JSERCA8 = VSERCA*CAI8^2/(KSERCA^2+CAI8^2)   
JSERCA9 = VSERCA*CAI9^2/(KSERCA^2+CAI9^2)   
JSERCA10 = VSERCA*CAI10^2/(KSERCA^2+CAI10^2)   
JSERCA11 = VSERCA*CAI11^2/(KSERCA^2+CAI11^2)   
JSERCA12 = VSERCA*CAI12^2/(KSERCA^2+CAI12^2)   
JSERCA13 = VSERCA*CAI13^2/(KSERCA^2+CAI13^2)   
JSERCA14 = VSERCA*CAI14^2/(KSERCA^2+CAI14^2)   
JSERCA15 = VSERCA*CAI15^2/(KSERCA^2+CAI15^2)   
JSERCA16 = VSERCA*CAI16^2/(KSERCA^2+CAI16^2)   
JSERCA17 = VSERCA*CAI17^2/(KSERCA^2+CAI17^2)   
JSERCA18 = VSERCA*CAI18^2/(KSERCA^2+CAI18^2)   
JSERCA19 = VSERCA*CAI19^2/(KSERCA^2+CAI19^2)   
JSERCA20 = VSERCA*CAI20^2/(KSERCA^2+CAI20^2)   
JSERCA21 = VSERCA*CAI21^2/(KSERCA^2+CAI21^2)   
JSERCA22 = VSERCA*CAI22^2/(KSERCA^2+CAI22^2)   
JSERCA23 = VSERCA*CAI23^2/(KSERCA^2+CAI23^2)   
JSERCA24 = VSERCA*CAI24^2/(KSERCA^2+CAI24^2)   
JSERCA25 = VSERCA*CAI25^2/(KSERCA^2+CAI25^2)   
E = VG*PER*DER   
VC = VG*PCYTOSOL   
VE = VG*PER   

User-defined functions:
PHI(V) = V/FRT  
MINF(V) = 1./(1.+EXP(-(V-THM)/SIGM))  
INA(V,N,NAE,NAI) = PNA*(MINF(V)^3*(1-N)+PNAL)*F*PHI(V)*(NAE*EXP(-PHI(V))-NAI)/(EXP(-PHI(V))-1)  
MINFP(V) = 1./(1.+EXP(-(V-THMP)/SIGMP))  
HINFP(V) = 1./(1.+EXP(-(V-THHP)/SIGHP))  
TAUHP(V) = TAUBAR/COSH((V-VT)/(2*SIG))  
INAP(V,HP,NAE,NAI) = PNAP*MINFP(V)*HP*F*PHI(V)*(NAE*EXP(-PHI(V))-NAI)/(EXP(-PHI(V))-1)  
NINF(V) = 1./(1.+EXP(-(V-THN)/SGN))  
TAUN(V) = TAUN0+TAUN1/(1+EXP(-(V-THNT)/SN))  
IK(V,N,KE,KI) = PK*(N^4+PKL)*F*PHI(V)*(KE*EXP(-PHI(V))-KI)/(EXP(-PHI(V))-1)  
BINF(V) = 1/(1+EXP(-(V-THETAT)/16.13))  
SINFG(X) = 1./(1.+EXP(-(X-THG)/SIGMAG))  
INAA(V,NAE,NAI) = PNAA*F*PHI(V)*(NAE*EXP(-PHI(V))-NAI)/(EXP(-PHI(V))-1)  
IKA(V,KE,KI) = PKA*F*PHI(V)*(KE*EXP(-PHI(V))-KI)/(EXP(-PHI(V))-1)  
IPUMPA(KE,NAI,IMAXA) = IMAXA/(((1+2/KE)^2)*(1+10/NAI)^3)