"Many animals rely on an internal heading representation when
navigating in varied environments. How this
representation is linked to the sensory cues that define different
surroundings is unclear. In the fly brain, heading is represented by
‘compass’ neurons that innervate a ring-shaped structure known as the
ellipsoid body. Each compass neuron receives inputs from ‘ring’
neurons that are selective for particular visual features;
this combination provides an ideal substrate for the extraction of
directional information from a visual scene. Here we combine
two-photon calcium imaging and optogenetics in tethered flying flies
with circuit modelling, and show how the correlated activity of
compass and visual neurons drives plasticity, which
flexibly transforms two-dimensional visual cues into a stable heading
representation. ... "
See the supplementary information for model details.
Kim SS, Hermundstad AM, Romani S, Abbott LF, Jayaraman V (2019) Generation of stable heading representations in diverse visual scenes. Nature 576:126-131 [PubMed]