Short term plasticity of synapses onto V1 layer 2/3 pyramidal neuron (Varela et al 1997)

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Accession:3264
This archive contains 3 mod files for NEURON that implement the short term synaptic plasticity model described in Varela, J.A., Sen, K., Gibson, J., Fost, J., Abbott, L.R., and Nelson, S.B.. A quantitative description of short-term plasticity at excitatory synapses in layer 2/3 of rat primary visual cortex. Journal of Neuroscience 17:7926-7940, 1997. Contact ted.carnevale@yale.edu if you have questions about this implementation of the model.
Reference:
1 . Varela JA, Sen K, Gibson J, Fost J, Abbott LF, Nelson SB (1997) A quantitative description of short-term plasticity at excitatory synapses in layer 2/3 of rat primary visual cortex. J Neurosci 17:7926-40 [PubMed]
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Model Information (Click on a link to find other models with that property)
Model Type: Synapse;
Brain Region(s)/Organism: Visual cortex;
Cell Type(s): Neocortex L2/3 pyramidal GLU cell;
Channel(s): I Na,t; I K;
Gap Junctions:
Receptor(s): AMPA;
Gene(s):
Transmitter(s): Glutamate;
Simulation Environment: NEURON;
Model Concept(s): Synaptic Plasticity; Short-term Synaptic Plasticity; Facilitation; Depression; Vision;
Implementer(s): Carnevale, Ted [Ted.Carnevale at Yale.edu];
Search NeuronDB for information about:  Neocortex L2/3 pyramidal GLU cell; AMPA; I Na,t; I K; Glutamate;
objectvar save_window_, rvp_
objectvar scene_vector_[4]
objectvar ocbox_, ocbox_list_, scene_, scene_list_
{ocbox_list_ = new List()  scene_list_ = new List()}

//Begin ArtCellGUI[0]
{
load_file("netbild.hoc")
}
ocbox_ = new ArtCellGUI(1)
{object_push(ocbox_)}
{
tobj = new MechanismStandard("NetStim")
tobj.set("interval", 50, 0)
tobj.set("number", 10, 0)
tobj.set("start", 50, 0)
tobj.set("noise", 1, 0)
}
{append(tobj, "S")}
{
tobj = new MechanismStandard("FDSIntFire")
tobj.set("tau", 10, 0)
tobj.set("spikedur", 1, 0)
tobj.set("refrac", 5, 0)
tobj.set("f", 0.917, 0)
tobj.set("tau_F", 94, 0)
tobj.set("d1", 0.416, 0)
tobj.set("tau_D1", 380, 0)
tobj.set("d2", 0.975, 0)
tobj.set("tau_D2", 9200, 0)
}
{append(tobj, "C")}
{object_pop()}
{
ocbox_.map("ArtCellGUI[0]", 6, 83, 449.28, 311.04)
}
objref ocbox_
//End ArtCellGUI[0]

{WindowMenu[0].ses_gid(1, 0, 1, "allwindows")}
objectvar scene_vector_[1]
{doNotify()}