Advanced search
User account
Login
Register
Find models by
Model name
First author
Each author
Find models for
Brain region
Concept
Find models of
Realistic Microcircuits
Connectionist Networks
L5 cortical neurons with recreated synaptic inputs in vitro correlation transfer (Linaro et al 2019)
 
Download zip file
Help downloading and running models
Model Information
Model File
Accession:
261899
"...We studied pyramidal neurons and two classes of GABAergic interneurons of layer 5 in neocortical brain slices obtained from rats of both sexes, and we stimulated them with biophysically realistic correlated inputs, generated using dynamic clamp. We found that the physiological differences between cell types manifested unique features in their capacity to transfer correlated inputs. We used linear response theory and computational modeling to gain clear insights into how cellular properties determine both the gain and timescale of correlation transfer, thus tying single-cell features with network interactions. Our results provide further ground for the functionally distinct roles played by various types of neuronal cells in the cortical microcircuit..."
Reference:
1 .
Linaro D, Ocker GK, Doiron B, Giugliano M (2019) Correlation Transfer by Layer 5 Cortical Neurons Under Recreated Synaptic Inputs In Vitro.
J Neurosci
39
:7648-7663
[
PubMed
]
Citations
Citation Browser
Model Information
(Click on a link to find other models with that property)
Model Type:
Neuron or other electrically excitable cell;
Brain Region(s)/Organism:
Neocortex;
Cell Type(s):
Abstract integrate-and-fire adaptive exponential (AdEx) neuron;
Channel(s):
Gap Junctions:
Receptor(s):
Gene(s):
Transmitter(s):
Gaba;
Simulation Environment:
MATLAB;
Model Concept(s):
Implementer(s):
Ocker, Gabriel K ;
Search NeuronDB
for information about:
Gaba
;
/
gko_celltypes_correlation
File not selected
<- Select file from this column.