I A in Kenyon cells resemble Shaker currents (Pelz et al 1999)

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Accession:34560
Cultured Kenyon cells from the mushroom body of the honeybee, Apis mellifera, show a voltage-gated, fast transient K1 current that is sensitive to 4-aminopyridine, an A current. The kinetic properties of this A current and its modulation by extracellular K1 ions were investigated in vitro with the whole cell patch-clamp technique. The A current was isolated from other voltage-gated currents either pharmacologically or with suitable voltage-clamp protocols. Hodgkin- and Huxley-style mathematical equations were used for the description of this current and for the simulation of action potentials in a Kenyon cell model. The data of the A current were incorporated into a reduced computational model of the voltage-gated currents of Kenyon cells. In addition, the model contained a delayed rectifier K current, a Na current, and a leakage current. The model reproduces several experimental features and makes predictions. See paper for details and results.
Reference:
1 . Pelz C, Jander J, Rosenboom H, Hammer M, Menzel R (1999) IA in Kenyon cells of the mushroom body of honeybees resembles shaker currents: kinetics, modulation by K+, and simulation. J Neurophysiol 81:1749-59 [PubMed]
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Model Information (Click on a link to find other models with that property)
Model Type: Neuron or other electrically excitable cell;
Brain Region(s)/Organism:
Cell Type(s): Honeybee kenyon cell;
Channel(s): I Na,t; I A; I K;
Gap Junctions:
Receptor(s):
Gene(s):
Transmitter(s):
Simulation Environment: SNNAP;
Model Concept(s): Ion Channel Kinetics; Parameter Fitting; Action Potentials; Invertebrate;
Implementer(s): Baxter, Douglas;
Search NeuronDB for information about:  I Na,t; I A; I K;
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>----------------------->------------------------------->
  LIST_NEURONS:		>   List of H-H Neurons		>
>.......................>...............................>
	A               >	Neuron's name		>
	Kenyon.neu      >	File Name		>
	green           >	Color Name		>
>.......................>...............................>
>	B               >	Neuron's name		>
>	filename.neu    >	File Name		>
>	green           >	Color Name		>
>.......................>...............................>
	END		>				>
>----------------------->------------------------------->

>----------------------->------------------------------->
>  CHEMSYN:		>	Chemical synapse	>
>.......................>...............................>
>	B               > Name of postsynaptic neuron	>
>	A               > Name of presynaptic neuron	>
>	exc             > type of synapse		>
>	filename.cs     > File Name			>
>	green           > Color Name			>
>.......................>...............................>
>	END		>				>
>----------------------->------------------------------->

>----------------------->------------------------------->
>  ELCTRCPL:		>	Electrical coupling	>
>.......................>...............................>
>	B               > Name of postsynaptic neuron	>
>	A               > Name of presynaptic neuron	>
>	filename.es     > File Name			>
>	green           > Color Name			>
>.......................>...............................>
>	END		>				>
>----------------------->------------------------------->

>----------------------->------------------------------->
>  MODULSYN:		>	Modulatory synapse	>
>.......................>...............................>
>	A               > Name of postsynaptic neuron	>
>	B               > Name of presynaptic neuron	>
>	SM              > Name of Second Messenger	>
>	mod             > type of synapse		>
>	filename.ms     > File Name			>
>	green           > Color Name			>
>.......................>...............................>
>	END		>				>
>----------------------->------------------------------->

END