QIF method to estimate synaptic conductances (Vich et al 2017)

 Download zip file 
Help downloading and running models
"Subthreshold fluctuations in neuronal membrane potential traces contain nonlinear components, and employing nonlinear models might improve the statistical inference. We propose a new strategy to estimate synaptic conductances, which has been tested using in silico data and applied to in vivo recordings. The model is constructed to capture the nonlinearities caused by subthreshold activated currents, and the estimation procedure can discern between excitatory and inhibitory conductances using only one membrane potential trace. ... The results show an improvement compared to existent procedures for the models tested here."
1 . Vich C, Berg RW, Guillamon A, Ditlevsen S (2017) Estimation of Synaptic Conductances in Presence of Nonlinear Effects Caused by Subthreshold Ionic Currents. Front Comput Neurosci 11:69 [PubMed]
Citations  Citation Browser
Model Information (Click on a link to find other models with that property)
Model Type: Synapse;
Brain Region(s)/Organism:
Cell Type(s): Abstract quadratic integrate-and-fire;
Gap Junctions:
Simulation Environment: MATLAB;
Model Concept(s): Conductances estimation;
Implementer(s): Vich, Catalina [catalina.vich at uib.es];