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Healthy and Epileptic Hippocampal Circuit (Aussel et al 2022)
 
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Model Information
Model File
Accession:
266796
This model aims at reproducing healthy and epileptic hippocampal oscillations, and includes modeling of the sleep-wake cycle. It was used to study theta-nested gamma oscillations, sharp-wave ripple complexes,
Reference:
1 .
Aussel A, Ranta R, Aron O, Colnat-Coulbois S, Maillard L, Buhry L (2022) Cell to network computational model of the epileptic human hippocampus suggests specific roles of network and channel dysfunctions in the ictal and interictal oscillations
J Computational Neuroscience
[
PubMed
]
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Model Information
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Model Type:
Realistic Network;
Brain Region(s)/Organism:
Hippocampus;
Cell Type(s):
Hodgkin-Huxley neuron;
Channel(s):
Gap Junctions:
Receptor(s):
Gene(s):
Transmitter(s):
Simulation Environment:
Brian 2;
Model Concept(s):
Epilepsy;
Sleep-Wake transition;
Implementer(s):
Aussel, Amélie [amelie.aussel at loria.fr];
/
model_hipp_final
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